pfs-2

Gene

pfs-2

Protein

pre-mRNA 3' end processing protein pfs-2

Organism

Caenorhabditis elegans

Length

820 amino acids

Function

Essential for both cleavage and polyadenylation of pre-mRNA 3' ends (By similarity). Involved in neuron development, probably by regulating pre-mRNA 3'-end processing (PubMed:20530551).

Similarity

Belongs to the WD repeat WDR33 family.

Mass

91.193 kDa

Sequence

MTAVSNIASFNMNGGMMRGNQMPNVTLTIQPSTSSMQNSQPRIMNNHHHPHNRFQREHVMPDVMGDGPGRRLRKNVANVRRHVDYVSTVLNHCENRLWQYGKQRILQQPDILYQQYAVPADSTPDVPVDCILTKFIRTAMNKVKCPVYSVCWSPEGKRLITGCQTGEFTLWNGTAFNFETILQAHDSAIRALKWASNEQWLLSADQGGYVKYWQPNMNNAHMFSAHKDEAIRGLAFAPTDVKFATASDDGTARVWDFARYTEERVLRGHGAEVRCIDWHPTKGLIATGSRDTQQPVKIWDPKSGSCLATLQEHKSSVMAVEFNKNGNWLLTGGRDHLVKMYDIRMMKEMRTYRAHKKEVISLAWHPIHEGLFVSGGGDGSIVYWMVDGEKEIGLLEHAHDQAIWSMKWHPLGHILATGSNDNNTKFWARNRPGDTVEDIFGLSNTNMIGHLDKEREPRMAPPKPSIETQETYRPDTFIPGMGLDEHLYEQLNRDHNMMTTDSTLLVPDDLTRQNFAPMIGAKRTLIKQPPAKKAQRQFERMWNNSKGIGAGSDDFTTMKGGLGREDAEGAQFGPSKSFLGPPTTGGSLLGPSQPRPQEFRSVPPPQQQQGPPPNWRHQGPPMSGPGQGYGPPGRMGGNQGGWQRPPPQGSYGGQGPPQGSYGGQGTLQGSYASQQGPPPRQIQHIPSDIDYRTAPSSSNGSTGDVDMRTMVPNQPPSGEPEHWRGPPPVSHQQQSQQQHPPPINMQRMDPRRDPRMLSGRSDQLSPSGPPPQQQQSSAQQGGKNQWMPQFEAGQNQNQGNYAGNRGGGVGGRGRGRGQPY

Protein

pre-mRNA 3' end processing protein pfs-2: pfs-2