Protein
Modification methylase NlaIII
Organism
Neisseria lactamica
Function
This methylase recognizes the double-stranded sequence CATG, causes specific methylation on A-2 on both strands and protects the DNA from cleavage by the NlaIII endonuclease.
Similarity
Belongs to the N(4)/N(6)-methyltransferase family.
Sequence
MNYIGSKLKLSNWLETEISNVAGHSLSDKVFCDLFAGTGIVGRKFKTNVKQVIANDMEYYSYVLNRNYIGNCQSILKAGELLQRLEQLPPREGLIYQHYCLGSGSERQYFSDENGKKIDAVRIQIEEWKNTRYIDEDTYYFLLATLLEGADKVANTASVYGAFLKNLKKSALKPLSLEPALFEIGSDGHQVYQADANQLIKNISGDILYLDPPYNARQYGANYHLLNSIALYDDFTPKGKTGLREYSRSKYCSKSDVVPVFEALIRDADFQYIFLSYNNEGLMSVGQVREIFERFGKYDLVQTEYRRFKADKTENRNHKANSTFEYLHILEKTF