Protein
Negative regulator of transcription
Organism
Escherichia phage D108
Function
Switches off the PcM promoter thereby blocking expression of the major repressor Repc (latency factor) and favoring transcription from the early promoter (Pe) and hence viral transposition and lytic development. Negatively regulates the early promoter (Pe) thereby controlling its own expression and keeping the level of early genes expression independent of the viral genome copy number (By similarity).
Similarity
Belongs to the ner transcriptional regulatory family.
Sequence
MHMNKRTNRQDWHRADIVAELRKRNMSLAELGRSNHLSSSTLKNALDKRYPKAEKIIADALGMTPQDIWPSRY