Protein
2,5-dihydroxypyridine 5,6-dioxygenase
Organism
Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)
Function
Catalyzes the dioxygenolytic ring cleavage of 2,5-dihydroxypyridine between carbons 5 and 6 generating N-formylmaleamate in the aerobic nicotinate degradation pathway.
Sequence
MPVSNAQLTQMFEHVLKLSRVDETQSVAVLKSHYSDPRTVNAAMEAAQRLKAKVYAVELPAFNHPTAMGNDMTAYCGDTALTGNLAAQRALEAADLVVDTMMLLHSPEQEQILKTGTRILLAVEPPEVLARMLPTEDDKRRVLAAETLLKQARSLHVRSKAGSDFHAPLGQYPAVTEYGYADEPGRWDHWPSGFLFTWPNEDSAEGTLVLDVGDIILPFKNYCRERITLEIEKGFITGIHGGFEAEYLRDYMKYFNDPEVYGISHIGWGLQPRAQWTAMGLHDRNDGMCMDARAFYGNFLFSTGPNTEVGGKRKTPCHLDIPLRNCDIYLDDKAVVLAGDVVAPEESRAR