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myd88-a

Gene
myd88-a
Protein
Myeloid differentiation primary response protein MyD88-A
Organism
Xenopus laevis
Length
283 amino acids
Function
Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response (By similarity). Activates expression of target genes in the Spemann organizer region during early embryonic development. Is required for normal axis formation.
Mass
32.83 kDa
Sequence
MACGSSLDSIDMNSIPLVALNYTVRHRLCLYLNPDAVVAADWTRLAEEMGYDYLEIRNFQRYPDSTMKLLEDWEKKCFRATVGGLLEMLKKMERNDILTDLGPLIEADCMKYLEKKHVPLPIQDDKVDSSEQYRITKSDDPYGSMPETFDAFICYCAQDISFVQEMISRLEQTDYKLKLCVFDRDVLPGTCLWSITSELIENRCRKMVVIISDDYLDSSDCDFQTKFALSLGPGAREKRLIPVKYKPMKRPFPSILRFITVCDYTNPYTKAWFWDKLAKALAR