Protein
Adapter protein MecA
Organism
Oceanobacillus iheyensis (strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954 / HTE831)
Function
Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC.
Similarity
Belongs to the MecA family.
Sequence
MRIERVSTDQFKIFLTFDDLIERGFTREDLWHDASNVRSLFSDMMYEASSELGIELEGMLLVQVHLMQAQGMHIFVTQQYEDNSEDEDYIEMKVTLDESKELIFSFMDFEDIISVTSYLDPMGLENIRLYYMEDRYYMILDHIELSRVDKEDIIGVMSEYANPSIVTSHRIEEYGKLIMEENTVQQIKRFFY