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pdh3

Gene
pdh3
Protein
Pyranose dehydrogenase 3
Organism
Leucoagaricus meleagris
Length
600 amino acids
Function
Catalyzes the single-oxidation or sequential double oxidation reaction of carbohydrates primarily at carbon-2 and/or carbon-3 with the concomitant reduction of the flavin. The enzyme exhibits a broad sugar substrate specificity, oxidizing different aldopyranoses to the corresponding C-1, C-2, C-3 or C-1,2, C-2,3 and C-3,4 (di)dehydro sugars with substrate-specific regioselectivity. Accepts only a narrow range of electron acceptors such as substituted benzoquinones and complexed metal ions and reacts extremely slowly with O(2) as acceptor. May play a role in the natural recycling of plant matter by oxidizing all major monosaccharides in lignocellulose and by reducing quinone compounds or reactive radical species generated during lignin depolymerization (By similarity).
Similarity
Belongs to the GMC oxidoreductase family.
Mass
65.036 kDa
Sequence
MLPRVARLNTHLVSLALLGFQITYGAITYQHPDDLPSDVDYDFIVAGGGTAGLVVASRLSENPDWNILVIEAGPSNKDAPETRVPGLAGSLPASRTDWNYTTIPQDALGGRSLNYSRAKVLGGCSSHNSMVYTRGSKDDWNHWADITGDQGLSWDSILPVMKKAEKFSKDFSNQSVDGHIDPSMHGHDGLLSVVSSYTNVSFNDLLLETTKELSDEFPFKLDLNDGNPHGLAWTQYTIDHRAERSSSATSYLESTRDNVHVLVNSRVTRIFSAGNGTDFRSVEFAVDANSPKKVLTAKKEVILSAGVIASPQVLMNSGIGGREELQAIGVDTLIDNPSVGKNLSDQAATLLMFDTTLPNTDYDVAAALTEWEDSRSGPMAYGARLNHLTWVRLLDDKLNGSDPSSGKNSPHIEFQFMQISHQLPPADAPNQVKLPDPDSIGAVLLLAVVNLYSVSHGSIILNDNDPFANPMIDLNMFGDQKDIAILREGVRSARRMFSSQAFKDVVNGTVYPPADVTSDEDLDAFLRTSAISYWHGVGTLSMSPQNASWGVVDPDFRVKGTSGLRVVDASVIPYAPAGHTQVPVYTFAEHASVLIAKSYA