Protein
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase
Organism
Oceanobacillus iheyensis (strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954 / HTE831)
Function
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
Similarity
Belongs to the MurCDEF family. MurE subfamily.
Sequence
MELKKLLECLTFYNVNGEVENCEITSLEMDSRKITSGSAFVCITGFTVDGHDYVDQAVKNGASAIFTSKPLMKEYGVPIIQVEDTNRALAMLAVKYYDYPTKHFPLIGVTGTNGKTTVTYLLDKIFEYHQKKAGVIGTIQVKIGEETFPIVNTTPNALELQKTFHVMREKDVKQGIMEVSSHALDMGRVYGCDYDIAVFTNLSQDHLDYHQDIQDYLRAKSLLFAQLGNGYDSEKEKYAIINDDDSSSHLLKRSTAQHVITYSCKKEATIMAKDIELTASGIRFKLHSPLGNITIQSRLMGMFNVYNMLAASAAAIASKVPLNVIQQALESIEGVNGRFEPIVEGQNYSVIVDFAHTPDSLENVLQTIKDFAKRNVYVVVGCGGDRDRKKRPLMAEVALNYADHAVFTSDNPRTEDPQAILDDMTAELDANSGSYEVVVDRKEGIAKAIQSAQKDDIVLIAGKGHETYQIIGHTKYDFDDRDVARNAIKQKGE