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nudF-1

Gene
nudF-1
Protein
Nuclear distribution protein nudF 1
Organism
Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Length
467 amino acids
Function
Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs.
Similarity
Belongs to the WD repeat LIS1/nudF family.
Mass
50.764 kDa
Sequence
MSQLLTTRQAEELHKSIIAYLASVNLSESATTLRAELGDAVTIDDATIKKYEGLLEKKWTSVVRLQKKIMDLESRCAALQSELDSATPTSLLRKNQDPTAWLPRAPPRHTLESHRSPVTCVAFHPVFSSLASGSDDTTIKIWDWELGELERTVKGHTKAVLDVDYGGPRGGTLLASCSSDLTIKLWDPSDDYKNIRTLPGHDHSVSSVRFIPSGAAGSPMSGNLLVSASRDKTLRIWDVTTGYCVKTLSGHVDWVRAVAPSIDGRFLFAAGDDRIPRLWDLSAAETRSTFLGHEHVIECVAIAPAASYPHLAVLSGLKKPPSASSSAEFFATGSRDKTIRLWDSRGNLIKTLVGHDNWVRALAFHPGGKYLLSVSDDKTIRCWDLTQECKCVRTIADTHEHFVTCLRWAPPLIKDSGANGDAGANGTPAATTTSNGARQDPNAANKISIRCVIATGSVDQKVRVFAT

Gene
nudF-1
Protein
Nuclear distribution protein nudF 1
Organism
Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Length
467 amino acids
Function
Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs.
Similarity
Belongs to the WD repeat LIS1/nudF family.
Mass
50.764 kDa
Sequence
MSQLLTTRQAEELHKSIIAYLASVNLSESATTLRAELGDAVTIDDATIKKYEGLLEKKWTSVVRLQKKIMDLESRCAALQSELDSATPTSLLRKNQDPTAWLPRAPPRHTLESHRSPVTCVAFHPVFSSLASGSDDTTIKIWDWELGELERTVKGHTKAVLDVDYGGPRGGTLLASCSSDLTIKLWDPSDDYKNIRTLPGHDHSVSSVRFIPSGAAGSPMSGNLLVSASRDKTLRIWDVTTGYCVKTLSGHVDWVRAVAPSIDGRFLFAAGDDRIPRLWDLSAAETRSTFLGHEHVIECVAIAPAASYPHLAVLSGLKKPPSASSSAEFFATGSRDKTIRLWDSRGNLIKTLVGHDNWVRALAFHPGGKYLLSVSDDKTIRCWDLTQECKCVRTIADTHEHFVTCLRWAPPLIKDSGANGDAGANGTPAATTTSNGARQDPNAANKISIRCVIATGSVDQKVRVFAT

Gene
nudF-1
Protein
Nuclear distribution protein nudF 1
Organism
Talaromyces marneffei (strain ATCC 18224 / CBS 334.59 / QM 7333)
Length
459 amino acids
Function
Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs.
Similarity
Belongs to the WD repeat LIS1/nudF family.
Mass
50.783 kDa
Sequence
MSRLLTIRQAEELHKSIIAYLSANNLSNAASALRGELGLSEEVFDTGTMVKYETLLEKKWTSIVRLQKKIMDLEARCGALQTELNNATPTSLSKRNQDPASWLPKVPARYSLESHRNTINCLAFHPKFSSIASGSDDCMIKIWDWELGELETTLKGHTRAVLDVDYGNTQSGVLLASCSSDLSIKIWNPLEDYKNIRTLLGHEHSVSAVRFIPGRNLLTSASRDKDLRIWDVTTGFCVKTIQGHSGWVRDVCPSFDGNYLFSAGDDVTARLWDITNISNPEAKLTMVGHDHVIECCAVAPQTSYQYLAPMAGLKKEALSKMSAVEFTATGSRDKTIKVWDRRGSCLMTLVGHDNWVRAIVFHPGGKYLLSASDDKSIRCWDLSQDGKCVKTLSDAHGRFVTCLRWAPSVVKEVAPSAESANGQTDTNDLLKSKDNQPQVQIRCVVASGGVDQKLNIFAN

