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nac

Gene
nac
Protein
GDP-fucose transporter 1
Organism
Drosophila melanogaster
Length
337 amino acids
Function
Involved in GDP-fucose import from the cytoplasm into the Golgi lumen. Plays a major role in the fucosylation of N-glycans. Functions redundantly with Efr in the O-fucosylation of Notch, positively regulating Notch signaling.
Similarity
Belongs to the TPT transporter family. SLC35C subfamily.
Mass
38.107 kDa
Sequence
MYKNLEEHNRLVNKYLKIFFVVSLYWCTSILTVFVNKHLLSSDTVNLGAPLFMSWFQCVVSTVICFVASRLSRKYPSVFTFPEGNPLDIDTFRKILPLSVLYTLMIGANNLSLSYVTVAFYYIGRSLTTVFSVVLTYVILRQRTSFKCLLCCGAIVVGFWLGVDQESLTEVFSWRGTIFGVLSSLALAMFSIQTKKSLGYVNQEVWLLSYYNNLYSTLLFLPLIIINGELESIITYPHLWASWFWAAMTLSGLCGFAIGFVTALEIKVTSALTHNISGTAKACAQTVIATQYYHDVRSALWWTSNVVVLVASAAYTRVKQLEMMRQHQQRSTATQKA

Gene
nac
Protein
GDP-fucose transporter 1
Organism
Drosophila melanogaster
Length
337 amino acids
Function
Involved in GDP-fucose import from the cytoplasm into the Golgi lumen. Plays a major role in the fucosylation of N-glycans. Functions redundantly with Efr in the O-fucosylation of Notch, positively regulating Notch signaling.
Similarity
Belongs to the TPT transporter family. SLC35C subfamily.
Mass
38.107 kDa
Sequence
MYKNLEEHNRLVNKYLKIFFVVSLYWCTSILTVFVNKHLLSSDTVNLGAPLFMSWFQCVVSTVICFVASRLSRKYPSVFTFPEGNPLDIDTFRKILPLSVLYTLMIGANNLSLSYVTVAFYYIGRSLTTVFSVVLTYVILRQRTSFKCLLCCGAIVVGFWLGVDQESLTEVFSWRGTIFGVLSSLALAMFSIQTKKSLGYVNQEVWLLSYYNNLYSTLLFLPLIIINGELESIITYPHLWASWFWAAMTLSGLCGFAIGFVTALEIKVTSALTHNISGTAKACAQTVIATQYYHDVRSALWWTSNVVVLVASAAYTRVKQLEMMRQHQQRSTATQKA

Gene
nac
Protein
Nitrogen assimilation regulatory protein nac
Organism
Klebsiella aerogenes
Length
305 amino acids
Function
Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation. Negative regulator of its own expression.
Similarity
Belongs to the LysR transcriptional regulatory family.
Mass
32.754 kDa
Sequence
MNLRRLKYFVKIVDIGSLTQAAEVLHIAQPALSQQVATLEGEMDQQLLIRTKRGVTPTEAGKILYTHARTILRQCEQAQLAVNNVGQTLRGQVSIGLAPGTAASAITMPLLQTVRNELPEVMVYLQESSGTALNDKLLAGQLDMAVLYERSPVAGIVSQPLLKEDLYLVGTRDCPGQSVDLTAVAEMNLFLPRDYSAVRARVTEAFTLRRLSAKIIGEIESITTLTAAIASGMGATVLPESAARSLCGAANGWMARISTPSMSLSLSLNMSARGSLSPQAQAVKEILLSLVSRPSLENRELQLVS

