phaA

Acetyl-CoA acetyltransferase

396 amino acids

When expressed in E.coli with Synechocystis PhaB, PhaC and PhaE confers the ability to synthesize up to 12% (w/w) poly(3-hydroxybutyrate) (PHB) depending on the carbon source.

Belongs to the thiolase-like superfamily. Thiolase family.

41.71 kDa

MRDVFIVAAKRTPLGRFGGSLTNFSAADLGAHVMKSVLAQAGVGGDQLDLYIMGNVLRAGHGQLIPRQAALKAEIPDTVDGYAVDMVCSSAMMSVINAALTIRAGEGDLILAGGTESMSQTGFYLSHRARWGYKFLMGAPENLTDLLLHDGLTDSTNGEGMGEQTEKLAAEHGFSRIELDEVACLSQQRAAHATESGYFDSEIAPIEITSRKGTQVLASDEGIRSDTTVESLGKLRSAFAKDGVLTAGNCSQITDGAAALLLASGEAVEKYQLKPLAKILGGSWAAGTPSRFPELPITASQKLLAKLDKTLADFDLFENNEAFSVSNLLFERRLGVDRDKLNVNGGAIALGHPIGASGARIMVTLLYALQQRDKTLGLAALCHGTGGGTAIALERV

phaA

Acetyl-CoA acetyltransferase

394 amino acids

Belongs to the thiolase-like superfamily. Thiolase family.

40.897 kDa

MSDTIVIVDAGRTAIGTFGGALSALQATDIGTTVLKALIERTGIAPEQVSEVILGQVLTAGCGQNPARQTTLMAGLPHTVPAMTINKVCGSGLKAVHLAMQAVACGDAEIVIAGGQESMSQSSHVLPRSREGQRMGDWPMKDTMIVDGLWDAFNQCHMGVTAENIAKKYAFTREAQDAFAAASQQKAEAAIQSGRFADEIIPVSIPQRKGDPLVFDTDEFPRPGTTAETLGRLRPAFDKQGTVTAGNASGINDGAAMVVVMKESKAKELGLTPMARLVAFSSAGVDPAIMGTGPIPASTDCLKKAGWAPADLDLVEANEAFAAQAMSVNQEMGWDLSKVNVNGGAIAIGHPIGASGARVLVTLLYEMQKRDAKKGLATLCIGGGQGVALAVERL

phaA

Acetyl-CoA acetyltransferase

394 amino acids

Belongs to the thiolase-like superfamily. Thiolase family.

41.129 kDa

MNENIVIVDAGRSAIGTFSGSLSSLSATEIGTAVLKGLLARTGLAPEQIDEVILGQVLTAGVGQNPARQTTLKAGLPHSVPAMTINKVCGSGLKAVHLAMQAIACGDADIVIAGGQESMSQSSHVLPRSRDGQRMGDWSMKDTMIVDGLWDAFNNYHMGTTAENIAQKYGFTREQQDAFAAASQQKTEAAQKAGRFQDEIIPIEIPQRKGDPKVFDADEFPRHGTTAESLGKLRPAFSRDGSVTAGNASGINDGAAMVVVMKESKAKELGLKPMARLVAFASAGVDPAIMGTGPIPASTKCLEKAGWTPADLDLIEANEAFAAQAMSVNQDMGWDLSKVNVNGGAIAIGHPIGASGARVLVTLLYEMQKRDAKKGLATLCIGGGQGVALAVERM

phaA

Acetyl-CoA acetyltransferase

393 amino acids

Belongs to the thiolase-like superfamily. Thiolase family.

40.851 kDa

MSNPSIVIASAARTAVGSFNGAFGNTLAHELGAAAIKAVLERAGVEAGEVDEVILGQVLPAGEGQNPARQAAMKAGLPQEKTAWGMNQLCGSGLRAVALGMQQIATGDAKVIVAGGMESMSMAPHCAHLRGGVKMGDYKMIDTMIKDGLTDAFYGYHMGITAENVARKWQLTREEQDEFALASQNKAEAAQKAGRFADEIVPFVVKTRKGDVNVDQDEYIRHGATLDSIAKLRPAFDKEGTVTAGNASGLNDGAAAALLMTEAEAARRGIQPLARIVSWATAGVDPQIMGTGPIPASRKALEKAGWSVADIELVEANEAFAAQACAVNKDLGWDPSIVNVNGGAIAIGHPIGASGARVLNTLLFEMKRRGVSKGLATLCIGGGMGVAMCVERL

phaA

Acetyl-CoA acetyltransferase

393 amino acids

Catalyzes the condensation of two acetyl-coA units to form acetoacetyl-CoA (PubMed:4198758). Is involved in the biosynthesis of polyhydroxybutyrate (PHB), which is accumulated as an intracellular energy reserve material when cells grow under conditions of nutrient limitation (PubMed:2670936, PubMed:4198758). Also catalyzes the reverse reaction, i.e. the cleavage of acetoacetyl-CoA, and is therefore also involved in the reutilization of PHB (PubMed:4198758, PubMed:25152395).

