otx1a

Homeobox protein OTX1 A

338 amino acids

Plays a role in very early embryogenesis, gastrulation, and the development and subdivision of the diencephalon and the midbrain. Establishes and positions the zona limitans intrathalamica (ZLI) in the diencephalon. May play a role in the organizer function. Probably acts redundantly with otx2 in early brain development.

Belongs to the paired homeobox family. Bicoid subfamily.

36.145 kDa

MMSYLKQAPYAMNGLGLGGATMDLLHPSVGYPTNPRKQRRERTTFTRTQLDILESLFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQSSTNSKIRPAKKKPSPSRESPGSESSGHFTPPAVSSSSSSSSSSSGSNPSALSGVGLISSSSSGTPVPSIWSPAPVSPVPAPPSLPDISPPASASCMQRAMSSGGGTTGVPSYPMPYNQAPSYAQGYPTSNAASYFGGMDCGSYLAPMTGHAHHHPHAHHSQLSTAAAVSGHHHPHHIGQSSGHHPHHQGYGGTALPFSSSDCLDYKEQVASSWKLNFSSAAADCLDYKDQAAWRFQVL