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mutM1

Gene
mutM1
Protein
Formamidopyrimidine-DNA glycosylase
Organism
Xylella fastidiosa (strain 9a5c)
Length
271 amino acids
Function
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity).
Similarity
Belongs to the FPG family.
Mass
31.091 kDa
Sequence
MPELPEVETTLRGLLPYLTNQLIYSLTLRRRTLRWDIPSHIESRLPGHRITTVCRRAKYLLIDTNAGGSLIIHLGMSGTLRLLAPETPLRPHDHVDIMLNNRRVLRFNDPRRFGCLLWQEDGQIHPLLQRLGCEPLSDSFNGDYLYQCSRARNVSVKTFLMDQRIVVGVGNIYAAESLFRAGISPLCEADKISLQRYRRLAEVVKDILLYAINRGGTTLRDFLSPDGRPGYFKQELFVYGRQQQPCKQCGSLLRQTTIRQRTTVWCGHCQG

Gene
mutM1
Protein
Formamidopyrimidine-DNA glycosylase
Organism
Xylella fastidiosa (strain Temecula1 / ATCC 700964)
Length
271 amino acids
Function
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity).
Similarity
Belongs to the FPG family.
Mass
31.091 kDa
Sequence
MPELPEVETTLRGLLPYLTNQLIYSLTLRRRTLRWDIPSHIESRLPGHRITTVCRRAKYLLIDTNAGGSLIIHLGMSGTLRLLAPETPLRPHDHVDIMLNNRRVLRFNDPRRFGCLLWQEDGQIHPLLQRLGCEPLSDSFNGDYLYQCSRARNVSVKTFLMDQRIVVGVGNIYAAESLFRAGISPLCEADKISLQRYRRLAEVVKDILLYAINRGGTTLRDFLSPDGRPGYFKQELFVYGRQQQPCKQCGSLLRQTTIRQRTTVWCGHCQG