mth

Gene

mth

Protein

G-protein coupled receptor Mth

Organism

Drosophila yakuba

Length

517 amino acids

Function

Involved in biological aging and stress response. Essential for adult survival (By similarity).

Similarity

Belongs to the G-protein coupled receptor 2 family. Mth subfamily.

Mass

59.968 kDa

Sequence

MKLFWVKRLLRISTVVVTLLLLQRTNAAIPDCDYYDTVDISAAQKLPNGSYLFEGLLVPANLTAEYEFTILPDDSKQKVDKHIRGCVCKLKPCVRFCCPHNHIMDMNVCAGDMTEEELEVLDPFLNVTLDDGSVVRRHFKKELIVQWDLPMSCDGMFSLDNREKTDQYTLFENGSFFRHHDRVTLNKREYCLQHLTFVDGNESSIRIAPHNCLISPSRMGQTVVMITSLVCMVLTITVYLFVKKLQNLHGKCFMCYMVCLFMAYLLLLLNLWQMSQNFCITAGFLGYFFVMAAFLWLSVISLHLWNTFSGSAHNANRFLSEHRFLAYNTYAWGMAVVLTGITYLADKVVENEDWNPRMGFGGHCWICTQSWSAMLYFYGPMVFLIAFNITMFILTANRIIGVKKDIQKFAHRQERKQKLNSDKQTYTFFLRLFIIMGLTWSLEIGSYISQFNQTWSNVFLVADYLNWSQGIIIFILFVLKRSTLRLLMESIRGEGEEVNDSEEEISLENTKYDRNVL

Protein

G-protein coupled receptor Mth: mth

Gene

mth

Protein

G-protein coupled receptor Mth

Organism

Drosophila simulans

Length

515 amino acids

Function

Involved in biological aging and stress response. Essential for adult survival (By similarity).

Similarity

Belongs to the G-protein coupled receptor 2 family. Mth subfamily.

Mass

59.601 kDa

Sequence

MKTLFVLRISTVILVVLVIQKSYADILECDYFDTVDISAAQKLQNGSYLFEGLLVPAILTGEYDFRILPDDSKQKVASHIRGCVCKLKPCVRFCCPHDHIMDNGVCNDNMSEEELTELDPFLNVTLDDGSVSRRHFKNELIVQWDLPMPCDGMFYLDNREEQDQYTLFENGTFFRHFDRVTLSKREYCLQHLTFADGNATSIRIAPHNCLIVPSITGQTVVMITSLICMVLTIAVYLFVKKLQNLHGKCFICYMVCLFMGYLFLLFDLWQISISFCKPAGVLGYFFVMAAFLWLSVISLHLWNTFRGSSHKASRFFSEHRFLAYNTYAWGMSMVLTGITVLADNVVEDQDWNPRVGEEGHCWIYTQAWSAMLYFYGPMVFLIAFNITMFILTARRIIGVKKDIQNFAHRQERKQKLNSDKQTYTFFLRLFIIMGLSWSLEIGSYISQSNQTWANVFLVADYLNWSQGIIIFILFILKRSTLRLLQESIRGEGEEVDNSEEEISLENTRFDRNVLS

Protein

G-protein coupled receptor Mth: mth

Gene

mth

Protein

G-protein coupled receptor Mth

Organism

Drosophila melanogaster

Length

514 amino acids

Function

Involved in biological aging and stress response. Essential for adult survival. Required in the presynaptic motor neuron to up-regulate neurotransmitter exocytosis at larval glutamatergic neuromuscular junctions (NMJs). Regulates a step associated with docking and clustering of vesicles at release sites. SP/Acp70A and sun are agonists that activate mth in vitro.

Similarity

Belongs to the G-protein coupled receptor 2 family. Mth subfamily.

Mass

59.644 kDa

Sequence

MKTLLVLRISTVILVVLVIQKSYADILECDYFDTVDISAAQKLQNGSYLFEGLLVPAILTGEYDFRILPDDSKQKVARHIRGCVCKLKPCVRFCCPHDHIMDNGVCYDNMSDEELAELDPFLNVTLDDGSVSRRHFKNELIVQWDLPMPCDGMFYLDNREEQDKYTLFENGTFFRHFDRVTLRKREYCLQHLTFADGNATSIRIAPHNCLIVPSITGQTVVMISSLICMVLTIAVYLFVKKLQNLHGKCFICYMVCLFMGYLFLLLDLWQISISFCKPAGFLGYFFVMAAFFWLSVISLHLWNTFRGSSHKANRFLFEHRFLAYNTYAWGMAVVLTGITVLADNIVENQDWNPRVGHEGHCWIYTQAWSAMLYFYGPMVFLIAFNITMFILTAKRILGVKKDIQNFAHRQERKQKLNSDKQTYTFFLRLFIIMGLSWSLEIGSYFSQSNQTWANVFLVADYLNWSQGIIIFILFVLKRSTWRLLQESIRGEGEEVNNSEEEISLENTTTRNVLL

Protein

G-protein coupled receptor Mth: mth