mqnD

Gene

mqnD

Protein

1,4-dihydroxy-6-naphtoate synthase

Organism

Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)

Length

282 amino acids

Function

Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

Similarity

Belongs to the MqnA/MqnD family. MqnD subfamily.

Mass

30.054 kDa

Sequence

MSADTLQIAYSPCPNDTFVFDALAHGRVPGAPALDVTFADIDITNGMAERGELDVLKVSYAVLPYVLDDWALLPCGGALGRGCGPLVLTREADADLRGRTVAVPSETSTAYLLFRLWAADTVPGGVGEIVVMPFHEIMPAVRDGKVDAGLVIHEARFTYQNYGLHKLADMGEHWEHTTGLPIPLGAIIARRSLGAPALTRLADAVRASVRAAWDDPEASRPYVMEHAQEMDPAVADQHIGLYVNEFTADLGEDGYAAIRGLLTRAAAEGLVPALGPDALAFP

Protein

1,4-dihydroxy-6-naphtoate synthase: mqnD

Gene

mqnD

Protein

1,4-dihydroxy-6-naphtoate synthase

Organism

Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)

Length

272 amino acids

Function

Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

Similarity

Belongs to the MqnA/MqnD family. MqnD subfamily.

Mass

30.034 kDa

Sequence

MEALRLGFSPCPNDTFIFYALVHGRVESPVPLEPVLEDVETLNRWALEGRLPLTKLSYAAYAQVRDRYVALRSGGALGRGVGPLVVARGPLQALEGLRVAVPGRHTTAYFLLSLYAQGFVPVEVRYDRILPMVAQGEVEAGLIIHESRFTYPRYGLVQVVDLGAWWEERTGLPLPLGAILARRDLGEGLIRALDEAVRRSVAYALAHPEEALDYMRAHAQELSDEVIWAHVHTYVNAFSLDVGEEGERAVARLFAEAEARGLAAPSPRPLFV

Protein

1,4-dihydroxy-6-naphtoate synthase: mqnD