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mdm10

Gene
MDM10
Protein
Mitochondrial distribution and morphology protein 10
Organism
Ustilago maydis (strain 521 / FGSC 9021)
Length
646 amino acids
Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
Similarity
Belongs to the MDM10 family.
Mass
68.51 kDa
Sequence
MHDFVSHILRQYFHATNWNEYNSYLHLTSCSSAILDFCVPTGLSLSISASPTPPFFTTYRLGALPNLRAGIGYIYASTDSKIDFGGSSKDVRLKEIIERFRIVEARAPAAFKSKEKEKEYYWLAGDRYPEQEALGDLGKKERGGGEYLVYGCMHVPSARLDALWTKRISPTWQLIVTAVSSPPRYPLNALQNAAIASRSAYSTGAKSTSSSMDRLDSSNPSLSSSTSLSNTGASTAATTAAAAAAAAAAQDTYGLGPPGSTNLQFTLQRDTGRWFTEYSYSIDDALWGFRVLHNFGTPADTASTTLAALSEGAVETSSSASYPQRNGSVLHTGSSSSSEDTEAGGGLRGRFSAGAEVFISTVEKSAGLSTGIRFSTLPDTPQQPLMIAPSFDSSPSPHQASTLASAPSQPPTVITATLNPMMGHLSTAYAARMARDVVVCSRFDFNVYSYESEWTMGAEYWLRKSGGGGGVESVEASDADVPAPMNRIGSTSSIGGLRGHDETRQARFQEEHAMSLREASEAVSQVDGNTGDGGTSVFGLLRDPPALAPSAPSPRATCANSTLSHLLSPITGVLKARISSTSDIRLLWQGRLSHCLVSLGVKADLSGTHGASYSVGGAPASPKMGIVKSIGLEVMYFSQAEDESVE

Gene
MDM10
Protein
Mitochondrial distribution and morphology protein 10
Organism
Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)
Length
523 amino acids
Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
Similarity
Belongs to the MDM10 family.
Mass
58.752 kDa
Sequence
MYTYMEYLQKCFFKTTNWNEDNIFSNINATSQAILDFPIPNGLKVDSSSKTTDYLASSFTLSNFHLINGSLAYLYSLCPLTNTMGTKDVSLQDAIAGFRIIEPMITLRNQPVGPKTKKLRYSNKYNNNNNNNKNINNKKYAMKKDSRNSLLYGRMYFPGSALEAMVIKRINENTQLLVKCVSNPHLERNGTMIVYLQNNTMKYLRELIYSTNESLIGLRFLYNLGNPITKNISPALAPKFDNSVVSVGTELWFAARTMSPGLSTALRYSTRSTSTGKPLTMTLAVNPILGHISSTYTVKTSVASTFCSKYDFNFFSYASNLSLGFELYSYARNKNYLSPVESSMMLEQPTATVPGSLHNQATKPRRESQRQKSEDYISSSDSDYTRMQVKEFGPGGRITSEQKSNDRLPNKVSPIQNKRDRGREHFTNSSSNNSNSNINSNANTNLDAAFEEKVTTAFQNLVNASDFSSVVKVSTSLRDKTVKLLWEGRVKDFLVSTGARIAINPVTNAPEFSKFGINFSYAF

Gene
MDM10
Protein
Mitochondrial distribution and morphology protein 10
Organism
Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)
Length
508 amino acids
Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
Similarity
Belongs to the MDM10 family.
Mass
56.428 kDa
Sequence
MIGFSAFILRNYYAAIGWNEDNLYSSLTRTSSALLDFQLPQSLILQLANSPTPIFFTSYALDALPQLNGSISYITTSMPLDEIGSGRATAFKNVIERFRVFPPPKRPQPKDEVWLGGKRIEGRDYLLYSRLHLPSLHLSGLATTRLTPTLQAHLAFLSQPAHPTSTRPTPPQTPPSHTRQPSEPSTPAPSPTPGNVFISLQHDTGRYCGEYTYSVQDGMVGLRTLYNFGWHGDEESEVDKKERREREGKRIDEEEMMEGGLKGRFSAGGEVYFSAKQRSFGISTGLRFTTVPPTLPLPLNAPVPSPPTTLTLLYNPLIGFLSSAYSAQVSPTVALATRFGVNVYSYESDLSVGGEWWIGRRRGKRGLTTDAEPQLDAESRDPVVTGIEENRELTEKMAQRASLRQVTLRDEIGEDVHAEKELYSPIPAMTDVNAGELAQQISPRLQPQQDLDDERDGVLKARLSGNWQFALLYEARIRNCLVSAGVLADLTGRQHPIRSIGLEVQYFS

