ogg

Gene

ogg

Protein

Probable N-glycosylase/DNA lyase

Organism

Aquifex aeolicus (strain VF5)

Length

226 amino acids

Function

Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 7-oxoG) from DNA. Also nicks DNA at apurinic/apyrimidinic sites (AP sites) (By similarity).

Similarity

Belongs to the type-2 OGG1 family.

Mass

26.306 kDa

Sequence

MDAIQEVKRIIPEVQKYVNQRMEEFERLGREGWTHFDFRPFLDIDYDAGLFSELSFCILTANSSATLGIKIQAHLGEEGFLNKTKEELEEVFRKFGHRYAGQRAERIVEAREKFPKVKSLIEKEKNSKVIRELLADPKSPYKIKGFGYKEASHFLRNIGFKDLAIIDRHISRFLMEKGLLRQVKSITPKVYLEAEKALESLAKELGLSLGELDLYIFYIKTKKVLK

Protein

Probable N-glycosylase/DNA lyase: ogg

Gene

ogg

Protein

Probable N-glycosylase/DNA lyase

Organism

Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / CIP 101130 / JCM 8532 / LMG 13131)

Length

217 amino acids

Function

Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 7-oxoG) from DNA. Also nicks DNA at apurinic/apyrimidinic sites (AP sites).

Similarity

Belongs to the type-2 OGG1 family.

Mass

25.924 kDa

Sequence

MKKNEYFNEIEKIYKEMSSHFKERLKEFKNIWENGTNKDIHLELSFCILTPQSKALNAWQAITNLKKDDLIYNGKAEELVEFLNIVRFKNNKSKYLVELREKMMKDGEIITKDFFNTLPTVAEKREWIVKNIKGMSYKEASHFLRNVGFGENIAILDRHILRNLVKLEVIDELPKTLTPKLYLEIEEKMRDYCEFVKIPMDEMDLLLWYKEAGVIFK

Protein

Probable N-glycosylase/DNA lyase: ogg

Gene

ogg

Protein

Probable N-glycosylase/DNA lyase

Organism

Korarchaeum cryptofilum (strain OPF8)

Length

209 amino acids

Function

Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 7-oxoG) from DNA. Also nicks DNA at apurinic/apyrimidinic sites (AP sites).

Similarity

Belongs to the type-2 OGG1 family.

Mass

24.48 kDa

Sequence

MGVDDLVNDVMRLKGSRVREIIERRMREFERERSDEELFKELVFCLLTANFSAEGGLRILESLGDGIFTLSEEELAAKLAELGHRYPRKRAEFIVEARKLIPILRDIISSFRDERLLREWLVKNVKGLGYKEASHFLRNIGFKNVSIIDYHILDLLMKYGILEEKPKSLSRARYLMIESILEEISRRTGINLGELDLYLWYIETGKVLK

Protein

Probable N-glycosylase/DNA lyase: ogg

Gene

ogg

Protein

Probable N-glycosylase/DNA lyase

Organism

Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828)

Length

209 amino acids

Function

Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 7-oxoG) from DNA. Also nicks DNA at apurinic/apyrimidinic sites (AP sites).

Similarity

Belongs to the type-2 OGG1 family.

Mass

25.087 kDa

Sequence

MISSDYIKDKILEIENIQGNLIRSRISEFKRLKKSDKYTLFKELSFCILTANTSAELGLKCQAYINDGFYRLDYNDLREELIKVHYRFYNKRASYIIGARDIIDDLEYIVNMDDHFRAREILIERVKGIGYKEASHFLRNVGVFDFAILDKHIIKFMKNNYYIKYENNSSRRRYLENEIVFNELAKKFNMEPGVFDLYIWYIETGKILK

Protein

Probable N-glycosylase/DNA lyase: ogg

Gene

ogg

Protein

N-glycosylase/DNA lyase

Organism

Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

Length

207 amino acids

Function

Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 7-oxoG) from DNA. Also nicks DNA at apurinic/apyrimidinic sites (AP sites). Has little specificity for the base opposite oxoG.

Similarity

Belongs to the type-2 OGG1 family.

