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mtrm

Gene
mtrm
Protein
Protein matrimony
Organism
Drosophila yakuba
Length
219 amino acids
Function
Polo kinase inhibitor required to maintain G2 arrest in the meiotic cell cycle in females. Holds heterochromatically paired homologs together from the end of pachytene until metaphase I. Haploinsufficient locus for homologous achiasmate segregation and may be required for the maintenance of heterochromatic pairings.
Mass
25.205 kDa
Sequence
MENCRTPTNKTQITLNRTPTLKERRWNTLKVNTTNVRCSTPIFGNFRSPNLSPIESMGTKKSPVSPMRFAFKKPPAKAHPHPHQHQHHHHHHKHIHRTQLKPPPFILPKPQEEIIEPEREIKICSSPDTFSDDSNMETSLVVESRRRSIKASNHSYVVNHAANVEQILMHMGLENYVTNFEEAHIDLVKLASMERADLVKIGLNADEDCNRIMDVLQTL

Gene
mtrm
Protein
Protein matrimony
Organism
Drosophila melanogaster
Length
217 amino acids
Function
Polo kinase inhibitor required to maintain G2 arrest in the meiotic cell cycle in females (PubMed:18052611). Holds heterochromatically paired homologs together from the end of pachytene until metaphase I (PubMed:14573476). Haploinsufficient locus for homologous achiasmate segregation and may be required for the maintenance of heterochromatic pairings (PubMed:14573476).
Mass
24.78 kDa
Sequence
MENSRTPTNKTKITLNRTPTLKERRWNTLKVNTSNVRCSTPIFGNFRSPNLSPIENMGTKGKSPVSPMRFATFKKVPTKVHPKQQQQQQHQHCHRTQLKPPPFVLPKPQEEIIEPEREIKSCSSPDTCSDDSNMETSLALESRRRSIKASNHSYVVNHAANVEQILMHMGLENYVTNFEEAHIDLVELASLERADLVKIGLNTDEDCNRIMDVLHTL