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pcm2

Gene
pcm2
Protein
Protein-L-isoaspartate O-methyltransferase 2
Organism
Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)
Length
306 amino acids
Function
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
Similarity
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
Mass
32.108 kDa
Sequence
MSTTPPRNKFPLPLDAVVERKPAPARTAGLPAVGTPRPAAPTPAPAKPAKPRLPRTAAPAPAPVPASAVEQRASAATAGGGGMASARARAALAARLRAAGIRDERVLSAIATVPRHLFVEPGLASQAYEDAALPIGHQQTISKPSVVARMIELLREGLAADAPLERVLEIGTGCGYQAAVLSQVAREVFSIERIRPLHEQAKANLRPLRVPNLRLHYGDGMLGLPQAAPFSAIILAAAGMEVPEALLEQLAIGGRLIAPVAVMPPAGVPGQTVTQQLLLIERRNRHRFHRTALEAVFFVPLKSGTI

Gene
pcm2
Protein
Protein-L-isoaspartate O-methyltransferase 2
Organism
Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)
Length
247 amino acids
Function
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
Similarity
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
Mass
26.797 kDa
Sequence
MSRKSTGAFLVILLLSMAAGGAVGAADDPYGAARAKMVREIEEDARRTSERIGKTALDPRVMEIMARVPRHEFVPAAERAYAYENRPLPIGYGQTISQPYIVAVMTDLLKVGSESTVLEVGTGSGYQAAILAEFVRSVYSIEIIEALAETAAERLKRLGYDNVRVRTGDGYHGWKEHAPFDGIVVTAAAGHIPPPLLDQLKPGGRMIIPVGGPFFVQQLMLVEKDEQGRTRTRQILPVAFVPLTGGH

Gene
pcm2
Protein
Protein-L-isoaspartate O-methyltransferase 2
Organism
Shewanella sediminis (strain HAW-EB3)
Length
244 amino acids
Function
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
Similarity
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
Mass
26.988 kDa
Sequence
MGKLLFLFITLILFEQQSLAALPTGDSEKYLRARESMVQNQLSTRDIKDKRVLTAMREVPRHLFVPDLLVFKAYTDSPLPIGEGQTISQPYIVALMTELLELTGSERVLEIGTGSGYQAAVLSQVAKEVFTIEIKEKLCTKAGKLLDSLGYTNIQARCGDGYFGWNKEAPFDAIMITAAVDHVPPPLLAQLKDGGRLVLPLGNPFSYQNLVLVTRKGDDYRVWQISGVLFVPMTGHALKDSGEK

Gene
pcm2
Protein
Protein-L-isoaspartate O-methyltransferase 2
Organism
Anaeromyxobacter sp. (strain Fw109-5)
Length
243 amino acids
Function
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
Similarity
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
Mass
26.454 kDa
Sequence
MLARSLLPALALLLAATAGGDACADRGHPSAERSTPETERRRMVEEQLAARGIRDRRVLEAMGKVPRERFVPEQWRSLAYLDEPLPIGRGQTISQPYVVAFMAQALALRGGERVLEVGSGSGYAAAVLAHLAGAVYGIELEPELHARSVETLAELGYGNVHLRRGDGFLGWPERAPFRAIVVSCAMEEIPAPLWEQLVQGGRIVYPKGPEGEVQLLVVVTKTARGPREEHLAPVRFVPMRRGG

Gene
pcm2
Protein
Protein-L-isoaspartate O-methyltransferase 2
Organism
Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)
Length
238 amino acids
Function
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins (By similarity).
Similarity
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
Mass
26.97 kDa
Sequence
MVLVNAISEKDYIKDSRRRKKEEKEFEKLRKLLVEGLEDIVRDKKVLKAMFRVPRHRFVPEYEQRAAYTDRPLEIGHGQTISTPHTVALMCEILELSEGHKVLEIGTGSGYNAAVMAELVGKTGHIYSVERIEPLVNFARKNLEQMGYDNVTVLLENGSMGYPRYAPYDRIAVTCAAPTIPKALLEQLKPGGIMVIPVGDYSQELIRVKKDSNGNIYKKRKGEVIFVPMLGRHGFPRS

Gene
pcm2
Protein
Probable protein-L-isoaspartate O-methyltransferase
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Length
230 amino acids
Function
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins. This enzyme does not act on D-aspartyl residues (By similarity).
Similarity
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
Mass
25.333 kDa
Sequence
MFWSFNLSSNAALVQHLVESKFLTNQRAIKAMNATSRSFYCPLSPYMDSPQSIGYGVTISAPHMHATALQELEPVLQPGCSALDIGSGSGYLVAAMARMVAPNGTVKGIEHIPQLVETSKKNLLKDINHDEVLMEMYKEKRLQINVGDGRMGTSEDEKFDAIHVGASASELPQKLVDQLKSPGKILIPIGTYSQNIYLIEKNEQGKISKRTLFPVRYVPLTDSPDDSSDY

Gene
pcm2
Protein
Protein-L-isoaspartate O-methyltransferase 2
Organism
Pelobacter propionicus (strain DSM 2379 / NBRC 103807 / OttBd1)
Length
225 amino acids
Function
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
Similarity
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
Mass
25.003 kDa
Sequence
MRYRCPMNCPSLRNQEYRREIMISEQLMGRGIRDPAVLAAMRQVPREAFVDQGMRELAYEDHPLPIDGGQTISQPYIVAYMTEALELSSSDRVLEIGTGSGYAAAVLSRIVHTVYSVERLEELARGARQRLESLGYNNVEVFEGDGTLGWPEHAPYDAIVVTAGAPAVPKPLLRQLVVGGRLVIPVGASSFLQNLIRVRRQGEDDYRSEELCGVRFVPLVGAEGW

