Protein
Myeloid differentiation primary response protein MyD88-B
Function
Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Activates expression of target genes in the Spemann organizer region during early embryonic development. Is required for normal axis formation (By similarity).
Sequence
MACGSSMNSFDMNSIPLVALNYTVRHRLCLYLNPNAVVAADWTRLAEEMGYDYLEIRNFDRYPDSTMKLLEDWQKKCFRATVGGLLEMLKKMERNDILTDLAPLIEADCKKYLEKKHGPLPLQDDNVDSSEQYRITKSDDPYGSMPETFDAFICCCAQDILFVQEMISRLEQTDYKLKLCVFDRDVLPGTCLWSITSELIENRCRKMVVIISDDYLDSSECDFQTKFALSLGPGAREKRLIPVKYKPMKRPFPSILRFITLCDNTNPYTKVWFWDKLAKALAR