Protein
NADH-quinone oxidoreductase subunit N 3
Organism
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
Function
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
Similarity
Belongs to the complex I subunit 2 family.
Sequence
MSATAVHSLWTTASGVTSAAPGNSFTAPKIEYTQLMPVLIIVVAAVLGILVEAFVPRRARYHTQLFLTVVAVAGSFAAIVGLAAGGYGTTDAGIVAMGAIAIDGPTLFLQGTILLVAMVALFTFAERRLDPGSNGNRVDSFAAQAGSVPGGEGEKAAVRAGFTTTEVFPLLLFSVAGLLVFPAANDLLTLFIALEVFSLPLYLLCAVARRKRLMSQEAAVKYFLLGAFSSAFLLFGIALLYGYAGSLSYADIANVVDGSVLEIDPALADTMGNDALLLIGGAMILTGLLFKVGAVPFHMWTPDVYQGAPTPVTGFMAAATKVAAFGALLRLLYVALPGLAWDLRPVMWAVAIVTMLGGAIVAITQTDIKRLLAYSSIAHAGFILAGVIAASPEGISSVLFYLLAYSFVTVGAFAVVTLVRDAGGEATHLSKWAGLGRRSPLVAAVFAVFLLAFAGIPLTSGFSGKFAVFKAAAEGGAGALVVVGVLSSAVAAFFYIRVIVLMFFSEPKADGPTVAVPSPLTMTTIAVGVAVTLVLGLAPQYFLDLASQAGVFVR