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murQ2

Gene
murQ2
Protein
N-acetylmuramic acid 6-phosphate etherase 2
Organism
Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Length
307 amino acids
Function
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
Similarity
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Mass
32.73 kDa
Sequence
MTNDALIAALSHLVSEGRNPDTMDIDLLSSQEIVERLNQQDKQVPLAVEAVLPQIAQAVDKITAAFKQGGRLIYLGAGTSGRLGVLDASECPPTFGVSDQMVIGLIAGGKEAMFTAQEGAEDNATLGAHDLQQIDFSSKDVLVGIAASGRTPYVIGALEYANDLGATTIALSCNPDSPIAEIAQIAISPVVGPEALTGSTRLKSGTAQKLVLNMLTTASMIRLGKSYQNLMVDVRATNRKLIARAVRIVMQATDCQREEAEALLKESHNNAKLAILMHLTGMNYEQATAKLSQSDGFLRRAMEEHEE

Gene
murQ2
Protein
N-acetylmuramic acid 6-phosphate etherase 2
Organism
Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
Length
300 amino acids
Function
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
Similarity
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Mass
31.429 kDa
Sequence
MKIDLSRLVTESRNPASTEIDTLSTIEMLQVINEEDQKVALAVKAVLPQIAKTVNAITAAFANGGRLVYMGAGTSGRLGILDASECPPTYGTHPDMVIGLIAGGHQAILKAVENAEDDVKMGQDDLKALHLTKHDVVVGIAASGRTPYVLGGLEYAKSIGATTASIACNPECAMAKAADIAILPIVGAEVVTGSSRMKAGTAQKLVLNMLTTGAMIRSGKVFGNLMVDVEATNAKLIQRQTNIVVEATGASKEEAERALNACDRHCKTAILMILADLDAEQAKSRLAAHNGFIRAALNNN

Gene
murQ2
Protein
N-acetylmuramic acid 6-phosphate etherase 2
Organism
Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / NBRC 12200 / NCIMB 9375 / NRRL NRS-1264 / Gibson 46)
Length
298 amino acids
Function
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.
Similarity
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Mass
32.165 kDa
Sequence
MRKTENTNDKSTALDEMNALDIVTLMNEEDHTVPRAITPCLPLIAEAAETIVSRFEQGGRVFTAGAGTSGRIAVLDAAELPPTFSIDESRWTGLIAGGYDAMWMPLEENEDDREKIVADLKAQSFSKDDVLIGVTASGSTPYVLGALSYAKQIGAASVSISCNADTEAGKLSDIAIEVQTGPEIIRGSTRLKAGTAQKMILNMLSTAAMVRLGRVYQNEMVNMRLLNQKLAGRAVTILMNTTGLSEDEALQALKESGNDIKAAIFMTLTNGTLEVARRCLSHENGHLKKAIQYHRKGF

Gene
murQ2
Protein
N-acetylmuramic acid 6-phosphate etherase 2
Organism
Enterococcus faecalis (strain ATCC 700802 / V583)
Length
296 amino acids
Function
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.
Similarity
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Mass
31.757 kDa
Sequence
MNLENLTTERRNENTMGLDEMSVKEALQKMNQEDQKVAMAVGQELAAIEPVVEAIIKSFNQGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVQGLIAGGQKAMTVAVEGAEDSKELGRQDLVDLKLSANDIVVGIAASGRTPYVIGGLEYATTVGAATATVACNKNAEISKYAQMPIEVDAGPEFLTGSTRLKSGTAQKLILNMLSTISMIGIGKVYNNLMVDVKPTNEKLVERSKRIIMEATGCSYEVAELKFVEAEENVKLAIVMILTDSTKEEATQKLIDGNQFIKNTLN

Gene
murQ2
Protein
N-acetylmuramic acid 6-phosphate etherase 2
Organism
Lactobacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)
Length
296 amino acids
Function
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.
Similarity
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Mass
31.441 kDa
Sequence
MNLEKLTTETRNQKTMALDMLSVKEMLELMNQEDQRVPVAVSKELPQIECAVDKIVANFKAGGRLIYMGAGTSGRLGVLDAAECVPTFGTSPEMVQGLIAGGMSAMTVAVEGAEDSIELGQQDLVDLHLTSHDTVVGVAASGRTPYVIGGLDYACEVGATTVSIACNADASISQHAQIPIEVEVGPEILTGSTRLKSGTAQKLVLNMLSTASMVGIGKVYKNLMVDVKPTNEKLVERAKRIIVQATDCSDETAVKVFMTADQNVKLAIVMVLTNMSKAEASVRLDHANGFVRQAVN