Protein
Nipped-B-like protein A
Function
May play a structural role in chromatin. Involved in sister chromatid cohesion, possibly by facilitating the cohesin complex loading. Transcription factor, which may promote cortical neuron migration during brain development by regulating the transcription of crucial genes in this process (By similarity).
Similarity
Belongs to the SCC2/Nipped-B family.
Sequence
MNGDMPHVPITTLAGIAGLTDLLNQLPLPSPLPGTTTKSLLYNGRVAEDVGHLLGCRDETLVSQLANSLSQVSTEHIELKDSLGSDELEGDVPVLLQLLMSRNPNIFRNKTAPNTPQYPAQAGISQQSMAPPYKITHGSMQGSPASANYQQASMSHSPSGHFVPGQSGPGGRFLPQQGSPVPSPYAPQSPATGYRQYPHPPAYSQHQHLQQGSVASPMIPGAMRNVHENKDQMRMGFTSHLLQSSPPYTPPCDGTKDLHLGSQDKQRGQKSSEGEQDSPDKATVYDIVGSPAKDHTKLILRPSRARPAEVELGGMYPGSDPEGELVEALAAIERMESEAAMETERSAKEVQDKDKPLKKRKQDSHPQEPGAAGTAGSGSGAPGGGGGANAGHRLAPQEASAAGTSASRPGLQVSLEQAGRVEDDCMGMPIPASEAQRWPQEPQEGVTPKAVKHEHDHDPEHPHYDDKQPDTPRQKHRPEGRHGDGGAQRAAVQSGSKQVELPPYMLGENTGVLKNFTIPKIRKGELGGGDIPEGWKQPCVRLERLEADVDVKKSVKPVVVLQKLSIDEVQRLMRERDSRASKSGKNRLSSGRSGKGGIDPSVLKDLPPELLAEIESTMPLCERVKMNKRKRSTVNERPKYAEDSSEDEEFSSRKRQRKDRDRTWEAEERDRRSSGEHRRGNFDARRGSGSRYDDSDQDSPPPSLNEVARRLKMKQKKRKVYEPKLTPEEMMDSSTFKRFTLSIDNILENLEDVDFTAQDDDEIPQELLLGKQQLNELGSESAKIKAMGITSRIPSDKLVKLLNILEKNILDGASLSTLMNLDNEGEDEERLWRDLIMERVTKSADACLTALNIMTSTHMPKAVYIEDVIERVLQYTKFHLQNTLYPQYDPVYRVNPKGGSMLSSRAKRAKCSTAKQKVIIMLYNKVCDVVSNISELLEIQLMTDTTILQVSSMGITPFFVENVSELQLCAIKLVTAVFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDDEGEPIYIQMVSALVLQLIQCVVHLPADRDSEDDHKKVDDDVFITNSYETARRTAQNFLSVFLKKCGSKQGEEDYRPLFENFVQDLLSTVNKPDWPASELLLSLLGRLLVHQFSNKQTEMALRVASLDYLGTVAARLRKDSVTSRMDQKAIERIIRENTEGDETQRLQKALLDYMDENAETDPALAFARKFYIAQWFRDCTTETEKAMRSQNQKEDDSDGAQHAKELQATGDIMQRAETRKKFLHSVVKSTPNQFTTLRMNSDTVDYDDACLIVRYLASTRPFSQSFDIYLTQILRVLGESAIAVRTKAMKCLSEVVAVDPSILARSDMQRGVHGRLMDNSTSVREAAVELLGRFVLSRPQLTEQYYDMLIERILDTGISVRKRVIKILRDICLEQPNFSKITEMCVKMIRRVNDEEGIKKLVNETFQKLWFTPTPNHDKETMNRKILNITDVVSACKDTGYDWFEQLLQNLLKSEEDSSYKPTRKACVQLVDNLVEHILKYEEALAEHKSVNSTRLVACITTLYLFSKIRAQLMVKHAMTMQPYLTTKCSSQSDFMVICNVAKILELVVPLMDHPSESFLTTIEEDLMKLILKYGMTVVQYCVSCLGAIVNKVTHNYKFVWACFNRYYGALTKLKVQHQEGTNSMALAATKAALLRSLFTAGALCRHFDFDLEQFKGTTKVVIKEKVLELLLYFTNHEDEEVKCKAIIGLGFLFIMHPSQMFVPEVKTLYNGLLSDKRSSITLKIQVLKNLQMYLQEEDTRMQEADREWQKLSKQEDLKEMGDISSGMSSSIMQLYLKQVLESFFHAQSSVRHFALNVIALTLSQGLIHPVQCVPYLIAMGTDAEPTMRNKADQQLVEIDKKYTGFIHMKAVAGMKMSYQVQQAVFGSAGSVIRGFRQDESNSAQCSHLYSMVRANRQHRRAFLISLLNLFDDSSKMEVNMLLFIADNLAYFPYQSQEEPLFIMHHIDITLSVSGSNLLQTFKESLVKIPGRKSRKRRRRRRRPQRQQPPPPPPQQQQQQNGSEEERGAQDEERERHSGDEEYDDDDYEEDEDGHRVRKPKPTEDIRQSESDSDSDLDDVDAVMERLPDDSTSLVDFARASQGILLLLVLKQHLKNLYGFSDGKIQKYSPSESAKVYDKAVNRKTLANFNPQQTIDFLRHHDVHGELTYELKRKIVKQFLDFKLLMEHLDPDEEDEDGDTSANVRNKAITALLGGAAASPRNHHTGDSEEDDERSEGEERTPGASRRGRRTGDSADLLSANMNESVSALDIIAIHCPKYRDRPQIARVIQKNSDGYSIHWMAGSYSSTWAEAKKRDGRKLVPWVDSIKETDIIYKKITLTSGNKLNHKVAQTLRSLYAAKDRNSS