nop-1

Pseudocleavage protein nop-1

759 amino acids

Required for formation of the pseudocleavage furrow during the first cleavage of the embryo and also mediates aster-induced furrowing during cytokinesis. Promotes cortical recruitment of ani-1 and nmy-2 during pseudocleavage and cytokinesis and promotes the accumulation of actin at furrowing regions. Regulates establishment of embryonic cell polarity.

83.663 kDa

MSAPKKRKSDIHSDDRDHADHQTKKEKHWFEEKSEQNGENRRSSIFKGFLKKVKSSTTLKSTNKSASSSKMDTIANETHLSITSESSITSVESCHSAQFPNVAKNAMLRTLVNRDSFTPVPPPDGESVTFILPEIGSSKLEFTSKMDDAISIESRMSIGSCHTIDEDSASIGSTSVFCTPSRNPLMRNGLRMSTRSVPENQDDMPPALFRSLCNSAVRRVPTSKSEGGGTPMRRSMRMSIQKRNLSSKNMEDVPEEEALTVSNSSIRVDAPIAEEDEEVFGAAKEYFDNNVTSHNDSADEGTCSMSRLSTTSERASGVGGSSIFQGRRSSIFRKIFPGKSESKDRRMSDNNQASEQYMDKKSRRASVVSFNEFTSVSGLSVNDSASKNPKDLTESPQQPKLRKKTASSSNLSQRISSVFRMGSNSTVKLNEYVPSPIVSQSSRRNTLTGNSSISSGVGSIASGTSDQGYGTIGSRSGQSISRCGSRRDDEGKKERTRRLLDRIIISDVPAGELLKLKIEQVKKQKQLEMDELFETQLTESSSSDTSQSENLQFDVVAVDIKADGSPFSTTAATFMDSELSKRVKEEIVSNYRPDRCGSITEYEPELVFVMPEQPQASLKSLNDSVSSNADINLDHLRNVRSGLCKSIEEWKRITKMRESSTMLIYPMFCQSEEEWDSKGTIDAIFLMLDGILMNTKRWMPNGKCILAGVTPNNVILLRNKFDELKLSVAISESDGPASSNDDFDTQSTASTSTVFGAKI

nop-1

rRNA 2'-O-methyltransferase fibrillarin

323 amino acids

S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins. Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. Also acts as a protein methyltransferase by mediating methylation of 'Gln-105' of histone H2A (H2AQ105me), a modification that impairs binding of the FACT complex and is specifically present at 35S ribosomal DNA locus (By similarity).

Belongs to the methyltransferase superfamily. Fibrillarin family.

33.812 kDa

MGFERGGRGGARGGGRGGFGGDRGGRGGARGGSRGGFGGGRGGGAPRGRGGPRGGGRGGATRGRGGARGGAKGGAAGKKVIVEPHRHKGVFVARGGKEDLLATVNLVPGESVYGEKRISVENASKEEGGASTKTEYRIWNPFRSKLAAGILGGLETIYMKPGSKVLYLGAASGTSVSHVADIVGPTGSVYAVEFSHRSGRDLINMATRRTNVIPIVEDARKPMAYRMLLPMVDVIFADVAQPDQARIVGINAKLFLKQGGGLLISIKASCIDSTAPPEQVFASEVQKLREDKFFPKEQLTLEPYERDHAMVSCVYQQKEFVDN

nop-1

Opsin-1

304 amino acids

Could facilitate a sensory photoresponse.

Belongs to the archaeal/bacterial/fungal opsin family.

33.487 kDa

MIHPEQVADMLRPTTSTTSSHVPGPVPTVVPTPTEYQTLGETGHRTLWVTFALMVLSSGIFALLSWNVPTSKRLFHVITTLITVVASLSYFAMATGHATTFNCDTAWDHHKHVPDTSHQVCRQVFWGRYVDWALTTPLLLLELCLLAGVDGAHTLMAIVADVIMVLCGLFAALGEGGNTAQKWGWYTIGCFSYLFVIWHVALHGSRTVTAKGRGVSRLFTGLAVFALLLWTAYPIIWGIAGGARRTNVDTEILIYTVLDLLAKPVFGFWLLLSHRAMPETNIDLPGYWSHGLATEGRIRIGEED