Protein
Siderophore export accessory protein MmpS5
Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function
Overexpression of the system confers non-target based resistance to azoles, clofazimine and bedaquiline, via an efflux mechanism.
Similarity
Belongs to the MmpS family.
Sequence
MIGTLKRAWIPLLILVVVAIAGFTVQRIRTFFGSEGILVTPKVFADDPEPFDPKVVEYEVSGSGSYVNINYLDLDAKPQRIDGAALPWSLTLKTTAPSAAPNILAQGDGTSITCRITVDGEVKDERTATGVDALTYCFVKSA