Gene
MDM10
Protein
Mitochondrial distribution and morphology protein 10
Organism
Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)
Length
508 amino acids
Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
Similarity
Belongs to the MDM10 family.
Mass
56.456 kDa
Sequence
MIGFSAFILRNYYAAIGWNEDNLYSSLTRTSSALLDFQLPQSLILQLANSPTPIFFTSYALDALPQLNGSISYITTSMPLDEIGSGRATAFKNVIERFRVFPPPKRPQPKDEVWLGGKRIEGRDYLLYSRLHLPSLHLSGLATTRLTPTLQAHLAFLSQPAHPTSTRPTPPQTPPSHTRQPSEPSTPAPSPTPGNVFISLQHDTGRYCGEYTYSVQDGMVGLRTLYNFGWHGDEESEVDKKERREREGKRIDEEEMMEGGLKGRFSAGGEVYFSAKQRSFGISTGLRFTTVPPTLPLPLNAPVPSPPTTLTLLYNPLIGFLSSAYSAQVSPTVALATRFGVNVYSYESDLSVGGEWWIGRRRGKRGLTTDAEPQLDAESRDPVVTGIEENRELTEKMAQRASLRQVTLRDEIGEDVHAEKELYSPIPVMTDVNAGELAQQISPRLQPQQDLDDERDGVLKARLSGNWQFALLYEARIRNCLVSAGVLADLTGRQHPIRSIGLEVQYFS

Gene
MDM10
Protein
Mitochondrial distribution and morphology protein 10
Organism
Saccharomyces cerevisiae (strain RM11-1a)
Length
493 amino acids
Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
Similarity
Belongs to the MDM10 family.
Mass
56.282 kDa
Sequence
MLPYMDQVLRAFYQSTHWSTQNSYEDITATSRTLLDFRIPSAIHLQISNKSTPNTFNSLDFSTRSRINGSLSYLYSDAQQLENFMRNSTDIPLQDATETYRQLQPNLNFSVSSGNTLSSDNTTVDNDKKLLHDSKFVKKSLYYGRMYYPSSDLEAMIIKRLNPQTQFMLKGVSSFKESLNVLTCYFQRDSHRNLQEWIFSTSDLLCGYRVLHNFLTTPSKFNTSLYNNSSLSLGAEFWLGLVSLSPGCSTTLRYYTHSTNTGRPLTLTLSWNPLFGHISSTYSAKTGTNSTFCAKYDFNLYSIESNLSFGCEFWQKKHHLLETNKNNNDKLEPISDELVDINSNSRATKLLHENVPDLNLAVNDIPSTLDIPVHKQKLLNDLTYAFSSSLRKIDEERSTIEKFDNKINSSIFTSVWKLSTSLRDKTLKLLWEGKWRGFLISAGTELVFTRGFQESLSDDEKNDNAISISATDTENGNIPVFPTKFGIQFQYST

Gene
MDM10
Protein
Mitochondrial distribution and morphology protein 10
Organism
Saccharomyces cerevisiae (strain AWRI1631)
Length
493 amino acids
Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
Similarity
Belongs to the MDM10 family.
Mass
56.282 kDa
Sequence
MLPYMDQVLRAFYQSTHWSTQNSYEDITATSRTLLDFRIPSAIHLQISNKSTPNTFNSLDFSTRSRINGSLSYLYSDAQQLENFMRNSTDIPLQDATETYRQLQPNLNFSVSSGNTLSSDNTTVDNDKKLLHDSKFVKKSLYYGRMYYPSSDLEAMIIKRLNPQTQFMLKGVSSFKESLNVLTCYFQRDSHRNLQEWIFSTSDLLCGYRVLHNFLTTPSKFNTSLYNNSSLSLGAEFWLGLVSLSPGCSTTLRYYTHSTNTGRPLTLTLSWNPLFGHISSTYSAKTGTNSTFCAKYDFNLYSIESNLSFGCEFWQKKHHLLETNKNNNDKLEPISDELVDINSNSRATKLLHENVPDLNLAVNDIPSTLDIPVHKQKLLNDLTYAFSSSLRKIDEERSTIEKFDNKINSSIFTSVWKLSTSLRDKTLKLLWEGKWRGFLISAGTELVFTRGFQESLSDDEKNDNAISISATDTENGNIPVFPTKFGIQFQYST

