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olfml3a

Gene
olfml3a
Protein
Olfactomedin-like protein 3A
Organism
Danio rerio
Length
390 amino acids
Function
Secreted scaffold protein that plays an essential role in dorsoventral patterning during early development. Stabilizes axial formation by restricting chordin (CHRD) activity on the dorsal side. Acts by facilitating the association between the tolloid proteases and their substrate chordin (CHRD), leading to enhance chordin (CHRD) degradation (By similarity).
Similarity
Belongs to the OLFML3 family.
Mass
44.506 kDa
Sequence
MRALQLLVLVLSGLVGAQQQALMDYLERRLLAIEDRISLWHEQTSRYASELREFKQQMVAQLEGLDKSKEALRSELDTVGTRVDRVEREMDYLETQNGAQPCVDVDDKLVEQQVTFVKERNKAKYAKLTDCSDMISSIKAMKILKRVGGAKGMWTKDMGSATGKVYILNGTDDNTVFEFGTVREFTSSQGTSGATTIQLPSAWRGMGHAIYNNHMYYLKQGEEMKLIKFDLQKNIIVDSAVFPVKNQLPVYSLNPETFIDLAVDEEGLWAIYATQENERHISLAKIDPKTLDIQQMWDTPCVRENAEAAFVICGTVYVVYNSKLPSRSRIQCVFDVSDMVNNDEAPHVYFPKRYGTHSSLKYSPVEQLLYAWDDGYQILYKLQLKKKLEV