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ost3

Gene
ost3
Protein
Probable dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3
Organism
Dictyostelium discoideum
Length
351 amino acids
Function
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.
Similarity
Belongs to the OST3/OST6 family.
Mass
40.264 kDa
Sequence
MMKSSKVSTILLLLFVVIIGSFCLTYGAPSTTNQKPLTSSEKKLLNDLYDRAKKAGGVVEFKSNLDSKKFVTAQNRPYDLLALFTSSNPKYGCSGCVQLKNQIESFSLSYEPYLNSAGFLEKPIFIVILEVDYNMEVFQTIGLNTIPHLLFIPSGSKPITQKGYAYTGFEQTSSQSISDFIYSHSKIRIEPVKTFYEKYSVQILSFVVFLASVRFLITAYRKRKSPMFWYFLTILLFACVIMGIFYDFIHKPNFYEFDHRQQTYNYFSRGSRSQTVSEGMIMGVSTIAITLIFVFLSDILPNYTNFSSKSKGLLFFMGMSSIIVLLFFQSLAFQIKYYRPLFFIPSVTYHY

Gene
OST3
Protein
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
350 amino acids
Function
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.
Similarity
Belongs to the OST3/OST6 family.
Mass
39.483 kDa
Sequence
MNWLFLVSLVFFCGVSTHPALAMSSNRLLKLANKSPKKIIPLKDSSFENILAPPHENAYIVALFTATAPEIGCSLCLELESEYDTIVASWFDDHPDAKSSNSDTSIFFTKVNLEDPSKTIPKAFQFFQLNNVPRLFIFKPNSPSILDHSVISISTDTGSERMKQIIQAIKQFSQVNDFSLHLPMDWTPIITSTIITFITVLLFKKQSKLMFSIISSRIIWATLSTFFIICMISAYMFNQIRNTQLAGVGPKGEVMYFLPNEFQHQFAIETQVMVLIYGTLAALVVVLVKGIQFLRSHLYPETKKAYFIDAILASFCALFIYVFFAALTTVFTIKSPAYPFPLLRLSAPFK

Gene
OST3
Protein
Probable dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3
Organism
Oryza sativa subsp. japonica
Length
336 amino acids
Function
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.
Similarity
Belongs to the OST3/OST6 family.
Mass
37.591 kDa
Sequence
MESPPHPLLLLLTLLVAAGAASAGADDLVAELQSLRSRSPSGVIHLTDTSITRFLSAPAPRPYSVLVFFDAASLHSKTDLHLPQLRREFALLSASFLAHNPASADLFFADIEFSESQHSFAQFGVNSLPHVRLVRPEHTRLAGSEQMDQSHFSRLADSMAEFVESRTGLEVGPIVRPPLVSRNQMILLVILFLVSIPFLIKRIMDGETLFHDRRVWMAGALFIYFFSVSGGMYGIIRHTPMFITDRSDPNKLVFFYQGSGMQLGAEGFAVGFLYTLVGLMIAMVTHLLVRVESLQIQRFTMLAVMIIGWWAVKKVILLDNWKTGYSIHTFWPSSWR

Gene
ost3
Protein
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Length
309 amino acids
Function
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.
Similarity
Belongs to the OST3/OST6 family.
Mass
34.983 kDa
Sequence
MNFFKILSFFSLFVITCFAKLDLNSKTDADGVIQITGRLFHRIVNGKQDFTTVALFSADSSTMNCDVCRLIEPEFKALANSYKLKYGLDSGIRFTYADFGKNKNLFQDFSIESVPNFWIFKPKSIQAIHVDLSHGVTASHLAAIVEKHTGKIADIVYKQDQAKRVGAFLSYIIVGAALFFTRKIIVKIFTSRKVWAALTIITVITLSSGYMFTRIRFSPYSQRGEHGENLWLAGSQQFQFGAEVQVVSLLYTALTMSSIFLAIVAPKVEGAKRQTLFVIIWLAFLWIGYSFLVDIFKRKVSMYPFKLLI