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otub-1

Gene
otub-1
Protein
Ubiquitin thioesterase otubain-like
Organism
Caenorhabditis briggsae
Length
288 amino acids
Function
Hydrolase that can remove conjugated ubiquitin from proteins and plays an important regulatory role at the level of protein turnover by preventing degradation. Specifically cleaves 'Lys-48'-linked polyubiquitin (By similarity).
Similarity
Belongs to the peptidase C65 family.
Mass
32.949 kDa
Sequence
MVNDTSENQPTTAGIVTTTEDELILQDQQMKRIEDEQKASPLVGEKMPCATLVSLYDQETAPAFFEKANELAKVYSHIRFIRGDGNCFIRAIQVGLVEILLNDKERLVKFIASCKEWTERLVKLGFPDWTCTDFCEFFIEFIEKVRDGIHQKEDVFRIFNDDNTANYLLMFFRLITSGYLKEHAAEYEPFLDEGMSLAQYCETEIEAMWKESDHLGIIALVRALNIRIRIEYMDRNAAPNGGTHHNLPDGHDNATFTPDITLLYRPGHYDLIYKAPAETSKPALPPVA

Gene
otub-1
Protein
Ubiquitin thioesterase otubain-like
Organism
Caenorhabditis elegans
Length
284 amino acids
Function
Hydrolase that can remove conjugated ubiquitin from proteins and plays an important regulatory role at the level of protein turnover by preventing degradation. Specifically cleaves 'Lys-48'-linked polyubiquitin.
Similarity
Belongs to the peptidase C65 family.
Mass
32.293 kDa
Sequence
MANEPQKSDDNGQAAEAVVTDDEIVLQDQQLKTIEDEQKSVPLVATLAPFSILCAEYDNETSAAFLSKATELSEVYGEIRYIRGDGNCFYRAILVGLIEIMLKDRARLEKFIASSRDWTRTLVELGFPDWTCTDFCDFFIEFLEKIHSGVHTEEAVYTILNDDGSANYILMFFRLITSAFLKQNSEEYAPFIDEGMTVAQYCEQEIEPMWKDADHLAINSLIKAAGTRVRIEYMDRTAAPNGGWHYDIPSDDQQIAPEITLLYRPGHYDVIYKKDSTEASEIEN