Gene
MDM10
Protein
Mitochondrial distribution and morphology protein 10
Organism
Saccharomyces cerevisiae (strain YJM789)
Length
493 amino acids
Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
Similarity
Belongs to the MDM10 family.
Mass
56.239 kDa
Sequence
MLPYMDQVLRAFYQSTHWSTQNSYEDITATSRTLLDFRIPSAIHLQISNKSTPNTFNSLDFSTRSRINGSLSYLYSDAQQLEKFMRNSTDIPLQDATETYRQLQPNLNYSVSSGNTLSSDNTTVDNDKKLLHDSKFVKKSLYYGRMYYPSSDLEAMIIKRLSPQTQFMLKGVSSFKESLNVLTCYFQRDSHRNLQEWIFSTSDLLCGYRVLHNFLTTPSKFNTSLYNNSSLSLGAEFWLGLVSLSPGCSTTLRYYTHSTNTGRPLTLTLSWNPLFGHISSTYSAKTGTNSTFCAKYDFNLYSIESNLSFGCEFWQKKHHLLETNKNNNDKLEPISDELVDINPNSRATKLLHENVPDLNSAVNDIPSTLDIPVHKQKLLNDLTYAFSSSLRKIDEERSTIEKFDNKINSSIFTSVWKLSTSLRDKTLKLLWEGKWRGFLISAGTELVFTRGFQESLSDDEKNDNAISISATDTENGNIPVFPAKFGIQFQYST

Gene
MDM10
Protein
Mitochondrial distribution and morphology protein 10
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
493 amino acids
Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
Similarity
Belongs to the MDM10 family.
Mass
56.237 kDa
Sequence
MLPYMDQVLRAFYQSTHWSTQNSYEDITATSRTLLDFRIPSAIHLQISNKSTPNTFNSLDFSTRSRINGSLSYLYSDAQQLEKFMRNSTDIPLQDATETYRQLQPNLNFSVSSANTLSSDNTTVDNDKKLLHDSKFVKKSLYYGRMYYPSSDLEAMIIKRLSPQTQFMLKGVSSFKESLNVLTCYFQRDSHRNLQEWIFSTSDLLCGYRVLHNFLTTPSKFNTSLYNNSSLSLGAEFWLGLVSLSPGCSTTLRYYTHSTNTGRPLTLTLSWNPLFGHISSTYSAKTGTNSTFCAKYDFNLYSIESNLSFGCEFWQKKHHLLETNKNNNDKLEPISDELVDINPNSRATKLLHENVPDLNSAVNDIPSTLDIPVHKQKLLNDLTYAFSSSLRKIDEERSTIEKFDNKINSSIFTSVWKLSTSLRDKTLKLLWEGKWRGFLISAGTELVFTRGFQESLSDDEKNDNAISISATDTENGNIPVFPAKFGIQFQYST

Gene
MDM10
Protein
Mitochondrial distribution and morphology protein 10
Organism
Arthroderma otae (strain ATCC MYA-4605 / CBS 113480)
Length
489 amino acids
Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
Similarity
Belongs to the MDM10 family.
Mass
52.21 kDa
Sequence
MLDFMDYIQLAFSDASGWNRDNSYSTLTDTAKALLDFSTPERLRVHLSSLSTPQFATTYTLGTVGLIDGSVSYLFSTIPLDKTPSRSALISLRSLVPGYRQIYPPAVPLDLGLEWTLGSSGNTGAAEQALSNAYEDTGRSERKRKATLLHATLHLPPPTTLTALFLHRPSPTTKVSVALWSSQATNISKSASPQASILTQLFHDTGKYSTEFLFSTDNTLFGFRGLWNFGPDPRDSGGRNIATGNVKREKTSCPQSVALLSAGGEAYYSPTSSVIGLSTGVRFTTLPAAYDARSSSTSPPTLGGAGGSQIPSPISTFPYTLTLTLTPLTGSLSTTYSLLASPNLALSSRFGFNVYSWESEMVAGCELWRNRKKINLHNYNPDGSVDDLAWAKRKLGLLPPLESSDPASSSSSVSPTVSPVTSESVIKLRVDQSLRVRLLWEGRIKDLLVSAGVALGPTSAHTPSISCSGGSSSKGYSWTGVGVSVLYSS

