Protein
HTH-type transcriptional repressor NicR
Organism
Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)
Function
Transcriptional repressor for the nicCDEFTP and nicXR operons, encoding the lower aerobic nicotinate degradation pathway. Acts under non-induced conditions: repression of the nicCDEFTP and nicXR operons becomes alleviated in presence of 6-hydroxynicotinate (6HNA).
Sequence
MSKKTTPSSAPLDNTPYDVTEQVGHLLRKAYQRHTAIFQQQACDPQLTSIQFVTLCALRDHGPSSQAELIKATAVDQATIRGIVERLKARELVQLSPDPGDRRKVIVELTESGAALLDAMIPCARQISELSMGSLNAGERVAILYLLRKMIDSDENAG