Gene
nac
Protein
Nitrogen assimilation regulatory protein nac
Organism
Escherichia coli (strain K12)
Length
305 amino acids
Function
Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation. Negative regulator of its own expression (By similarity).
Similarity
Belongs to the LysR transcriptional regulatory family.
Mass
32.835 kDa
Sequence
MNFRRLKYFVKIVDIGSLTQAAEVLHIAQPALSQQVATLEGELNQQLLIRTKRGVTPTDAGKILYTHARAILRQCEQAQLAVHNVGQALSGQVSIGFAPGTAASSITMPLLQAVRAEFPEIVIYLHENSGAVLNEKLINHQLDMAVIYEHSPVAGVSSQALLKEDLFLVGTQDCPGQSVDVNAIAQMNLFLPSDYSAIRLRVDEAFSLRRLTAKVIGEIESIATLTAAIASGMGVAVLPESAARSLCGAVNGWMSRITTPSMSLSLSLNLPARANLSPQAQAVKELLMSVISSPVMEKRQWQLVS

Gene
nac
Protein
Nascent polypeptide-associated complex protein
Organism
Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)
Length
130 amino acids
Function
Contacts the emerging nascent chain on the ribosome.
Similarity
Belongs to the NAC-alpha family.
Mass
13.908 kDa
Sequence
MFGGGGGMNPRKMKQMMEQMGIDMEDIDAQEVIIRTPDEELVFDDAEVQLMEAQGQKTYQVVGEPESRELGSGEGSAAAEGDSDESDSSSGVDEDDVELVAMRAGVDEDTAREALEANDGDLADAVDELE

Gene
nac
Protein
Nascent polypeptide-associated complex protein
Organism
Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
Length
130 amino acids
Function
Contacts the emerging nascent chain on the ribosome.
Similarity
Belongs to the NAC-alpha family.
Mass
13.87 kDa
Sequence
MFGGGGMNPRKMQQMMEQMGIDVDELDATEVVISLDDGTEVVFSDPDVTKMDARGQETYQVLGDPVERDAADAIEAAPADDSDDTDDDDAIPQGDVDIVVQRASVPEDEAREALEAADGDLAAAIDHVDE

Gene
nac
Protein
Nascent polypeptide-associated complex protein
Organism
Methanococcus aeolicus (strain ATCC BAA-1280 / DSM 17508 / OCM 812 / Nankai-3)
Length
130 amino acids
Function
Contacts the emerging nascent chain on the ribosome.
Similarity
Belongs to the NAC-alpha family.
Mass
15.051 kDa
Sequence
MFPGRMNPKMMRQMQKMMSDMGMDSKDIKVLKITMELEDKIMVFEKPKVQVMDVMGNKTYTITGRAKNIKKDDIKAEQKEQIKDEEVKLDITKEDIEMVVNQCEVSEEEAKKVLEECNGDIAEAILKLSQ

Gene
nac
Protein
Nascent polypeptide-associated complex protein
Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
Length
128 amino acids
Function
Contacts the emerging nascent chain on the ribosome.
Similarity
Belongs to the NAC-alpha family.
Mass
14.958 kDa
Sequence
MFPGKVNPRMLKKMQKMMKDFGMETEDLDVRKVIFVFDDEEWVFEEPKVQVMDILGVKTYSITGKPKKIKKEKVEEEEEVKVEITEEDVELVAKQCNVSKEEARKALEECNGDIAEAILKLEEEKEEN

Gene
nac
Protein
Nascent polypeptide-associated complex protein
Organism
Methanococcus maripaludis (strain C5 / ATCC BAA-1333)
Length
126 amino acids
Function
Contacts the emerging nascent chain on the ribosome.
Similarity
Belongs to the NAC-alpha family.
Mass
14.004 kDa
Sequence
MFPGGGKFNPRMMKQMQKMMKDFGMDAEDLKAVKVTIELEDTILVFEKPKVQVMDMLGNKTYSITGKAKKVAKAEEKIEDVEVKVEVTEEDIEMVSSQCGVSKEEAKKALEEANGDLAEAILKLGN

