Protein
N-acetylmuramic acid 6-phosphate etherase 2
Organism
Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Function
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
Similarity
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Sequence
MTNDALIAALSHLVSEGRNPDTMDIDLLSSQEIVERLNQQDKQVPLAVEAVLPQIAQAVDKITAAFKQGGRLIYLGAGTSGRLGVLDASECPPTFGVSDQMVIGLIAGGKEAMFTAQEGAEDNATLGAHDLQQIDFSSKDVLVGIAASGRTPYVIGALEYANDLGATTIALSCNPDSPIAEIAQIAISPVVGPEALTGSTRLKSGTAQKLVLNMLTTASMIRLGKSYQNLMVDVRATNRKLIARAVRIVMQATDCQREEAEALLKESHNNAKLAILMHLTGMNYEQATAKLSQSDGFLRRAMEEHEE