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oleC

Gene
oleC
Protein
Olefin beta-lactone synthetase
Organism
Shewanella oneidensis (strain MR-1)
Length
614 amino acids
Function
Involved in olefin biosynthesis (PubMed:20418444). Catalyzes the conversion of 2-alkyl-3-hydroxyalkanoic acids to beta-lactones in the presence of ATP (By similarity). The S.oneidensis oleABCD genes produce 3,6,9,12,15,19,22,25,28-hentriacontanonaene, which may aid the cells in adapting to a sudden drop in temperature (PubMed:20418444).
Similarity
Belongs to the ATP-dependent AMP-binding enzyme family.
Mass
66.991 kDa
Sequence
MTKVDDALFEHGASAVAVEQNNGRDNPTKPKDANICRHLKLAAHHIPHHLAVAVQQGKGKSFANLTYQELDFISLNKQSDAIAFALNAYGLTRGMKAVLMVTPSLDFFALTFALFKAGIIPVLVDPGMGIKNLKQCFIEAAPDAFIGIPKAHIARRLLGWGKASVKRLINVDANQSGVTDTLSRLLTGAPSLASMLSFTTKSSSAKLPEQVEYPMALLEHDEMAAILFTSGSTGTPKGVVYSHGMFEAQIQALKQDYGIAHGERDLATFPLFSLFGPALGMTSIVPEMDASKPITANPEFLFAAIEKYQCSNIFVNPALLERLGRAGEQTDSKNQHKLSSVKRVISAGAPATIASIARFSKMLSDGVPVLNSYGATESLPISMIASDELFTTTQVTDNGGGICVGRAIDGVKIEIIAITEADIPEWDNRLCLNAGEIGEIVVTGQMVSQSYYHREKATAASKIWDSERQTFRHRMGDLGYLDDSGRLWMCGRKAHRVDATQGGQFAKRYYSIPCERIFNTHPNVKRSALVGVTVKGQHGVGEIKPLICIELDQSLVCNKSAQLYQELMVIAEQYSQTQGIRRFLIHPDFPVDVRHNAKIFREKLAVWAQSQTKG

Gene
oleC
Protein
Olefin beta-lactone synthetase
Organism
Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)
Length
556 amino acids
Function
Involved in olefin biosynthesis (PubMed:21266575, PubMed:28029240, PubMed:28223313). Catalyzes the conversion of 2-alkyl-3-hydroxyalkanoic acids to beta-lactones in the presence of ATP (PubMed:28029240).
Similarity
Belongs to the ATP-dependent AMP-binding enzyme family.
Mass
59.17 kDa
Sequence
MGDNGRMTTLCNIAASLPRLARERPDQIAIRCPGGRGANGMAAYDVTLSYAELDARSDAIAAGLALHGIGRGVRAVVMVRPSPEFFLLMFALFKAGAVPVLVDPGIDKRALKQCLDEAQPQAFIGIPLAQLARRLLRWAPSATQIVTVGGRYCWGGVTLARVERDGAGAGSQLADTAADDVAAILFTSGSTGVPKGVVYRHRHFVGQIELLRNAFDMQPGGVDLPTFPPFALFDPALGLTSVIPDMDPTRPATADPRKLHDAMTRFGVTQLFGSPALMRVLADYGQPLPNVRLATSAGAPVPPDVVAKIRALLPADAQFWTPYGATECLPVAAIEGRTLDATRTATEAGAGTCVGQVVAPNEVRIIAIDDAAIPEWSGVRVLAAGEVGEITVAGPTTTDTYFNRDAATRNAKIRERCSDGSERVVHRMGDVGYFDAEGRLWFCGRKTHRVETATGPLYTEQVEPIFNVHPQVRRTALVGVGTPGQQQPVLCVELQPGVAASAFAEVETALRAVGAAHPHTAGIARFLRHSGFPVDIRHNAKIGREKLAIWAAQQRV

Gene
oleC
Protein
Olefin beta-lactone synthetase
Organism
Stenotrophomonas maltophilia (strain K279a)
Length
552 amino acids
Function
Involved in olefin biosynthesis (PubMed:27238740, PubMed:28029240). Catalyzes the conversion of beta-hydroxy acid substrates to beta-lactones in the presence of ATP (PubMed:28029240). Can use all four stereoisomers of 2-hexyl-3-hydroxydecanoic acid (PubMed:27238740).
Similarity
Belongs to the ATP-dependent AMP-binding enzyme family.
Mass
58.578 kDa
Sequence
MNRPCNIAARLPELARERPDQIAIRCPGRRGAGNGMAAYDVTLDYRQLDARSDAMAAGLAGYGIGRGVRTVVMVRPSPEFFLLMFALFKLGAVPVLVDPGIDRRALKQCLDEAQPEAFIGIPLAHVARLVLRWAPSAARLVTVGRRLGWGGTTLAALERAGAKGGPMLAATDGEDMAAILFTSGSTGVPKGVVYRHRHFVGQIQLLGSAFGMEAGGVDLPTFPPFALFDPALGLTSVIPDMDPTRPAQADPVRLHDAIQRFGVTQLFGSPALMRVLAKHGRPLPTVTRVTSAGAPVPPDVVATIRSLLPADAQFWTPYGATECLPVAVVEGRELERTRAATEAGAGTCVGSVVAPNEVRIIAIDDAPLADWSQARVLAVGEVGEITVAGPTATDSYFNRPQATAAAKIRETLADGSTRVVHRMGDVGYFDAQGRLWFCGRKTQRVETARGPLYTEQVEPVFNTVAGVARTALVGVGAAGAQVPVLCVELLRGQSDSPALQEALRAHAAARTPEAGLQHFLVHPAFPVDIRHNAKIGREKLAVWASAELEKRA