Mass

24.827 kDa

Sequence

MMLIKKIEELKNSEIKDIIDKRIQEFKSFKNKSNEEWFKELCFCILTANFTAEGGIRIQKEIGDGFLTLPREELEEKLKNLGHRFYRKRAEYIVLARRFKNIKDIVESFENEKVAREFLVRNIKGIGYKEASHFLRNVGYDDVAIIDRHILRELYENNYIDEIPKTLSRRKYLEIENILRDIGEEVNLKLSELDLYIWYLRTGKVLK

Protein

N-glycosylase/DNA lyase: ogg

Gene

ogg

Protein

Probable N-glycosylase/DNA lyase

Organism

Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)

Length

207 amino acids

Function

Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 7-oxoG) from DNA. Also nicks DNA at apurinic/apyrimidinic sites (AP sites).

Similarity

Belongs to the type-2 OGG1 family.

Mass

24.253 kDa

Sequence

MLRSLVQNPKVRARVLERVDEFRLNNLSNEEVWFRELTLCLLTANSSFISAYQALNCLGQKIYYANEEEIRNILKSCKYRFYNLKAKYIIMAREKVYGRLKEEIKPLADEDQQLARERLLNIKGIGMKEASHFLRNVGYFDLAIIDRHIIDFMRRIGAIGETNVKQLSKSLYISFENILKSIASNLNMSVGILDLFIWYKETNTIVK

Protein

Probable N-glycosylase/DNA lyase: ogg

Gene

ogg

Protein

Probable N-glycosylase/DNA lyase

Organism

Sulfolobus islandicus (strain M.16.27)

Length

207 amino acids

Function

Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 7-oxoG) from DNA. Also nicks DNA at apurinic/apyrimidinic sites (AP sites).

Similarity

Belongs to the type-2 OGG1 family.

Mass

24.071 kDa

Sequence

MLRSLVQNPRVRARVLERVDEFRLNNLSNEEVWFRELTLCLLTANSSFISAYQALNCLGDKIYYANEEVIRSILKSCKYRFYNLKAKYIIMAREKVYGKLKEEITPLADSDQQLAREKLLNIKGIGMKEASHFLRNVGYFDLAIIDRHLIDFMRRIGAIGETNVKHLSKSRYISLESVLKSIALNLNISVGILDLFIWYKETNTIVK

Protein

Probable N-glycosylase/DNA lyase: ogg

Gene

ogg

Protein

Probable N-glycosylase/DNA lyase

Organism

Sulfolobus islandicus (strain M.16.4 / Kamchatka #3)

Length

207 amino acids

Function

Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 7-oxoG) from DNA. Also nicks DNA at apurinic/apyrimidinic sites (AP sites).

Similarity

Belongs to the type-2 OGG1 family.

Mass

24.071 kDa

Sequence

Protein

Probable N-glycosylase/DNA lyase: ogg

Gene

ogg

Protein

Probable N-glycosylase/DNA lyase

Organism

Sulfolobus islandicus (strain L.S.2.15 / Lassen #1)

Length

207 amino acids

Function

Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 7-oxoG) from DNA. Also nicks DNA at apurinic/apyrimidinic sites (AP sites).

Similarity

Belongs to the type-2 OGG1 family.

Mass

24.071 kDa

Sequence

Protein

Probable N-glycosylase/DNA lyase: ogg

Gene

ogg

Protein

Probable N-glycosylase/DNA lyase

Organism

Sulfolobus islandicus (strain M.14.25 / Kamchatka #1)

Length

207 amino acids

Function

Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 7-oxoG) from DNA. Also nicks DNA at apurinic/apyrimidinic sites (AP sites).

Similarity

Belongs to the type-2 OGG1 family.

Mass

24.071 kDa

Sequence

Protein

Probable N-glycosylase/DNA lyase: ogg

Gene

ogg

Protein

Probable N-glycosylase/DNA lyase

Organism

Sulfolobus islandicus (strain Y.N.15.51 / Yellowstone #2)

Length

207 amino acids

Function

Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 7-oxoG) from DNA. Also nicks DNA at apurinic/apyrimidinic sites (AP sites).

Similarity

Belongs to the type-2 OGG1 family.

