mul1a

Mitochondrial ubiquitin ligase activator of nfkb 1-A

341 amino acids

E3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.

38.585 kDa

MEDFPVLEMVCLGSSVALSGLFYYIYRKKRKTVDKLKEAPVMALDAKLIDLLNATPGKCLQYVVVEGTVQPVGEPLRSQFQESSVGVIQKLVLREHKLVWNSLGRIWTDSERVLLQRVNAVPFNLLGLNKSFVRVLCPLEATGPKMEIVHEKFHQATYGFTDLIGQYLSGEKPKGQLETEEMLKVGASLTVVGELILDTDRLLKIRPPTDGSEYFLSSADFETLLMEQEGQAEVWRVFACICALAGVAVLIWTGRRYYRQLKLRWEQENLRREFEGMGTGEREEDNGVENACVICLSNPRGCVLLDCGHVCCCFRCYQALPQPFCPICRQHIKRVVPLYQA