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mxi1

Gene
mxi1
Protein
Max-interacting protein 1
Organism
Danio rerio
Length
243 amino acids
Function
Transcriptional repressor. MXI1 binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. MXI1 thus antagonizes MYC transcriptional activity by competing for MAX.
Mass
27.643 kDa
Sequence
MSTCPFNDVFNSTDSSMINTFLKNVQVLLEAASYIESAERKDGKCEHGYASTFPSIQHSSYQRQRKFRNKKCNNNHYRSTHNELEKNRRAHLRLCLERLKTLIPLGPECSRHTTLGLLNKAKAHIKKLEEADRKSRYQLESLEREQRHLRRRLDLLRDGGGSLEAERIRTDSMGSTPCSERSDRSDSDQEEMEVDVESTEFSHGELDSVSTASTSDLDDHSSLQSTASDEGYSSCSIKLAFSS
Protein
Max-interacting protein 1: mxi1

Gene
MXI1
Protein
Max-interacting protein 1
Organism
Homo sapiens
Length
228 amino acids
Function
Transcriptional repressor. MXI1 binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. MXI1 thus antagonizes MYC transcriptional activity by competing for MAX.
Mass
26.062 kDa
Sequence
MERVKMINVQRLLEAAEFLERRERECEHGYASSFPSMPSPRLQHSKPPRRLSRAQKHSSGSSNTSTANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAERKSQHQLENLEREQRFLKWRLEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVDVESTEFSHGEVDNISTTSISDIDDHSSLPSIGSDEGYSSASVKLSFTS
Protein
Max-interacting protein 1: MXI1

Gene
Mxi1
Protein
Max-interacting protein 1
Organism
Mus musculus
Length
228 amino acids
Function
Transcriptional repressor. MXI1 binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. MXI1 thus antagonizes MYC transcriptional activity by competing for MAX. Isoform Short, which lacks a segment, has a much stronger suppressive potential and associates with a SIN3 homologous protein.
Mass
25.978 kDa
Sequence
MERVRMINVQRLLEAAEFLERRERECEHGYASSFPSMPSPRLQHSKPPRRLSRAQKHSSGSSNTSTANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAERKSQHQLENLEREQRFLKRRLEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVDVESTEFSHGEADSVSTTSISDLDDHSSLQSVGSDEGYSSASVKLSFAS
Protein
Max-interacting protein 1: Mxi1

Gene
Mxi1
Protein
Max-interacting protein 1
Organism
Rattus norvegicus
Length
228 amino acids
Function
Transcriptional repressor. MXI1 binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. MXI1 thus antagonizes MYC transcriptional activity by competing for MAX.
Mass
26.022 kDa
Sequence
MERVKMINVQPMLEAAEFLERRERECEHGYASSFPSMPSPRLQHSKPPRRLSRAQKHSSGSSNTSTANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAERKSQHQLENLEREQRFLKRRLEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVDVESTEFSHGEVDNISTTSISDIDDHSSLQSIGSDEGYSSASVKLSFTS
Protein
Max-interacting protein 1: Mxi1