Mass

24.083 kDa

Sequence

Protein

Probable N-glycosylase/DNA lyase: ogg

Gene

ogg

Protein

Probable N-glycosylase/DNA lyase

Organism

Sulfolobus islandicus (strain Y.G.57.14 / Yellowstone #1)

Length

207 amino acids

Function

Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 7-oxoG) from DNA. Also nicks DNA at apurinic/apyrimidinic sites (AP sites).

Similarity

Belongs to the type-2 OGG1 family.

Mass

24.071 kDa

Sequence

Protein

Probable N-glycosylase/DNA lyase: ogg

Gene

ogg

Protein

Probable N-glycosylase/DNA lyase

Organism

Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

Length

207 amino acids

Function

Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 7-oxoG) from DNA. Also nicks DNA at apurinic/apyrimidinic sites (AP sites) (By similarity).

Similarity

Belongs to the type-2 OGG1 family.

Mass

24.21 kDa

Sequence

MEELLKELERIREEAKPLVEQRFEEFKRLGEEGTEEDLFCELSFCVLTANWSAEGGIRAQKEIGKGFVHLPLEELAEKLREVGHRYPQKRAEFIVENRKLLGKLKNLVKGDPFQSREFLVRNAKGIGWKEASHFLRNTGVEDLAILDKHVLRLMKRHGLIQEIPKGWSKKRYLYVEEILRKVAEAFGESPGKFDLYLWYLVKGKVDK

Protein

Probable N-glycosylase/DNA lyase: ogg

Gene

ogg

Protein

Probable N-glycosylase/DNA lyase

Organism

Thermotoga neapolitana (strain ATCC 49049 / DSM 4359 / NS-E)

Length

207 amino acids

Function

Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 7-oxoG) from DNA. Also nicks DNA at apurinic/apyrimidinic sites (AP sites).

Similarity

Belongs to the type-2 OGG1 family.

Mass

24.21 kDa

Sequence

Protein

Probable N-glycosylase/DNA lyase: ogg

Gene

ogg

Protein

Probable N-glycosylase/DNA lyase

Organism

Thermotoga petrophila (strain RKU-1 / ATCC BAA-488 / DSM 13995)

Length

207 amino acids

Function

Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 7-oxoG) from DNA. Also nicks DNA at apurinic/apyrimidinic sites (AP sites).

Similarity

Belongs to the type-2 OGG1 family.

Mass

24.21 kDa

Sequence

Protein

Probable N-glycosylase/DNA lyase: ogg

Gene

ogg

Protein

Probable N-glycosylase/DNA lyase

Organism

Thermotoga sp. (strain RQ2)

Length

207 amino acids

Function

Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 7-oxoG) from DNA. Also nicks DNA at apurinic/apyrimidinic sites (AP sites).

Similarity

Belongs to the type-2 OGG1 family.

Mass

24.182 kDa

Sequence

MEELLKELERIREEAKPLVEQRFEEFKRLGEEGTEEDLFCELSFCVLTANWSAEGGIRAQKEIGKGFVHLPLEELAEKLREVGHRYPQKRAEFIVENRKLLGKLKNLVKGDPFQSREFLVRNAKGIGWKEASHFLRNTGVEDLAILDKHVLKLMKRHGLIQEIPKGWSKKRYLYVEEILRKVAEAFGESPGKFDLYLWYLVKGKVDK

Protein

Probable N-glycosylase/DNA lyase: ogg

Gene

ogg

Protein

Probable N-glycosylase/DNA lyase

Organism

Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)

Length

204 amino acids

Function

Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 7-oxoG) from DNA. Also nicks DNA at apurinic/apyrimidinic sites (AP sites).

Similarity

Belongs to the type-2 OGG1 family.

Mass

23.886 kDa

Sequence

MLRELVKNKKLRARVLERAEEFKLNNRAEENVWFRELILCILTSNSSFISAYKALNYIMDEIFSLSEDQMSKRLRLAGYRFYNLKAKYIANARKLYGNLKTKIKPIADYSQEEARQYIINNIDGLGLKESSHFLRNVGYFDLAIIDRHVLHFLNEIGTSNLKIKNKKDYYLAESILKSISINLGIQVGLLDLYIFFKQTNTIVK

Protein

Probable N-glycosylase/DNA lyase: ogg

Gene

ogg

Protein

Probable N-glycosylase/DNA lyase

Organism

Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)

Length

204 amino acids

Function

Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 7-oxoG) from DNA. Also nicks DNA at apurinic/apyrimidinic sites (AP sites).

