Protein
3-methyl-2-oxobutanoate hydroxymethyltransferase
Organism
Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
Function
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
Similarity
Belongs to the PanB family.
Sequence
MASPARVKRSLPDLTHPELTSSGAPLVMVTAYDYPGARHAEAAGVDLILVGDSLGNVVLGYDSTAPVTLADMIHHGKAVRRGAPNTFLVVDLPFGTYHAGVTDAMRHAVRVIQETGADAVKMEGSTPEVLDVVRVLSRNGVPVMGHVGLMPQTAAAQGGLRVQGKDDDSARRTLEGAVALQEAGAFAVVLEAIPARLARLISERLSVATIGIGAGVHCDGQVLVYHDLLGLYEGEEKKIAKRYADLGREAREAIAHYAAEVRAREFPSKDNSFVMKDEVLDKLY