pdiA

Gene

pdiA

Protein

Protein disulfide-isomerase

Organism

Aspergillus niger

Length

515 amino acids

Function

Participates in the folding of proteins containing disulfide bonds, may be involved in glycosylation, prolyl hydroxylation and triglyceride transfer.

Similarity

Belongs to the protein disulfide isomerase family.

Mass

56.292 kDa

Sequence

MRSFAPWLVSLLGASAVVAAADTESDVISLDQDTFESFMNEHGLVLAEFFAPWCGHCKALAPKYEEAATELKAKNIPLVKVDCTAEEDLCRSQGVEGYPTLKIFRGVDSSKPYQGARQTESIVSYMIKQSLPAVSSVNEENLEEIKTMDKIVVIGYIPSDDQETYQAFEKYAESQRDNYLFAATDDAAIAKSEGVEQPSIVLYKDFDEKKAVYDGEIEQEAIHSWVKSASTPLVGEIGPETYSGYIGAGVPLAYIFAETKEEREKYTEDFKPIAQKHKGAINIATIDAKMFGAHAGNLNLDSQKFPAFAIQDPAKNAKYPYDQAKELNADEVEKFIQDVLDGKVEPSIKSEPVPESQEGPVTVVVAHSYKDLVIDNDKDVLLEFYAPWCGHCKALAPKYDELAALYADHPDLAAKVTIAKIDATANDVPDPITGFPTLRLYPAGAKDSPIEYSGSRTVEDLANFVKENGKHNVDALNVASEETQEGGDVTEAAPSATEAETPAATDDEKAEHDEL

Protein

Protein disulfide-isomerase: pdiA

Gene

pdiA

Protein

Protein disulfide-isomerase

Organism

Aspergillus oryzae (strain ATCC 42149 / RIB 40)

Length

515 amino acids

Function

Participates in the folding of proteins containing disulfide bonds, may be involved in glycosylation, prolyl hydroxylation and triglyceride transfer.

Similarity

Belongs to the protein disulfide isomerase family.

Mass

56.458 kDa

Sequence

MRTFAPWILSLLGASAVASAADATAEAPSDVVSLTGDTFETFVKEHDLVLAEFFAPWCGHCKALAPKYEQAATELKEKNIPLVKVDCTEEEALCRDQGVEGYPTLKIFRGLDAVKPYQGARQTEAIVSYMVKQSLPAVSPVTPENLEEIKTMDKIVVIGYIASDDQTANDIFTTFAESQRDNYLFAATSDASIAKAEGVKQPSIVLYKDFDEKKATYDGEIEQDALLSWVKTASTPLVGELGPETYSGYITAGIPLAYIFAETKEEREQFTEEFKFIAEKHKGSINIVTIDAKLYGAHAGNLNLDPSKFPAFAIQDPEKNAKYPYDQSKEVKAKDIGKFIQDVLDDKVEPSIKSEAIPETQEGPVTVVVAHSYKDLVLDNEKDVLLEFYAPWCGHCKALAPKYEELASLYKDIPEVTIAKIDATANDVPDSITGFPTIKLFAAGAKDSPVEYEGSRTVEDLANFVKENGKHKVDALEVDPKKEQESGDATETRAASDETETPAATSDDKSEHDEL

Protein

Protein disulfide-isomerase: pdiA

Gene

pdiA

Protein

Cyclic nucleotide phosphodiesterase inhibitor

Organism

Dictyostelium discoideum

Length

237 amino acids

Function

PDI acts by binding stoichiometrically to cyclic nucleotide phosphodiesterase, changing the KM of the enzyme for cAMP from 10 uM to 2 mM.

Mass

25.757 kDa

Sequence

MAKIIISLILLLSLFSFSYGAYNCNKLNCSSKNTKCRTFSCTSVVGCYYTDKCTSPDLCHNSACNASTGNCTLTTISCNDNNPCTDDFCHPGYGCYSVPNSCDPGVICQQNCNDNDPCTYDFCDALNICRHSETYCNDGDACTLNTCGVNGCNFTKISCDDNDPCTADYCSTLYGCYHEPIECSIKVPCNIDSDCNRNNGCETFTCNLSTNTCDYYAKNCGGWPCINNQCTTGSISN

Protein

Cyclic nucleotide phosphodiesterase inhibitor: pdiA

Gene

pdiA

Protein

Cyclic nucleotide phosphodiesterase inhibitor

Organism

Dictyostelium discoideum

Length

237 amino acids

Function

PDI acts by binding stoichiometrically to cyclic nucleotide phosphodiesterase, changing the KM of the enzyme for cAMP from 10 uM to 2 mM.

Mass

25.757 kDa

Sequence

Protein

Cyclic nucleotide phosphodiesterase inhibitor: pdiA