pax2a

Paired box protein Pax-2a

410 amino acids

Probable transcription factor involved in the development of the midbrain/hindbrain boundary (MHB) organizer and specification of neuronal cell fates. Required for establishment of eng2 and eng3 gene expression in the midbrain and MHB primordium during late gastrulation.

44.099 kDa

MDIHCKADPFSAMHLSHIGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIRTKVQQPFHPSSDGTGTPLSTAGHTIVPSTASPPVSSASNDPVGSYSINGILGIPRSNGEKRKRDDVLWSGNHLDGRKIGYHGSDGSGPNSDSQGSVESLRKHLRADAFTQQQLEALDRVFERPSYPDVFPTSEHIKPEQANEYSLPALNPGLDEVKPSLSTSVSSDLGSSVSQSYPVVTGREMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSDFSGNPYSHPQYTTYNEAWRFSNPALLSSPYYYSAASRGSGPPTAATAYDRH