Pgam5

Serine/threonine-protein phosphatase Pgam5, mitochondrial

291 amino acids

Displays phosphatase activity for serine/threonine residues, and dephosphorylates and activates Pk92B kinase. Has apparently no phosphoglycerate mutase activity (By similarity).

Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

33.513 kDa

MRKFTAFACGTGAGLAAFYLQRLRDPKQTAWVHNSWTNSERPVDSWALWDSNWDCRDPKSLVRPQKNEQPQEQNRYNSDFEKNHAKSARHIILIRHGEYLDVGDTDDTHHLTERGREQAKFTGQRLHDLGIKWDKVIASTMVRAQETADIILNEIDYDKAKVTNCAYLREGAPIPPQPPVGHWKPEASQFFRDGARIEAAFRRYFHRAYPDQTKESYTLIVGHGNVIRYFVCRALQFPPEAWLRISINHASITWLTISPSGNVSIKYLGDSGFMPVKHLTNRIPRDAKNVV

pgam5

Serine/threonine-protein phosphatase PGAM5, mitochondrial

289 amino acids

Displays phosphatase activity for serine/threonine residues. Has apparently no phosphoglycerate mutase activity. May be regulator of mitochondrial dynamics (By similarity). May be a central mediator for programmed necrosis (By similarity).

Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

32.173 kDa

MSFRRALSLACGFAGGSAVLVCAAVVADKNGYFGEGRRVTETLAAVNAAHPPAWPTANGWDYNWDKREPSSMVNGKRKESTGENGSQDAENNKPRATRHIFLIRHSQYNLKGDGDKERFLTPLGREQAEFTGQRLASFGLKYDTLIHSSMTRATETANIISKYLPGVELVSCDLLREGAPIEPVPPVTHWKPEAVQYHEDGARIEAAFRRYIHRADAKQKEDSYEIIVCHANVIRYFVCRALQFPPEGWLRLGLNNGSITWLTVRPSGRVSLRALGDSGFMPPDKLTRT

Pgam5

Serine/threonine-protein phosphatase Pgam5, mitochondrial

289 amino acids

Displays phosphatase activity for serine/threonine residues, and dephosphorylates and activates Pk92B kinase. Has apparently no phosphoglycerate mutase activity (By similarity).

Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

32.959 kDa

MRKLSSLVCGAGAGLAAFYLSRLRDPQKAAHSSWTNSEKPVDACGLWDSNWDCRDPRLMVRPLKNTQPEEENRFNADLEKAKPKKARHIILVRHGEYLDVGESDATHHLTERGRKQAQFTGQRLSELGIQWDKVIASTMVRAQETADIILKEIKYDKEKVVNCVYLREGAPIPPQPPVGHWKPEASQFYRDGARIEAAFRRYFHRAYPDQDKESYTLIVGHGNVIRYFVCRALQFPPEGWLRISINHASITWLTISPSGNVSIKYLGDSGFMPVQYLTNRIPRDAKNVV

Pgam5

Serine/threonine-protein phosphatase Pgam5, mitochondrial

289 amino acids

Displays phosphatase activity for serine/threonine residues, and dephosphorylates and activates Pk92B kinase. Has apparently no phosphoglycerate mutase activity (By similarity).

Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

33.151 kDa

MRKLTSFVCGTGAGLAVYYLQRLRDPQATVNNSWTNSEKPVDPWALWDTNWDCREPRALVRPLRNSQPEEENRYNAELEKAKAKKARHIILVRHGEYLDVGDSDDTHHLTERGRKQAEFTGKRLCELGIKWDKVVASTMVRAQETSDIILKQIDFEKEKVVNCAFLREGAPIPPQPPVGHWKPEASQFLRDGSRIEAAFRRYFYRAYPDQEKESYTLIVGHGNVIRYFVCRALQFPAEGWLRISINHASITWLTISPSGNVSIKYLGDSGFMPAELLTHRIPRDAKNVV

Pgam5

Serine/threonine-protein phosphatase Pgam5, mitochondrial

289 amino acids

Displays phosphatase activity for serine/threonine residues, and dephosphorylates and activates Pk92B kinase. Has apparently no phosphoglycerate mutase activity (By similarity).

Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

33.166 kDa

MRKFTAFACGTIAGLSAYYIQRLNDPQLRVHNSWTNSETPISDCALWNSNWDFRDPKSLVRPLKNDNPQEQNRYNSELEKHVPKKARHIILIRHGEYLDVGDTDDSHHLTDRGRQQAKYTGQRLHELGITWDKVIASNMVRAQETADIILNEIDYDKANVKNCPFLREGAPIPPQPPVGHWKPEGSQFFRDGARIEAAFRRYFHRAYPEQEKESYTLIVGHGNVIRYFVCRALQFPAEAWLRISINHASITWLTISASGNVSIKYLGDSGFLPAKLLTNRIPRDAKNVV

Pgam5

Serine/threonine-protein phosphatase Pgam5, mitochondrial

289 amino acids

Displays phosphatase activity for serine/threonine residues, and dephosphorylates and activates Pk92B kinase. Has apparently no phosphoglycerate mutase activity.

Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

33.166 kDa

MRKLTSFVCGTGAGLAAYYLQRLRDPQTVVQNSWTHSDKPVDPWALWDTNWDCREPRALVRPLRNSQPEEENRYNAELEKAKAKKARHIILVRHGEYLDVGDSDDTHHLTERGRKQAEFTGKRLCELGIKWDKVVASTMVRAQETSDIILKQIDFEKEKVVNCAFLREGAPIPPQPPVGHWKPEASQFLRDGSRIEAGFRRYFHRAYPDQEKESYTLIVGHGNVIRYFVCRALQFPAEGWLRININHASITWLTISPSGNVSIKYLGDSGFMPAELLTNRIPRDVKNVV

Pgam5

Serine/threonine-protein phosphatase Pgam5, mitochondrial

289 amino acids

Displays phosphatase activity for serine/threonine residues, and dephosphorylates and activates Pk92B kinase. Has apparently no phosphoglycerate mutase activity (By similarity).

Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

33.293 kDa

MRKFAAFACGTGAGFAAYYFQKLRDPLQVVHNSWTNSERHISECALWDSNWDYRDPKSLARPMKNDKPQEQNRYNADLEKNVSKYARHIILIRHGEYLDVGETDETHHLTDRGRLQAKYTGKRLHELGIKWDKVIASNMVRAQETAEIILNEIDFDKTKVKSCSYLREGAPIPPQPPVGHWKPEASQFFRDGARIEAAFRRYFHRALPDQEKDSYTLIVGHGNVIRYFVCRALQFPAEGWLRININHASITWLTISPSGNVSIKYLGDTGFIPAKHLTNRIPREAKNVV

Pgam5

Serine/threonine-protein phosphatase Pgam5, mitochondrial

289 amino acids

Displays phosphatase activity for serine/threonine residues, and dephosphorylates and activates Pk92B kinase. Has apparently no phosphoglycerate mutase activity (By similarity).

Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

33.113 kDa

MRKFTAFACGTGAGLLTFYLTKLNEPKAAVHNSWTRSEKPVDPCALWDHNWDLRDPKSLVKPVKNDLSQEQNRYNTELEKVVPKHARHIILIRHGEYLDVGDTDETHHLTERGREQAKYTGKRLCELGIKWDKVIASTMVRAQETADIILNEIDYEKTKVKNCAFLREGAPIPPQPPVGHWKPEASQFFRDGARIEAAFRRYFYRAYPDQTKDSYTLLVGHGNVIRYFVCRALQFPPEAWLRISINHASITWLTISPSGNVSIKYLGDTGFMPVNHLTNRIPRAAKNVV

Pgam5

Serine/threonine-protein phosphatase Pgam5, mitochondrial

289 amino acids

Displays phosphatase activity for serine/threonine residues, and dephosphorylates and activates Pk92B kinase. Has apparently no phosphoglycerate mutase activity (By similarity).

Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

33.069 kDa

MRKFTAFACGTGAGLLTFYLTKLNEPKAAVHNSWTRSEKPVDPCALWDHNWDLRDPKSLVKPVKNDLSQEQNRYNSELEKVVPKHARHIILIRHGEYLDVGDTDETHHLTERGREQAKYTGKRLCELGIKWDKVIASTMVRAQETADIILNEIDYEKAKVKNCAFLREGAPIPPQPPVGHWKPEASQFFRDGARIEAAFRRYFYRAYPDQTKDSYTLLVGHGNVIRYFVCRALQFPPEAWLRISINHASITWLTISPSGNVSIKYLGDTGFMPVNHLTNRIPRAAKNVV

Pgam5

Serine/threonine-protein phosphatase Pgam5, mitochondrial

289 amino acids

Displays phosphatase activity for serine/threonine residues, and dephosphorylates and activates Pk92B kinase. Has apparently no phosphoglycerate mutase activity (By similarity).

Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

33.142 kDa

MRKLTSFACGTGAGLAAYYLQRLRDPQTAVQNSWTHSDKPVDPWALWDTNWDCREPRALVRPLRNSQPEEENRYNAELEKAKAKKARHIILVRHGEYLDVGDSDDTHHLTERGRKQAEFTGKRLCELGIKWDKVVASTMMRAQETSDIILKQIDFEKEKVVNCAFLREGAPIPPQPPVGHWKPEASQFLRDGSRIEAGFRRYFHRAYPDQEKESYTLIVGHGNVIRYFVCRALQFPAEGWLRININHASITWLTISPSGNVSIKYLGDSGFMPAELLTNRIPRDVKNVV

Pgam5

Serine/threonine-protein phosphatase Pgam5, mitochondrial

289 amino acids

Displays phosphatase activity for serine/threonine residues, and dephosphorylates and activates Pk92B kinase. Has apparently no phosphoglycerate mutase activity (By similarity).

Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

33.124 kDa

MRKLTSFACGTGAGLAAYYLQRLRDPQTAVQNSWTHSDKPVDPWALWDTNWDCREPRALVRPLRNSQPEEENRYNAELEKAKAKKARHIILVRHGEYLDVGDSDDTHHLTERGRKQAEFTGKRLCELGIKWDKVVASTMLRAQETSDIILKQIDFEKEKVVNCAFLREGAPIPPQPPVGHWKPEASQFLRDGSRIEAGFRRYFHRAYPDQEKESYTLIVGHGNVIRYFVCRALQFPAEGWLRININHASITWLTISPSGNVSIKYLGDSGFMPAELLTNRIPRDVKNVV

Pgam5

Serine/threonine-protein phosphatase Pgam5, mitochondrial

289 amino acids

Displays phosphatase activity for serine/threonine residues, and dephosphorylates and activates Pk92B kinase. Has apparently no phosphoglycerate mutase activity (By similarity).

Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

33.194 kDa

MRKFTAFACGTGAGLAAYYLQKLRDPQLAVHNSWTNSDRPISECALWDSNWDFRDPKSLVRPQKNDLPQEQNRYNSDLEKHVAKSARHIILIRHGEYLDVGDSDDTHHLTDRGRLQAKYTGQRLRELGIKWDKVIASNMVRAQETADIILNQIDYDKAKLKHCSYLREGAPIPPQPPVGHWKPEASQFFRDGARIEAAFRRYFHRALPEQEKESYTLIVGHGNVIRYFVCRALQFPAEAWLRISINHASITWLTISPSGNVSIKYLGDTGFMPAKYLTHRIPRDAKNVV

Pgam5

Serine/threonine-protein phosphatase Pgam5, mitochondrial

289 amino acids

Displays phosphatase activity for serine/threonine residues, and dephosphorylates and activates Pk92B kinase. Has apparently no phosphoglycerate mutase activity (By similarity).

Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

33.139 kDa

MRKLTSFVCGTGAGFAAYYLQRLRDPQAAVHNSWTNSDKPVDPWALWDTNWDCREPRALVRPLRNSQPEEENRYNAELEKAKAKKARHIILVRHGEYLDVGDSDDTHHLTDRGRKQAEFTGKRLSELGIKWDKIVASTMVRAQETSDIILKQIEFEKEKVVNCAFLREGAPIPPQPPVGHWKPEASQFLRDGSRIEAAFRRYFHRAYPDQEKESYTLIVGHGNVIRYFVCRALQFPAEGWLRISINHASITWLTISPSGNVSIKYLGDSGFMPPELLTNRIPRDVKNVV

PGAM5

Serine/threonine-protein phosphatase PGAM5, mitochondrial

289 amino acids

Displays phosphatase activity for serine/threonine residues, and, dephosphorylates and activates MAP3K5 kinase. Has apparently no phosphoglycerate mutase activity. May be regulator of mitochondrial dynamics. Substrate for a KEAP1-dependent ubiquitin ligase complex. Contributes to the repression of NFE2L2-dependent gene expression. Acts as a central mediator for programmed necrosis induced by TNF, by reactive oxygen species and by calcium ionophore.

Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

32.004 kDa

MAFRQALQLAACGLAGGSAAVLFSAVAVGKPRAGGDAEPRPAEPPAWAGGARPGPGVWDPNWDRREPLSLINVRKRNVESGEEELASKLDHYKAKATRHIFLIRHSQYHVDGSLEKDRTLTPLGREQAELTGLRLASLGLKFNKIVHSSMTRAIETTDIISRHLPGVCKVSTDLLREGAPIEPDPPVSHWKPEAVQYYEDGARIEAAFRNYIHRADARQEEDSYEIFICHANVIRYIVCRALQFPPEGWLRLSLNNGSITHLVIRPNGRVALRTLGDTGFMPPDKITRS

Pgam5

Serine/threonine-protein phosphatase PGAM5, mitochondrial

288 amino acids

Displays phosphatase activity for serine/threonine residues, and, dephosphorylates and activates MAP3K5 kinase. Has apparently no phosphoglycerate mutase activity. May be regulator of mitochondrial dynamics. Substrate for a KEAP1-dependent ubiquitin ligase complex. Contributes to the repression of NFE2L2-dependent gene expression (By similarity). Acts as a central mediator for programmed necrosis induced by TNF, by reactive oxygen species and by calcium ionophore.

Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

31.994 kDa

MAFRQALQLAACGLAGGSAAVLFSAVAVGKPRGGGDADTRATEPPAWTGARAGRGVWDTNWDRREPLSLINLKKRNVESGEDELTSRLDHYKAKATRHIFLIRHSQYHVDGSLEKDRTLTPLGREQAELTGLRLASLGLKFNKIVHSSMTRAVETTDIISKHLPGVSRVSTDLLREGAPIEPDPPVSHWKPEAVQYYEDGARIEAAFRNYIHRADARQEEDSYEIFICHANVIRYIVCRALQFPPEGWLRLSLNNGSITHLVIRPNGRVALRTLGDTGFMPPDKITRS

Pgam5

Serine/threonine-protein phosphatase PGAM5, mitochondrial

288 amino acids

Displays phosphatase activity for serine/threonine residues, and, dephosphorylates and activates MAP3K5 kinase. Has apparently no phosphoglycerate mutase activity. May be regulator of mitochondrial dynamics. Substrate for a KEAP1-dependent ubiquitin ligase complex. Contributes to the repression of NFE2L2-dependent gene expression (By similarity). Acts as a central mediator for programmed necrosis induced by TNF, by reactive oxygen species and by calcium ionophore.

Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

32.06 kDa

MAFRQALQLAACGLAGGSAAVLFSAVAVGKPRAGGDADTRTTEPLAWTGARPGHGVWDSNWDRREPLSLINLKKRNVEFGEDELASRLDHYKAKATRHIFLIRHSQYNVDGSMEKDRTLTPLGREQAELTGIRLASLGLKFNKIVHSSMTRAVETTDIISKHLPGVCRVSTDLLREGAPIEPDPPVSHWKPEAVQYYEDGARIEAAFRNYIHRADAKQEEDSYEIFICHANVIRYIVCRALQFPPEGWLRLSLNNGSITHLVIRPNGRVALRTLGDTGFMPPDKITRS

pgam5

Serine/threonine-protein phosphatase PGAM5, mitochondrial

278 amino acids

Displays phosphatase activity for serine/threonine residues. Has apparently no phosphoglycerate mutase activity. May be regulator of mitochondrial dynamics (By similarity). May be a central mediator for programmed necrosis (By similarity).

Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

31.211 kDa

MYLRKALIAGGSAAAAAAAILGAAAVGKSKGGPDLDILSVVPAATGQWDRNWDRREPISMVNLSKINGETGEEELQLHLNKHKPKATRHIFLIRHSQYKQDGKTDFDRVLTPLGREQADLTGKRLSSLGFKYNHIVYSTMTRAKETTEIISKYLPDVKKSSSDLLREGAPIRPEPQVCHWKPDFVYYEDGSRIEAAFRHFIHRADPKQEADSYEILICHANVIRYIVCRALQLPPEAWLRMFLNNGSISYLVIRPNGNVSLRMLGDSGFMPPEKISRT

pgam5

Serine/threonine-protein phosphatase PGAM5, mitochondrial

275 amino acids

Displays phosphatase activity for serine/threonine residues. Has apparently no phosphoglycerate mutase activity. May be regulator of mitochondrial dynamics (By similarity). May be a central mediator for programmed necrosis (By similarity).

Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

30.986 kDa

MYLRRALIAGGSAAAAILGVVAAGKSKGGSDSEILSVAPPATGQWDRNWDRREPISMVNLSKINAETGEEELQLHLNKHKPKATRHIFLIRHSQYKLDGKTDFDRVLTPLGREQADLTGQRLASLGHKYNHIVYSTMTRAKETTEIISKYLPDVNKSSSDLLREGAPIRPEPQVCHWKPDFVYYEDGPRIEAAFRHFIHRADPKQEEDSYEILICHANVIRYVVCRALQFPPEAWLRISLNNGSITYLVIRPNGNVSIRMLGDSGFMPAEKISRT