Protein
Intraflagellar transport protein osm-1
Organism
Caenorhabditis elegans
Function
Component of the intraflagellar transport (IFT) complex B required for transport of proteins in the motile cilium (PubMed:28479320). May be required for ciliary entrance and transport of specific ciliary cargo proteins such as che-3 which are related to motility (PubMed:28479320). Required for the maintenance and formation of chemosensory cilia that detect chemosensory cues (PubMed:10545497).
Similarity
Belongs to the IFT172 family.
Sequence
MKLKYLSTILPAQDGEAKISNISCSPNGSRAAIACSDRSVALLDENGVQKDRFTCKPIDAKYGKKSFTVLCMTFSPDSSRIAIGQSDNVLFIYKVGTSWNEKKVIVNKFVQPSAVTCLSWPFDDKILVGQLDGKVRIGLIKTNKCSSLYKTDETVVSIQTHPKRTSFVSAHQDGSIILYNFSSRTQSKICTLQVPPYNLVFTNHGLVVATSDRRVLSYTENGVVQQQFDYNDQSEKEFSSISCDPTAQNVVVASYDRLRLFSWSARRGAWDEGAPLEIQNAYTIGALGWKMDGSTIYAGTVCGGVFSVDCCLRRGMLKSRFETTYVAPSHVILRDVTNDTRTNVISNKGLAIDELKIMGKDRYVIGYTSSSIIIADTESQRFSELEWQSGGHEKFYFDFNNCCLIINAGEVTVVEYGVDGSLGWVRTELTSPHLLSVQVSGPDVEEHKKVKKLAYLVDPTTISIINLINGQQESFINHTGAVDWIELNERASKLLYRDKRSKVTLVDISSDQRSVLLSFCTYVQWVPMSDVIVAQSGDNLSIWYNPDLPEQVTNMKIKGEVEAVLRDADRTEVIVQEPTAKVAYELDNTQIEFGAALEKRDFDRAVAFLESNTSGTDAYSMWIRVAEMALEHGNLFVAQRCYAAINDVAKVRKLHDILEIADEASISIGGDGTHFYKVRAMLAIMGRKFKEAERIFLEQNDTESAIGMYTSLHKWDEALELAKVLNYPEYEQLKTSYLRALSDTGQDSKAAELKVSDGDTLSAIQLYIKSNKPLSALSAANNDSVLSQDENILRQIADSLVKSQLYDKAGDVYEKLKDFDKAVEYFKKGDAYGKAIQLARFAFPEKVVTLEQEWGLHLEYIGQYDAAVNHFVEANDLKKAVEAAIRAKEWPKALSIVENIQDQKVRTGYYGEIADHYSNKGDFERAERLFVEAGLFNDAIMMYGKNNKWIDAFRLSEEFHGREATISSYLAKAEDLDEHGRFAEAEQLYITIGMPHKAIQMYDRVGRDDDVLRLVERYHGEHMHETRKRFATQYEERGDLKAAEEQFLKAGDFRSAVNMYKDSEMWSDAYRIAKTEGGENMEKQVLFMWAKSIGGDAAVKLLNKHGMLMEGIDFACETGAFDLAFDLARIGAKDRMGTVHVRLATQLEEEGRLEDASKHYVEGNKPELAVEMFIRDNDWADAERVAKDHCESLLPDVYTGQARRAIEEGDHLRAETFLLRANKPDIILRYFIENEMWPDALRIAQNYLPHQAALIQEEYEKSELRNGARGVDSFVAQAKEWEQQGDWRKAVSALLKINRDSTDNDALIKHSTEKAADLVMKFLMGDEEYIGAALGALDEANCNEKAAELLLLFGQSRQAINALCRAKQWAKAKQVAQEYLPEMVPEIEKIYKESLKSEGRLGELIDVDVITAIDMMIENDQWDKALDTAKSQNYRPLLDKYVAQYAAILVHRNDLSRVLAVLERYGASANPANFSIYKLLMEETLAKPRFDYTEIARVRNVHLDVYNALQKESSEHFEEFSRALWALHLIAMRTALEEIGDSVPEVQKLCLKQSLSLLRYTDILVADRIFYEAGAAAKDYGSEYESLGFLLLNHYLDLVDAIEEGNGELVDYSPFENSDIPTEVSLPTRQWLESAKHEEMKEWVLASSVDDAHAKELVYDKRGVFEASLKDKRGTAEPCLVTGYPVIESTVRIGSMVAEKDNLNKFLVVIKSNQTENLLNVQNFVAKWAGSPLAISL