neoA

Gene

neoA

Protein

2-deoxy-scyllo-inosamine dehydrogenase

Organism

Streptomyces fradiae

Length

340 amino acids

Function

Catalyzes the oxidation of 2-deoxy-scyllo-inosamine (DOIA) with NAD(+) or NADP(+), forming 3-amino-2,3-dideoxy-scyllo-inosose (amino-DOI).

Similarity

Belongs to the zinc-containing alcohol dehydrogenase family. DOIA dehydrogenase subfamily.

Mass

35.228 kDa

Sequence

MKALVFEAPERAVLTHRDIPAPAPGEALVRVAYNSVCGSDLSFYKGVWHGFTYPVVPGHEWSGSVVDVNGPRGADLVGRNVVGDLTCSCGTCAHCAAGTPTLCEDLGELGFTRDGACAEYMTVPVANLRPLPDTLPLRTACQVEPLAVALNAVDRLGVTPGEKVAVMGAGGIGLLLVQAVRLRGGTVTAVAEPVPERRAAALALGVPAAVGGDPGALVELTRSDPAAVPDVVLEASGYPTAVQEAVEAVRPGGRVGLVGYRIEEAAVMAPHHIVLKVLTVRASMGPGTRFEEAVDVLASGAVDVDALLSHEFALDDYAKALDVALRRADGNTRSYFNLRA

Protein

2-deoxy-scyllo-inosamine dehydrogenase: neoA