pde7

Gene

pde7

Protein

cAMP/cGMP-dependent 3',5'-cAMP/cGMP phosphodiesterase 7

Organism

Dictyostelium discoideum

Length

425 amino acids

Function

Phosphodiesterase with dual cAMP/cGMP specificity. However, displays a preference for cAMP over cGMP. Seems to regulate cAMP/cGMP concentration especially during cell aggregation.

Similarity

Belongs to the cAMP phosphodiesterase class-II family.

Mass

48.505 kDa

Sequence

MKYLILILIFFIEINNGSRLINSGNLFSELKDYYIPENLNYYSGGYSEQHCKDSSYITIPLGVTGGLDEGSLSSFLLTKKGSSLFIGLDAGTVWQGVRRLTMLQDFNSVFNITYPPWATLPEQRATWFIKNHIQGYLIGHSHLDHVGGLIVESAEDQLSPKKNELEVSQPEIYRGCIEMIHKMGYVSDFPNITSIPDQKKPIIGINETLYSMATDLFNGFVWPSLPNYGRYSYYYLGNGNQYSFKDLTPYANKYVTKVQNDFPFNHLVKSFEICHDSLTSTAFILTDSQSGEQIVFFSDTGISTTKCDWEFKILQVWRNIKIDKLKAVYIESSFTNEVADNVLFGHLRPKDIMKLMDSLLENSIQTSPPKTNLKHVKLIIEHIKPQVGMNQYYLTSQRMVYQQLQEINNHGVKVIIPNQGVPICL

Protein

cAMP/cGMP-dependent 3',5'-cAMP/cGMP phosphodiesterase 7: pde7