Gene
nudF-1
Protein
Nuclear distribution protein nudF 1
Organism
Talaromyces marneffei (strain ATCC 18224 / CBS 334.59 / QM 7333)
Length
459 amino acids
Function
Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs.
Similarity
Belongs to the WD repeat LIS1/nudF family.
Mass
50.783 kDa
Sequence
MSRLLTIRQAEELHKSIIAYLSANNLSNAASALRGELGLSEEVFDTGTMVKYETLLEKKWTSIVRLQKKIMDLEARCGALQTELNNATPTSLSKRNQDPASWLPKVPARYSLESHRNTINCLAFHPKFSSIASGSDDCMIKIWDWELGELETTLKGHTRAVLDVDYGNTQSGVLLASCSSDLSIKIWNPLEDYKNIRTLLGHEHSVSAVRFIPGRNLLTSASRDKDLRIWDVTTGFCVKTIQGHSGWVRDVCPSFDGNYLFSAGDDVTARLWDITNISNPEAKLTMVGHDHVIECCAVAPQTSYQYLAPMAGLKKEALSKMSAVEFTATGSRDKTIKVWDRRGSCLMTLVGHDNWVRAIVFHPGGKYLLSASDDKSIRCWDLSQDGKCVKTLSDAHGRFVTCLRWAPSVVKEVAPSAESANGQTDTNDLLKSKDNQPQVQIRCVVASGGVDQKLNIFAN

Gene
nudF-1
Protein
Nuclear distribution protein nudF 1
Organism
Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255)
Length
458 amino acids
Function
Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs.
Similarity
Belongs to the WD repeat LIS1/nudF family.
Mass
50.144 kDa
Sequence
MSQLLTSRQAEELHKGIIAYLTSVNLHHSSAALREELGDSIRVDDTTLKKYEGLLEKKWTSVVRLQKKIMDLEARCASLQSELDTATPTSLNRKNQDPVSWLPRAPARHDLESHRSPVSCLAFHPIFSSLASGSDDTTIKIWDWELGELERTIKGHTRAVLDVDYGGPRGGTLLASCSSDLTIKLWDPADEYKNIRTLPGHDHSVSAVRFIPSGAAGSPMSGNLLVSASRDLTLRIWDVTTGYCVKSMQGHGDWIRDVTPSPDGRFLFSGGDDRVARLWDISSGDTKSTFLGHEHYIECVAFAPPTSYPHFAALAGLKKPPPASSSAEFVATGSRDKTIRLWDTRGNCIKTLVGHDNWVRSLVFHPGGKYLLSVSDDKTLRCWDLTQECKCVRTIVAHGHFISSLRWAPPLVKDAGANEGANGTEAASNGAKEDATKMSIRCVLATGSVDLKVRVFAA

Gene
nudF-1
Protein
Nuclear distribution protein nudF 1
Organism
Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255)
Length
458 amino acids
Function
Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs.
Similarity
Belongs to the WD repeat LIS1/nudF family.
Mass
50.144 kDa
Sequence
MSQLLTSRQAEELHKGIIAYLTSVNLHHSSAALREELGDSIRVDDTTLKKYEGLLEKKWTSVVRLQKKIMDLEARCASLQSELDTATPTSLNRKNQDPVSWLPRAPARHDLESHRSPVSCLAFHPIFSSLASGSDDTTIKIWDWELGELERTIKGHTRAVLDVDYGGPRGGTLLASCSSDLTIKLWDPADEYKNIRTLPGHDHSVSAVRFIPSGAAGSPMSGNLLVSASRDLTLRIWDVTTGYCVKSMQGHGDWIRDVTPSPDGRFLFSGGDDRVARLWDISSGDTKSTFLGHEHYIECVAFAPPTSYPHFAALAGLKKPPPASSSAEFVATGSRDKTIRLWDTRGNCIKTLVGHDNWVRSLVFHPGGKYLLSVSDDKTLRCWDLTQECKCVRTIVAHGHFISSLRWAPPLVKDAGANEGANGTEAASNGAKEDATKMSIRCVLATGSVDLKVRVFAA