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ospG

Gene
ospG
Protein
Protein kinase OspG
Organism
Shigella dysenteriae serotype 1 (strain Sd197)
Length
196 amino acids
Function
Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is a kinase that is involved in down-regulation of the host innate response induced by invasive bacteria (By similarity).
Similarity
Belongs to the protein kinase superfamily.
Mass
22.57 kDa
Sequence
MKITSTIIQTPFPFENNNSHAGIVTEPILGKLIGQGSTAEIFEDVNDSSALYKKYDLIGNQYNEILEMAWQESELFNAFYGDEASVVIQYGGDVYLRMLRVPGTPLSDIDTADIPDNIESLYLQLICKLNELSIIHYDLNTGNMLYDKESESLFPIDFRNIYAEYYAATKKDKEIIDRRLQMRTNDFYSLLNRKYL
Protein
Protein kinase OspG: ospG

Gene
ospG
Protein
Protein kinase OspG
Organism
Shigella flexneri serotype X (strain 2002017)
Length
196 amino acids
Function
Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is a kinase that is involved in down-regulation of the host innate response induced by invasive bacteria (By similarity).
Similarity
Belongs to the protein kinase superfamily.
Mass
22.57 kDa
Sequence
MKITSTIIQTPFPFENNNSHAGIVTEPILGKLIGQGSTAEIFEDVNDSSALYKKYDLIGNQYNEILEMAWQESELFNAFYGDEASVVIQYGGDVYLRMLRVPGTPLSDIDTADIPDNIESLYLQLICKLNELSIIHYDLNTGNMLYDKESESLFPIDFRNIYAEYYAATKKDKEIIDRRLQMRTNDFYSLLNRKYL
Protein
Protein kinase OspG: ospG

Gene
ospG
Protein
Protein kinase OspG
Organism
Shigella flexneri
Length
196 amino acids
Function
Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is a kinase that is involved in down-regulation of the host innate response induced by invasive bacteria. Prevents or at least delays host phospho-NF-kappa-B inhibitor alpha (NFKBIA) degradation. Does not phosphorylate E2 enzymes.
Similarity
Belongs to the protein kinase superfamily.
Mass
22.57 kDa
Sequence
MKITSTIIQTPFPFENNNSHAGIVTEPILGKLIGQGSTAEIFEDVNDSSALYKKYDLIGNQYNEILEMAWQESELFNAFYGDEASVVIQYGGDVYLRMLRVPGTPLSDIDTADIPDNIESLYLQLICKLNELSIIHYDLNTGNMLYDKESESLFPIDFRNIYAEYYAATKKDKEIIDRRLQMRTNDFYSLLNRKYL
Protein
Protein kinase OspG: ospG

Gene
ospG
Protein
Protein kinase OspG
Organism
Shigella sonnei (strain Ss046)
Length
196 amino acids
Function
Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is a kinase that is involved in down-regulation of the host innate response induced by invasive bacteria (By similarity).
Similarity
Belongs to the protein kinase superfamily.
Mass
22.57 kDa
Sequence
MKITSTIIQTPFPFENNNSHAGIVTEPILGKLIGQGSTAEIFEDVNDSSALYKKYDLIGNQYNEILEMAWQESELFNAFYGDEASVVIQYGGDVYLRMLRVPGTPLSDIDTADIPDNIESLYLQLICKLNELSIIHYDLNTGNMLYDKESESLFPIDFRNIYAEYYAATKKDKEIIDRRLQMRTNDFYSLLNRKYL
Protein
Protein kinase OspG: ospG