papola-a

Gene

papola-a

Protein

Poly(A) polymerase alpha-A

Organism

Xenopus laevis

Length

715 amino acids

Function

Polymerase that creates the 3'-poly(A) tail of mRNA's. May acquire specificity through interaction with a cleavage and polyadenylation factor (CPSF).

Similarity

Belongs to the poly(A) polymerase family.

Mass

80.188 kDa

Fragment

single

Sequence

PKTFGITSPISLAAAKDTDCTLMQKLIETLKPYGVFEEEEQLQHRILGKLNNLVKEWIREISELKHLPQSVIENVGGKIFTFGPYRLGVHTKGADIDALCVAPRHVDRSDFFSSFYDKLKQQEEVKDLRSVEEAFVPVIKLCFDGIEIDILFARLALQTIPEDLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDSFRLTLRAIKLWAKRHNIYSNILGFLGGVSWAMLVARTCQLYPNAIASTLVHKFFLVFSKWEWPNPVLLKQPEECNLNLPVWDPRVNPSDRYHLMPIITPAYPQQNSTYNVSVSTRAVMIEEFKQGLAITDEILLGKAEWSKLFDAPNFFQKYKHYILLLASAPTEKQRLEWVGLVESKIRILVGSLEKNEFITLAHVNPRSFPAPSENMEKEEFRTMWVIGLVFKKMENSENLSVDLTYDIQSFTDTVDRQAINSKMFETEMKIAAMHVKRKQLHQLQPSHVSPKKKKHSFEGVKLLSLNDSSIDLSVDSDNSMSVPSPTNATRTSPLNSSGLSQGNSPAAPVSFSVTNVQATDVMVPQNNSTENLGGSLNESIPESATHPGFSSTPKPLVTRVVSSMRLVNQLQKPVSNTITKMPSPVAGVKRTSSPSNEDSPKKNKTEEDENDSSISADVDDQNKLETEELKEVHSEEKSSSPVPGSLPFSQQSSTDLSDISVVPATPIPVIKNSIKLRLNR

Protein

Poly(A) polymerase alpha-A: papola-a