Gene
nac
Protein
Nascent polypeptide-associated complex protein
Organism
Methanococcus maripaludis (strain C6 / ATCC BAA-1332)
Length
126 amino acids
Function
Contacts the emerging nascent chain on the ribosome.
Similarity
Belongs to the NAC-alpha family.
Mass
13.99 kDa
Sequence
MFPGGGKFNPRMMKQMQKMMKDFGMDAEDLKAVKVTIELEDTILVFEKPKVQVMDMLGNKTYSITGKAKKVAKAEEKIEDVEVKVEVTEEDVEMVSSQCGVSKEEAKKALEEANGDLAEAILKLGN

Gene
nac
Protein
Nascent polypeptide-associated complex protein
Organism
Methanococcus maripaludis (strain C7 / ATCC BAA-1331)
Length
126 amino acids
Function
Contacts the emerging nascent chain on the ribosome.
Similarity
Belongs to the NAC-alpha family.
Mass
14.089 kDa
Sequence
MFPGGGKFNPRMMKQMQKMMKDFGMDAEDLKAVKVTIELEDQLLVFEKPKVQVMDMLGNKTYSITGKAKKVAKEEEKIEDVEVKVEVTEEDIEMVSSQCGVSKEEAKKALEEANGDLAEAILKLGN

Gene
nac
Protein
Nascent polypeptide-associated complex protein
Organism
Methanococcus maripaludis (strain S2 / LL)
Length
126 amino acids
Function
Contacts the emerging nascent chain on the ribosome.
Similarity
Belongs to the NAC-alpha family.
Mass
14.13 kDa
Sequence
MFPGGGKFNPRMMKQMQKMMKDFGMDAEDLKAVKVTIELEDKLLVFEKPKVQVMDMLGNKTYSITGKAKKVAKEEEKIEDVEVKVEVTEEDIDMVSNQCGVSKEEAKKALEEVNGDLAEAILKLGN

Gene
nac
Protein
Nascent polypeptide-associated complex protein
Organism
Methanococcus vannielii (strain ATCC 35089 / DSM 1224 / JCM 13029 / OCM 148 / SB)
Length
125 amino acids
Function
Contacts the emerging nascent chain on the ribosome.
Similarity
Belongs to the NAC-alpha family.
Mass
14.047 kDa
Sequence
MFPGGKMNPRMMKQMQKMMKDFGMDSEDLKAVKVTIELEDKIMVFDKPKVQVMDMMGTKTYTISGRSKNTSKTAEKIEDTEVKVEVTEEDIEMVATQCNVSKEEAKTALEDVNGDLAEAILKLGN

Gene
nac
Protein
Nascent polypeptide-associated complex protein
Organism
Natronomonas pharaonis (strain ATCC 35678 / DSM 2160 / CIP 103997 / NBRC 14720 / NCIMB 2260 / Gabara)
Length
124 amino acids
Function
Contacts the emerging nascent chain on the ribosome.
Similarity
Belongs to the NAC-alpha family.
Mass
13.448 kDa
Sequence
MFGGGGGLNPRKMKQMMNQMGIDLEEIDAEEVVIRTADEELVFDDAEVQLMDAQGQQTYQVVGEPESRERGDSGSEDDSETESGGEFSEDDVEIVAQRAGVSESTARETLEETGDLAAAVQKLE

Gene
nac
Protein
Nascent polypeptide-associated complex protein
Organism
Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)
Length
120 amino acids
Function
Contacts the emerging nascent chain on the ribosome.
Similarity
Belongs to the NAC-alpha family.
Mass
12.839 kDa
Sequence
MFPGMGGVGGRGMNPAKMKQMMKQMGIDVKELKDVEEVVIKTADSNIVIENANVTIMTVQGSETYQIVGDVKEVPKSLEIPAEDIKLVMEQTGVSEEEARNALKNSNGDLAEAIVALSSA

Gene
nac
Protein
Nascent polypeptide-associated complex protein
Organism
Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
Length
119 amino acids
Function
Contacts the emerging nascent chain on the ribosome.
Similarity
Belongs to the NAC-alpha family.
Mass
13.41 kDa
Sequence
MIPGRMNSREMRRLMAQMGIKSTEMDDVTKVIFKGKTKDYVIDNAQVTMIEAQGVKTFQVVGTMREVPKEPEEKKEESFPEDDIKLVMEQASVSREKAIEALKASGGEPAQAIMNLMQK

