pgbA

Plasminogen-binding protein PgbA

452 amino acids

Binds plasminogen, specifically, and in a concentration and lysine-dependent manner. Plasminogen is the precursor of plasmin, a serine protease that cleaves fibrin, fibronectin, laminin and vitronectin. Acquisition of plasminogen/plasmin could enable H.pylori to degrade host components.

52.656 kDa

MLRLLIGLLLMSFISLQSASWQEPLRVSIEFVDLPKKIIRFPAHDLQVGEFGFVVTKLSDYEIVNSEVVIIAVENGVATAKFRAFESMKQRHLPTPRMVARKGDLVYFRQFNNQAFLIAPNDELYEQIRATNTDINFISSDLLVTFLNGFDPKIANLRKACNVYSVGVIYIVTTNTLNILSCESFEILEKRELDTSGVTKTSTPFFSRVEGIDAGTLGKLFSGSQSKNYFAYYDALVKKEKRKEVRIKKREEKIDSREIKREIKQEAIKEPKKANQGTQNAPTLEEKNYQKAERKLDAKEERRYLRDERKKAKATKKAMEFEEREKEHDERDEQETEGRRKALEMDKGDKKEERVKPKENEREIKQEAIKEPSDGNNATQQGEKQNAPKENNAQKEENKPNSKEEKRRLKEEKKKAKAEQRAREFEQRAREHQERDEKELEERRKALEAGKK

pgbA

Plasminogen-binding protein PgbA

450 amino acids

Binds plasminogen, specifically, and in a concentration and lysine-dependent manner. Plasminogen is the precursor of plasmin, a serine protease that cleaves fibrin, fibronectin, laminin and vitronectin. Acquisition of plasminogen/plasmin could enable H.pylori to degrade host components (By similarity).

52.221 kDa

MLRLLIGLLLMSFISLQSASWQEPLRVSIEFVDLPKKIIRFPAHDLKVGEFGFVVTKLSDYEIVNSEVVIIAVENGVATAKFKAFESMKQSHLPTPRMVAKKGDLVYFRQFNNQAFLIAPNDELYEQIRATNTDINFISSDLLVTFLNGFDPKIANLRKACNVYSVGVIYIVTTNTLNILSCESFEILEKRELDTSGVTKTSTPFFSRVEGIDAGTLGKLFSGSQSKNYFAYYDALVKKEKRKEVRIEKKEERIDARENKREIKQEAIKEPKKANQGTENAPTLEEKNYQKAERKFDAKEERRRSRDERKKTKATKKAMEFEEREKEHDERDEKETEERRKALEMDKGNEKVNAKENEREINQESANEPSSENNATLKDTENTSVLKESAAKKEAPKPSSKEEKRRLKEEKKKAKAEQRAREFEQRAREHQERDEKELEERRKALEMNKK