Similarity

Belongs to the type-2 OGG1 family.

Mass

23.69 kDa

Sequence

MDSLISIPFLNDESVRSTIYRKVEEFRSIGKSSKEVLFKELVFCILAANTSASMSLRMQESIGDGFLYLSRDDLRKALKENKYRFYNVRSDFIVKSRNIIDDLPALVASPDHEGSRDYLVENVYGIGYKEASHFLRNVGIFDFAILDKHIMKWMAQYYPVKKNTSRKNYLYNEEIFRNISAGFGIEPGILDLFIWYEETGTVIK

Protein

Probable N-glycosylase/DNA lyase: ogg

Gene

ogg

Protein

Probable N-glycosylase/DNA lyase

Organism

Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1)

Length

204 amino acids

Function

Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 7-oxoG) from DNA. Also nicks DNA at apurinic/apyrimidinic sites (AP sites).

Similarity

Belongs to the type-2 OGG1 family.

Mass

24.267 kDa

Sequence

MDFNQYFLPLFQGEASLIINKKVEEFKLFDRKNKDALFEELCFCILAANTSARMALDMQNRIGKGFLYLSENELREKLKAFKYRFYNVRPRYIVESRDIVDELPYIVSMDNKEEARDLLVENVYGFGYKEASHFLRNVGVFDFAILDKHILEWLSRYFQVKKNTSRKNYLYNESIFREIAKSVGMEPGVLDLYIWYMETGTVIK

Protein

Probable N-glycosylase/DNA lyase: ogg

Gene

ogg

Protein

Probable N-glycosylase/DNA lyase

Organism

Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)

Length

203 amino acids

Function

Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 7-oxoG) from DNA. Also nicks DNA at apurinic/apyrimidinic sites (AP sites).

Similarity

Belongs to the type-2 OGG1 family.

Mass

23.869 kDa

Sequence

MLRSLVLNEKLRARVLERAEEFLLNNKADEEVWFRELVLCILTSNSSFISAYKSMNYILDKILYMDEKEISILLQESGYRFYNLKAKYLYRAKNLYGKVKKTIKEIADKDQMQAREFIATHIYGIGYKEASHFLRNVGYLDLAIIDRHILRFINNLGIPIKLKSKREYLLAESLLRSIANNLNVQVGLLDLFIFFKQTNTIVK

Protein

Probable N-glycosylase/DNA lyase: ogg

Gene

ogg

Protein

Probable N-glycosylase/DNA lyase

Organism

Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)

Length

201 amino acids

Function

Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 7-oxoG) from DNA. Also nicks DNA at apurinic/apyrimidinic sites (AP sites).

Similarity

Belongs to the type-2 OGG1 family.

Mass

23.384 kDa

Sequence

MLRKVVRDARLRARVLERVEEFRLNKRASERVWFRELVLCILTANSSFIGAFTALQYLGDLILYGSIEEISSALKNAGYRFPNLKARYIIESRSYYGKLREIGRVADRDQIEAREILLEIKGLGMKEASHFLRNMGYLDLAIIDRHILRFFSDYLEDQKISSKSKYFELESVFRSIASALDLPVGVLDLYVWYLKTGKLAK

Protein

Probable N-glycosylase/DNA lyase: ogg

Gene

ogg

Protein

Probable N-glycosylase/DNA lyase

Organism

Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)

Length

198 amino acids

Function

Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 7-oxoG) from DNA. Also nicks DNA at apurinic/apyrimidinic sites (AP sites) (By similarity).

Similarity

Belongs to the type-2 OGG1 family.

Mass

22.639 kDa

Sequence

MIEKAISRRIKEFRQLGEKGEVEFDFRPFLDFSVKATIRTELAFCISTANSSATAGLKFQRLLGQGVGVKEALTLAGVRFHNRKAEYIREAFKSFKLVEKALEAESSKAREILLKIKGLGMKEASHFLRNVGREDVAIIDRHILRWLERQGYEVPGTMTAKKYLEVEKILMEISEERGESLAEMDLRIWAEMTGKVLK

Protein

Probable N-glycosylase/DNA lyase: ogg