Gene
pcm2
Protein
Protein-L-isoaspartate O-methyltransferase 2
Organism
Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Length
219 amino acids
Function
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins (By similarity).
Similarity
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
Mass
24.667 kDa
Sequence
MDYDEKRERLAERLRQELNLSRKVYEAIRKVPRHLFVPESYKNEAYVDTPLPIGYGQTISAPHMVAIMCELLDLREGDKVLEVGTGCGYHAAVTAEIVGKSGKVISIEYIPELAERARAILKALGYDNVEVIVGDGSKGYEKEAPYDKIYVTAAAPDIPKPLIEQLKPRGRMVIPVGDSVQWLIIVEKDESGNVRKKNWGSVRFVPLRGEYGFKSVRYD

Gene
pcm2
Protein
Protein-L-isoaspartate O-methyltransferase 2
Organism
Marinobacter hydrocarbonoclasticus (strain ATCC 700491 / DSM 11845 / VT8)
Length
219 amino acids
Function
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
Similarity
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
Mass
23.65 kDa
Sequence
MNKDGQDLSDIRRAMVRCQLVPRGISDGRVLEAMERVPREQFVPEHLRFEAYEDHPVPIGQGQTISQPYIVALMAEALCLKGRERVLDIGTGSGYAAAVLASLALEVFSIERIPELAAQARKNLDRTGFTQVHVKCADGTLGWPEAAPFDGICVAAGAPAVPAALKQQLAVGGRLVIPVGTEGGLQQLLCITRLSDSEYEQASYGDVRFVPLLGEEGWP

Gene
pcm2
Protein
Protein-L-isoaspartate O-methyltransferase 2
Organism
Nitrosococcus oceani (strain ATCC 19707 / BCRC 17464 / NCIMB 11848 / C-107)
Length
219 amino acids
Function
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
Similarity
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
Mass
24.264 kDa
Sequence
MKSHREMLRGIQREAGITQRWIGKESLDRRVMEAMKAVPRHEFVPDEQRPYAYDDAPLAIGCGQTISQPYIVALMTDLLDSTPDDIILEVGTGSGYQAAVLSRLVKKVYTIETIEELAQQAEARLERLGYSNVEVQTADGYFGWPEQAPFDGIMVTAAAPSIPKPLIDQLKPEARLVLPLGAGSPQELMVVTKKENDEIDIHRVLGVSFVPLTGKHEVP

Gene
pcm2
Protein
Protein-L-isoaspartate O-methyltransferase 2
Organism
Geobacter uraniireducens (strain Rf4)
Length
217 amino acids
Function
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
Similarity
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
Mass
23.637 kDa
Sequence
MINLDIARRRMVENQIVARGIKDRRVIDAMLKVPRHIFVEEAMSAQAYSDSSLPIGEKQTISQPYMVALMSGMLQLTGKEKVLELGTGSGYQAAILAELADRVYTVERIRPLALRARKALDSLGYLNVNLKIGDGTDGWASEAPFDAILVTAGAPDVPMHLIDQLAVGGKLVIPVGNQSEQTLVRITKGENGAVSREDSIGCRFVKLIGRYGWSGED

Gene
pcm2
Protein
Protein-L-isoaspartate O-methyltransferase 2
Organism
Rhodopseudomonas palustris (strain HaA2)
Length
217 amino acids
Function
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
Similarity
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
Mass
23.904 kDa
Sequence
MISSVAPPPEKMLFQLSLRRRGISDRGVLQAMESVPRDRFVDAVHRDSAWRDTALPIACGQTISQPFVVAYMTEQLHLQPGHRVLEIGTGSGYHAAVLSRLVRDVVSVERFKTLADRARARLKELNYANVEVVLGDGFALPEGQGTFDRILVTAAMAELPQPLLDLLDPDGILIAPIGPGNGRQTLIRVQRKDDGFLRKPLVDVRFVPALPGIAREL

Gene
pcm2
Protein
Protein-L-isoaspartate O-methyltransferase 2
Organism
Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849 / C 71)
Length
211 amino acids
Function
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
Similarity
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
Mass
23.485 kDa
Sequence
MTSQRTRARMVERLCTQGVTDEAVLTAMITVPRHIFVEEVLASRAYDDVALPINFEQTISNPFTVARMSQLLRAGSNPGKVLEIGTGSGYQTAILAQFSREVYSVERIGPLLTRTRGRLRELRINNVRLKHADGLLGLSEAAPFDGIILTAATPHMPPALLEQLAIRGRMVFPRGTSEQVLCVIERNLQGYTETILDEVKFVPMIPGIWQR

Gene
pcm2
Protein
Protein-L-isoaspartate O-methyltransferase 2
Organism
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length
211 amino acids
Function
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
Similarity
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
Mass
23.226 kDa
Sequence
MMEEITALVRETRTETGKPALDERVMAVMGKVPRHEFVPADQLPRAYQNRPLPIGHGQTISQPYIVALMTDLARVEPGHKVLEVGTGSGYQAAVMAHLARAVYTIEIIEPLGLQARQRLQKLGYDNVQVRLGDGYHGWEEHAPYDAILVTAAASHIPPPLIRQLKAGGRMVIPVGAAFMVQQLMLVEKNRDGTVSTRQILPVAFVPLTGQR

Gene
PCM2
Protein
Calmodulin-2/4
Organism
Solanum tuberosum
Length
124 amino acids
Function
Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.
Similarity
Belongs to the calmodulin family.
Mass
13.986 kDa
Fragment
single
Sequence
GCITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLNLMARKMKDTDSEEELKEAFRVFDKDQNGFISAAELRHVMTNLGEKLTDEEVDEMIREADVDGDGQINYDEFVKVMMAK