Protein
NADH-dependent flavin reductase subunit 2
Organism
Lactobacillus johnsonii (strain CNCM I-12250 / La1 / NCC 533)
Function
Component of an enzyme that catalyzes the reduction of free flavins (FMN, FAD and riboflavin) by NADH; the reduced flavins produced by this reaction likely spontaneously react with oxygen, yielding hydrogen peroxide. Is responsible for the major H(2)O(2) production in L.johnsonii in the presence of oxygen. Cannot use NADPH instead of NADH as the electron donor.
Similarity
Belongs to the NADH-dependent flavin reductase family.
Sequence
MKLLAIVGTNADFSYNRFLDQFMAKRYKDQAEIEVYEIADLPRFKKEAQPDSKVEEFKNKIREADGVIFATPEYDHGIPSALKSAMEWTGSHAQGNADVMKMKPAMVLGTSYGIQGASRAQEEMREILLSPDQSANVLPGNEVLIGHAADKFDKNTGDLLDQETIHAIDLAFNNFVKFVEQAQK