Belongs to the thiolase-like superfamily. Thiolase family.

40.549 kDa

MTDVVIVSAARTAVGKFGGSLAKIPAPELGAVVIKAALERAGVKPEQVSEVIMGQVLTAGSGQNPARQAAIKAGLPAMVPAMTINKVCGSGLKAVMLAANAIMAGDAEIVVAGGQENMSAAPHVLPGSRDGFRMGDAKLVDTMIVDGLWDVYNQYHMGITAENVAKEYGITREAQDEFAVGSQNKAEAAQKAGKFDEEIVPVLIPQRKGDPVAFKTDEFVRQGATLDSMSGLKPAFDKAGTVTAANASGLNDGAAAVVVMSAAKAKELGLTPLATIKSYANAGVDPKVMGMGPVPASKRALSRAEWTPQDLDLMEINEAFAAQALAVHQQMGWDTSKVNVNGGAIAIGHPIGASGCRILVTLLHEMKRRDAKKGLASLCIGGGMGVALAVERK

phaA

Acetyl-CoA acetyltransferase

392 amino acids

Belongs to the thiolase-like superfamily. Thiolase family.

40.473 kDa

MSTPSIVIASARTAVGSFNGAFANTPAHELGATVISAVLERAGVAAGEVNEVILGQVLPAGEGQNPARQAAMKAGVPQEATAWGMNQLCGSGLRAVALGMQQIATGDASIIVAGGMESMSMAPHCAHLAGGVKMGDFKMIDTMIKDGLTDAFYGYHMGTTAENVAKQWQLSRDEQDAFAVASQNKAEAAQKDGRFKDEIVPFIVKGRKGDITVDADEYIRHGATLDSMAKLRPAFDKEGTVTAGNASGLNDGAAAALLMSEAEASRRGIQPLGRIVSWATVGVDPKVMGTGPIPASRKALERAGWKIGDLDLVEANEAFAAQACAVNKDLGWDPSIVNVNGGAIAIGHPIGASGARILNTLLFEMKRRGARKGLATLCIGGGMGVAMCIESL

phaA

Acetyl-CoA acetyltransferase

392 amino acids

Involved in the production of polyhydroxyalkonic acids (PHAs), composed primarily of 3-hydroxybutyric acid (3HB) and 3-hydroxyvaleric acid (3HV).

Belongs to the thiolase-like superfamily. Thiolase family.

40.119 kDa

MEVAIVAAQRTAIGSFGGGLAKIPAPELGATVIKALLEKTGVKPEDVSEVILGQVLTAGSGQNPARQALIKAGLPVTTPATTLNVVCGSGLRAVHLAAQAILAGDADIVIAGGQESMSLSPHILPGSRDGFRMGNAQLVDTMVNDGLTDAYNAYHMGITAENVAAKYGIGREEQDAFSLQSQQRAAAAQKAGKFRDEIVPVLVPQRKGDPLAFDADEFIKHDASADGLAKLRPAFKKDGTVTAGNASGINDGAAAVLLMSTQKADQLGLKPLAIIKGYALTGCEPEIMGIGPVSATRKALSKAGWTVEDLDLVEANEAFAAQALGVAKELGWGSDKVNVNGGAIALGHPIGASGCRVLVTLLHEMQRRGAKKGLATLCIGGGMGVALAVERP

phaA

Acetyl-CoA acetyltransferase

391 amino acids

Belongs to the thiolase-like superfamily. Thiolase family.

40.745 kDa

MTKAVIVSAARTPVGSFLGSFANLPAHELGAIVLKAVVERAGIDPSEVSETILGQVLTAAQGQNPARQAHIKVGLPRESAAWVINQVCGSGLRTVALAAQQVLLGDARIVVAGGQESMSLAPHAAYIAPGQKMGDMKMLDTMIKDGLWDAFNDYHMGTTAENVAGKWEISRAEQDQFAVASQNKAEAAQKAGKFADEIVPVTIKSRKGETVVDADEYIRHGATLEAMENVRPAFSKEGTVTAGNASGLNDGAAAVLVMTEDEAARRGLTPLARIASYATAGVDPQIMGTGPIPASRKALEKAGWSVGDLDLVEANEAFAAQAIAVNRDMGWDPSIVNVNGGAIAIGHPIGASGCRILNTLLFEMQRRDAKKGLATLCIGGGMGVALCLERP