Protein
GTP cyclohydrolase MptA 1
Organism
Methanocella arvoryzae (strain DSM 22066 / NBRC 105507 / MRE50)
Function
Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
Similarity
Belongs to the GTP cyclohydrolase IV family.
Sequence
MKFVQLPDVQASNPDVMVGLTRVGVTEVKKMVEITRSDKRPIILIPTFDIFVDLPSYRKGANLSRNLEAIDRTLEEALNQPVYRIEDLCVDVAKRLLETHEYASNAEVRMHGEYMMKKKSPKTGLECQEVYDIYADAIVVRGGIIRKTIGAKVIAMTACPCAQEISKETAFKKLAALGVADNVIAEFLDDMPMPTHNQRGVGTIKIESGNDVKVSIEAIIDIIENSMSSQMYELLKREDERYVVHSAHKNPKFVEDCVRTMAKNLVRKFPSLPDDAVITIEQVNEESIHRHNAFAERMATFGELKKEMLSNGPVL