pemtA

Phosphatidylethanolamine N-methyltransferase A

213 amino acids

Catalyzes the three sequential steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME), PMME to phosphatidyldimethylethanolamine (PDME), and PDME to phosphatidylcholine (PC).

Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.

24.515 kDa

MIVEHAIDYIDYLMNYVDFTEKYFLLTIACVVFNPTWWNITARMEYKTKFMTKICGSKENGCYLLAFLIFSLGILRDWLFSEALIRQPIFQEFDRFEVEVLSYILYGFGGILVLAAYLKLGITGTYLGDYFGILMKERVTGFPFNVMNNPMYNGSVMLFIAHALSYKSVAGLVLSFVVYVVYKFALIFEESFTNYIYSTAAANAAKKNKSKSK