Protein
Guanine/hypoxanthine permease PbuO
Organism
Bacillus subtilis (strain 168)
Function
Involved in the uptake of the purine bases hypoxanthine and guanine. May work at purine concentrations higher than 100 uM.
Similarity
Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily.
Sequence
MFHLKEQQTSIKQEIIAGLTTFFTMVYIVVVNPVILANAGVPFDQVFTATIIASIVGTLWMALAANYPIAIAPGMGLNAYLAFHVVSASDGGITYATAFSAVFTAGVLFIILSLTPLRKQLIEAIPNNLKYGITTGIGLFIAFIGLRQAGIVAADESNLVTLGNLHSPGVILTLVGLLISVVLMVLNVSGALFIGMAATALIAFFTGQLHFSKGFMSLPHLPEGLMISNPFTAFGDVIHHGLYAVVFSFLLVTIFDTTGTMIGVAEQAGLMKNNKLPNVRKALLADSTATTVGAVFGTSPTTAFIESSAGVAAGGRTGLTALTVAVMFAASMFFSPLVSALSGIAAITSPALIIVGSLMMGSVSNMNWKEMDEAFPAFLVILAMPLTSSISTGIALGFISYPIVKAARGKWREIHPLVIVFAILFFIQLFIL