mik1

Gene

MIK1

Protein

MDIS1-interacting receptor like kinase 1

Organism

Arabidopsis thaliana

Length

1013 amino acids

Function

Involved in the regulation of procambium maintenance and polarity during vascular-tissue development (PubMed:17570668). Involved in the pollen tube perception of the female signal (PubMed:26863186). Phosphorylates MDSI1 (PubMed:26863186).

Similarity

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

Mass

110.478 kDa

Sequence

MKMKIIVLFLYYCYIGSTSSVLASIDNVNELSVLLSVKSTLVDPLNFLKDWKLSDTSDHCNWTGVRCNSNGNVEKLDLAGMNLTGKISDSISQLSSLVSFNISCNGFESLLPKSIPPLKSIDISQNSFSGSLFLFSNESLGLVHLNASGNNLSGNLTEDLGNLVSLEVLDLRGNFFQGSLPSSFKNLQKLRFLGLSGNNLTGELPSVLGQLPSLETAILGYNEFKGPIPPEFGNINSLKYLDLAIGKLSGEIPSELGKLKSLETLLLYENNFTGTIPREIGSITTLKVLDFSDNALTGEIPMEITKLKNLQLLNLMRNKLSGSIPPAISSLAQLQVLELWNNTLSGELPSDLGKNSPLQWLDVSSNSFSGEIPSTLCNKGNLTKLILFNNTFTGQIPATLSTCQSLVRVRMQNNLLNGSIPIGFGKLEKLQRLELAGNRLSGGIPGDISDSVSLSFIDFSRNQIRSSLPSTILSIHNLQAFLVADNFISGEVPDQFQDCPSLSNLDLSSNTLTGTIPSSIASCEKLVSLNLRNNNLTGEIPRQITTMSALAVLDLSNNSLTGVLPESIGTSPALELLNVSYNKLTGPVPINGFLKTINPDDLRGNSGLCGGVLPPCSKFQRATSSHSSLHGKRIVAGWLIGIASVLALGILTIVTRTLYKKWYSNGFCGDETASKGEWPWRLMAFHRLGFTASDILACIKESNMIGMGATGIVYKAEMSRSSTVLAVKKLWRSAADIEDGTTGDFVGEVNLLGKLRHRNIVRLLGFLYNDKNMMIVYEFMLNGNLGDAIHGKNAAGRLLVDWVSRYNIALGVAHGLAYLHHDCHPPVIHRDIKSNNILLDANLDARIADFGLARMMARKKETVSMVAGSYGYIAPEYGYTLKVDEKIDIYSYGVVLLELLTGRRPLEPEFGESVDIVEWVRRKIRDNISLEEALDPNVGNCRYVQEEMLLVLQIALLCTTKLPKDRPSMRDVISMLGEAKPRRKSNSNEENTSRSLAEKHSSVFSTSPVNGLL

Protein

MDIS1-interacting receptor like kinase 1: MIK1

Gene

mik1

Protein

Mitosis inhibitor protein kinase mik1

Organism

Schizosaccharomyces pombe (strain 972 / ATCC 24843)

Length

581 amino acids

Function

Protein kinase that acts both on serines and on tyrosines. It acts as a negative regulator of entry into mitosis (G2 to M transition). Phosphorylates and inhibits cdc2.

Similarity

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.

Mass

65.934 kDa

Sequence

MDSSTTIPITPTRTPCFFNISSSFNEHSPLNFYDEPIYNFSSGHEENQSHKSSKLTFFKPSNTKRSPHTPMQNNAKAIRLSTTVRHGIFKNSDLDGCSKPFAFSSGLKLSKKIVDASTPIDLKRKRAVTSLSTGLLSKREKWSLWEGNLTNPRSEQPHTPCKKGTKIKLKPPQSPLSPTTSLLARKCKHIDLDTFSRLDHPNSDSSDETFEMEELPSLSYGSEDLLEFCETPCKSQPIFLSSSHVNNWDEKDVPSSLSWTPTSPIFLNINSADDYEEEEDWTSDLRIRFQQVKPIHESDFSFVYHVSSINPPTETVYVVKMLKKNAAKFTGKERHLQEVSILQRLQACPFVVNLVNVWSYNDNIFLQLDYCENGDLSLFLSELGLLQVMDPFRVWKMLFQLTQALNFIHLLEFVHLDVKPSNVLITRDGNLKLGDFGLATSLPVSSMVDLEGDRVYIAPEILASHNYGKPADVYSLGLSMIEAATNVVLPENGVEWQRLRSGDYSNLPNLKDLLLSKEKVQINKVRCAESLQCLLQRMTHPYVDCRPTTQDLLAMPEMIFISEHSQKAAIIYEDHNSWLET

Protein

Mitosis inhibitor protein kinase mik1: mik1