Gene
nac
Protein
Nascent polypeptide-associated complex protein
Organism
Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1)
Length
119 amino acids
Function
Contacts the emerging nascent chain on the ribosome.
Similarity
Belongs to the NAC-alpha family.
Mass
13.39 kDa
Sequence
MIPGRMNSREMRRLMAQMGIKSTEMDDVKKVIFVGKEKDYVIENAQVTMIEAQGVKTFQVVGDFRETPKKQEGKKEETFPEDDIKLVMDQTGVAREKAIEALKAASGEPAQAILNLTQK

Gene
nac
Protein
Nascent polypeptide-associated complex protein
Organism
Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)
Length
117 amino acids
Function
Contacts the emerging nascent chain on the ribosome.
Similarity
Belongs to the NAC-alpha family.
Mass
13.286 kDa
Sequence
MIPGMGMNPKQLKQMQRAMKQMGMDMKDLRGVEEVVIKLKRKEIIIKNPKVNVMEFMGQKTYQVTGKARERSLEAEMEIPEDDIELVMNQTGASREDATRALQETGGDLAEAIMRLS

Gene
nac
Protein
Nascent polypeptide-associated complex protein
Organism
Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 / Marburg)
Length
117 amino acids
Function
Contacts the emerging nascent chain on the ribosome.
Similarity
Belongs to the NAC-alpha family.
Mass
13.242 kDa
Sequence
MIPGMGMNPKQLKQMQRAMKQMGMDMKDLRGVEEVVIKLKKKEIIIKNPRVNVMDFMGQKTYQVTGKARECDLEAEVKIPDDDIELVMNQTGVSREEATRALQETGGDLAEAIMRLS

Gene
nac
Protein
Nascent polypeptide-associated complex protein
Organism
Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
Length
117 amino acids
Function
Contacts the emerging nascent chain on the ribosome.
Similarity
Belongs to the NAC-alpha family.
Mass
12.873 kDa
Sequence
MLPVNPRDLEKMMRRLGIKVEQLSADEARIVLGSGETMVFRSPTVIVMRAKGQPPMVYLVGDYTVEKPREETAAEITEEDVALVAEQAGVSMEEARKALEESGGDIAEAILRLKGEE

Gene
nac
Protein
Nascent polypeptide-associated complex protein
Organism
Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)
Length
116 amino acids
Function
Contacts the emerging nascent chain on the ribosome.
Similarity
Belongs to the NAC-alpha family.
Mass
13.216 kDa
Sequence
MFPGGKIDPRKLQRLMREMGMEQEPISGVERVEIHLKDGSKLVFEKPQVIRMKIMNQEFYQVAGKAKREKPEEEPFTDEDVKLVAEQAGVSEEEARKALEETGGDLAEAIMRLQGE

Gene
nac
Protein
Nascent polypeptide-associated complex protein
Organism
Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)
Length
116 amino acids
Function
Contacts the emerging nascent chain on the ribosome.
Similarity
Belongs to the NAC-alpha family.
Mass
13.088 kDa
Sequence
MPKFNPKQMKDLERMLGLKTEQLNAVKVTIELQDKILVIDNPVVVKMLAQGQEVFSVMGSAREESKQQQKVEIKEEDVKFIMEQTGKSEKEAREALEKSNGDIAKAILALTEGENK

Gene
nac
Protein
Nascent polypeptide-associated complex protein
Organism
Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Length
115 amino acids
Function
Contacts the emerging nascent chain on the ribosome.
Similarity
Belongs to the NAC-alpha family.
Mass
12.995 kDa
Sequence
MRKMMPMNPKQLKKLMKQLDMRQLEGVKEVIIKMEDREIIIKEPIVTVIKAMGEKMYQIAGGSEEEKAIINISEEDIKLVMEQAGVDYETAKKALEETGGDLAEAILRLTDSGVE

