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oxa101

Gene
oxa101
Protein
Mitochondrial inner membrane protein oxa1-1
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Length
374 amino acids
Function
Required for the insertion of integral membrane proteins into the mitochondrial inner membrane. Essential for the activity and assembly of cytochrome c oxidase. Not essential for viability, while oxa102 is essential. When both genes are deleted the cell is non-viable, suggesting that oxa101 act as a back-up for oxa102.
Similarity
Belongs to the OXA1/ALB3/YidC family.
Mass
42.06 kDa
Sequence
MLHFLIRPSTRCAGSPHFNSTSSFLRKRLQSKTILSKRLGFQFRPSSTNVLAEVSTATSGFNPSWWPYALIQNTAYTINVYAGAPWWVSIILTTLGVRLALTPVMIASFRNSTKLSVIQPEMKKELEAIKTAKLDNDQLALNQHSIALRGIYLKHNVNPFAIFILPLTQSAVFFSFFYAIRKMSRLSVDGFTTGGLAWFKDLSIPDPYCILPIINAGLMFSGMQMNRANTASTIGNSTNWRTFFFLCCLLSPLLTAKLPAAIFMYWIPSSLFNIVQGYILKNPVVRSKLGFAPLPSIIEKQPSGFTLITNPIKSLKEFYKGVRDGFKTQYEQLQKDVSRRAVATTSASTIRPNSHYKKLKELNRSKKNSKKQSN