Protein
Unconventional myosin-Ic-A
Function
Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (By similarity). Involved in egg activation by coupling dynamic actin to membrane.
Similarity
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
Sequence
MENALTARDRVGVQDFVLLENYTSEAAFIENLRKRFKENLIYTYIGSVLVSVNPYKDLEIYSKQHMERYRGVSFYEVSPHIYAIADNSYRSLRTERKDQCILISGESGSGKTEASKKILQYYAVTCPASDQVETVKDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDYKGAPVGGHILNYLLEKSRVVHQNHGERNFHIFYQLLEGGEEELLRRLGLDKNAQNYQYLVKGQCARVSSINDKSDWKTVRRALSIINFNEEDIEELLSIVASVLHLGNVQFASDDHSHAQVTTENQIKYIARLLAVDATAFRESLIHKKIIAKGEELNSPLNLEQAAYARDAFAKAIYGRTFSWLVRNINKSLAYKGSDIQSIGNASVIGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYESEGIAWEPVQYFNNKIICDLVEEKYKGIISILDEECLRPGEATDMTFLEKLEDTVKNHPHFVTHKFGDQKLRKSLGRDEFRPLHYAGEVNYSVVGFLDKNNDLLFRNLKEVMCDSGNPIVHQCFDRTELTDKKRPETVATQFKNSLSKLMEILMSKEPSYVRCIKPNDAKQAARFDEVLIRHQVKYLGLIENVRVRRAGFAYRRKYEIFLHRYKSLCPETWPNWDGRAQDGVAVLVKSLGYKPEEYKMGRTKIFIRFPKTLFATEDALEERKQGIATFLQARWKGYVQRRNFLHMKHSAINIQSWWRGNIGRKKAAKKRWAVDVVRRFVKGFIYRNNPRCPENEYFLDYIRYSFLMNLRRNMPKSVLDKSWPVPPPSLQEASELLREMCMNNMVWAYCKRISPEMKQQLEQKVVASEIFKDKKDNYPQSVPRLFINTRLGNEEINTKILQNMENQALTYAVPVVKYDRKGYKPRRRQLLLTHNTAYIVEEAKLKQRIDYANLTGISVSSLSDNLFVLHVKCEDNKQKGDVVLQSDHVIETLTKIAITAEKIHNINIIQGSIKFIVGNGKEGIIDFTPGSELLVAKAKNGHLSVVAPRLNSR