Gene
nac
Protein
Nascent polypeptide-associated complex protein
Organism
Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)
Length
114 amino acids
Function
Contacts the emerging nascent chain on the ribosome.
Similarity
Belongs to the NAC-alpha family.
Mass
12.779 kDa
Sequence
MKPKPSQFKNLERMLGLKTEQLDAVKVTIELKDKILIIENPTVIKMIAQGQEIYSVIGEAKEAQKEEPKVEIKDEDVKFVMEQTGKGEQEVKEALQKANGDIAKAILLLTGQET

Gene
nac
Protein
Nascent polypeptide-associated complex protein
Organism
Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)
Length
113 amino acids
Function
Contacts the emerging nascent chain on the ribosome.
Similarity
Belongs to the NAC-alpha family.
Mass
12.164 kDa
Sequence
MGGRGMNPAKMKQMMKQMGIDVKELKDVKEVIIKTADSNIVIENANVTIMTVQGSETYQIVGDAKEVPKSLEIPADDIKLVMEQTGVSEEEARNALKNSNGDLAEAIVALSSA

Gene
nac
Protein
Nascent polypeptide-associated complex protein
Organism
Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Length
111 amino acids
Function
Contacts the emerging nascent chain on the ribosome.
Similarity
Belongs to the NAC-alpha family.
Mass
12.541 kDa
Sequence
MMPMNPKQLKKLMKQLDMRQLDNVVEVIIRLEDREIIIKNPTVTVIKAMGEKIYQIAGGEEEEKVKLVISEEDIKLVMEQTGVDYETAKKALEEANGDLAEAILKLTEGSP

Gene
nac
Protein
Nascent polypeptide-associated complex protein
Organism
Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
Length
111 amino acids
Function
Contacts the emerging nascent chain on the ribosome.
Similarity
Belongs to the NAC-alpha family.
Mass
12.436 kDa
Sequence
MMGMNPRQMKKLMKQLGIKMEELEGVEEVVLRMKGKEIILKEPAVTVMVVQGEKTYQIIPGSEEVREVLEISEDDIKLVMEQAGVDYDTAKKALEEAKGDLAEAILKLTEG

Gene
nac
Protein
Nascent polypeptide-associated complex protein
Organism
Pyrococcus abyssi (strain GE5 / Orsay)
Length
109 amino acids
Function
Contacts the emerging nascent chain on the ribosome.
Similarity
Belongs to the NAC-alpha family.
Mass
12.287 kDa
Sequence
MMPMNPKQLKKLMKQLDMKQLDGVKEVIIKLENKEIVIKEPVVTVIRAMGEKMYQIAGGTEEERVVLKISEEDIKLVMEQAGVDYETAKKALEEAGGDLAEAILRLTDQ

Gene
nac
Protein
Nascent polypeptide-associated complex protein
Organism
Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Length
109 amino acids
Function
Contacts the emerging nascent chain on the ribosome.
Similarity
Belongs to the NAC-alpha family.
Mass
12.467 kDa
Sequence
MLPMNPKQMKKMMKQMGIEMEELDAEEVIIRTSDEELIFRNPNVSKISARGVETFQIVGEYEVVKRPPKISEDDIKLIMEQANVDEETARRALEEAGGDLAEALMKLQE

Gene
nac
Protein
Nascent polypeptide-associated complex protein
Organism
Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828)
Length
108 amino acids
Function
Contacts the emerging nascent chain on the ribosome.
Similarity
Belongs to the NAC-alpha family.
Mass
12.204 kDa
Sequence
MNPREIRRMMAQMGIKSTEMSDVKQVIFKGKDKDYIIDNASVTMIEAQGQKTFQVLGNLREVKKEVEQYSEDDIKLVMEQAKVTREKAIEALKAANGEPAQAILNLTS