mtd1

Gene

mtd1

Protein

Methylenetetrahydrofolate dehydrogenase [NAD(+)]

Organism

Schizosaccharomyces pombe (strain 972 / ATCC 24843)

Length

320 amino acids

Function

Catalyzes oxidation of cytoplasmic one-carbon units for purine biosynthesis.

Similarity

Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

Mass

35.814 kDa

Sequence

MSNTNKSEPNHSCKVVYASRVAETFVEQLKQHVNLFEFAPKLVGFLSNSDPAARMYADWTNKTCTEIGFQYELREVPKDDLEDAIVEANNDPSVNGIMIYFPVFNDGQDQYLQQVVSPDKDVEGLCHKYVMNMYHNIRHLDPEKTKKSILPCTPLAIVKILEYLGVYNKIINYGNRLYGKTITIVNRSEIVGRPLAALLANDGAKVYSVDIHNVQCFTRGAGIRSKKHDVADTNFKLEDVAPISDVIICGVPSANYKFPSNLVRDGAVCICFSSEKNFDAASLKEHAGIYVPSIGKVTIAMLLRNLIRLTSYQLNKPVDI

Protein

Methylenetetrahydrofolate dehydrogenase [NAD(+)]: mtd1

Gene

MTD1

Protein

Methylenetetrahydrofolate dehydrogenase [NAD(+)]

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

Length

320 amino acids

Function

Catalyzes oxidation of cytoplasmic one-carbon units for purine biosynthesis.

Similarity

Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

Mass

36.24 kDa

Sequence

MSKPGRTILASKVAETFNTEIINNVEEYKKTHNGQGPLLVGFLANNDPAAKMYATWTQKTSESMGFRYDLRVIEDKDFLEEAIIQANGDDSVNGIMVYFPVFGNAQDQYLQQVVCKEKDVEGLNHVYYQNLYHNVRYLDKENRLKSILPCTPLAIVKILEFLKIYNNLLPEGNRLYGKKCIVINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEYSEDLLKKCSLDSDVVITGVPSENYKFPTEYIKEGAVCINFACTKNFSDDVKEKASLYVPMTGKVTIAMLLRNMLRLVRNVELSKEK

Protein

Methylenetetrahydrofolate dehydrogenase [NAD(+)]: MTD1