Gene
mdm10
Protein
Mitochondrial distribution and morphology protein 10
Organism
Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255)
Length
485 amino acids
Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. mdm10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the tom40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of tom40 with the receptor tom22 and small TOM proteins. Can associate with the SAM(core) complex as well as the mdm12-mmm1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the tom40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
Similarity
Belongs to the MDM10 family.
Mass
52.397 kDa
Sequence
MLDFMDYIQLSFAEATHWNRDNSYSSLNTTAQSILDFSTPERLRVHLSSLSTPHFATSYTLGTVGLLDGSVSYLFSTVPFDNLPSGSASIPLRKISPGYRQVQAPATPIETWGWDSLLDGVSIPGLTNGSRPEPPIPKDEESIKESEAKRKATLLHASLHLPPPSTLYALFLRRISSNMQLSLAVCSTQGPPQSKSAPQASMLTQLSHDTGKYSNEYLFSTDNALFGWRGLWNFGPDPRYTRDVPPPLSLLSAGAEAYYSPISSLIGMSTGLRFTTLPAATEIPPSSSPSSTRTPISTFPYTLTLTLAPIVGSLSTTYSLRASPNLAFSSRFGFNVYSWESEMVAGCELWRRTKKSDSSSDDDLEWARRKMRMHDFGVSLPGSPASPLLEDPARPEGPVSSNAHTEAETSDSVIKLRIDQSWNVRLLWEGRVKELLVSAGVGLGPGSFSLSPSVSSASGSGSAQSGGGPGMSYWRGVGVSVLYSS

Gene
mdm10
Protein
Mitochondrial distribution and morphology protein 10
Organism
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Length
480 amino acids
Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. mdm10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the tom40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of tom40 with the receptor tom22 and small TOM proteins. Can associate with the SAM(core) complex as well as the mdm12-mmm-1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the tom40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
Similarity
Belongs to the MDM10 family.
Mass
52.714 kDa
Sequence
MREFMNYITNAFYGATGWNEDNKYNELNATSRELIDFPLPRGLRLTLSSLATPHFATSYQLGSVGVVDGSISYLHSSIPLTHIAAQSDKIPLPALLRCYRRLHDLRSPGQQHYILDADPLSGLPPPPQSARALLGAASDAAVAGGALDGGNTDQDLGIYTHSLLYGRLYLPKSLLEGMIIKRFTQALQVQVRAVSEQSLRNGGTILGLVQYDKGKYGLEGLYSTDGGLLGFRGLYNFGGDASSSTCDPWTPTPGENNNNNNNNNNNNNGNAQAGEKERIYGRFSVGGELYYGTLNKSGGMSLGARFATLPAHRGTPLTATLTINPLMGNINATYALLAREYCSLATRVDFNVYSYESEWAVGMELWSNRRPAGFLLGASPSNDFEPEPHPPRKKERSFQAKMEWRLDDPEPEPEPQPTPKTRKNDEYKGVLKARLDNNLRMGLLWEGRAKSLIFSIGTGIDLHKLGEPFRSLGLEVQYSS

Gene
mdm10
Protein
Mitochondrial distribution and morphology protein 10
Organism
Talaromyces marneffei (strain ATCC 18224 / CBS 334.59 / QM 7333)
Length
477 amino acids
Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. mdm10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the tom40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of tom40 with the receptor tom22 and small TOM proteins. Can associate with the SAM(core) complex as well as the mdm12-mmm1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the tom40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
Similarity
Belongs to the MDM10 family.
Mass
50.884 kDa
Sequence
MLEFMDYVQLAFAEATRWNQDNSYSALTATAESLLDFHVPERLQVRLSSLSTPHFATSYTLGTVGLIDGSVSYLFSTVPLNNTPSQSGLIPLRRLVRGYRQIEAPVPPRRNWGWDAIPSPNSLQNIDGAENNDDVVRKATLLHATLHLPPPSTLNALFLRRISPTTQITASLVSTQAPPLVKSAPSAALLAQISHDTGTFSNEYLFSTDNALFGWRGLWNIGLEPAPGKASTDKVSLLSAGAEAYYSPISSLVGLSTGLKFTTLPAASRTPSSSSSGSTPNPISSFPYTLTLTLTPLTGSLSTTYSARASPNLAFSSRFGFNVYSWESEMVAGCEIWRKSPRTEPVEVDDGLEWARRKMGIVKDLAAEKISSLSSSNNPQAIEEDEGDSVIKIRVDQSWNVRLLWEGRVKSLLVTAGVSLGPGSFTALSSIPSSPTSSSAPVAAAGTGSSQSSGGGAAPTSRPSYWQGVGVSILYSS

Gene
MDM10
Protein
Mitochondrial distribution and morphology protein 10
Organism
Candida albicans (strain SC5314 / ATCC MYA-2876)
Length
473 amino acids
Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
Similarity
Belongs to the MDM10 family.
Mass
53.129 kDa
Sequence
MYTYMEYLQKCFYKSTNWNEDNIYSNITATSQALLDFPIPNGFKIDSSSKTTDYSASSFTLSNHHQINGSLAYLYSSIPLTNTMGTKDVSLQDAIAGFRIIEPSVGLRSKLKNNIMSNRSSLLYGRMYFPGSALEAMIIKRLTKNSQLLIKCVNNPHLEKNGTMIVYLQNNTAKYSRELIYSTNEALIGLRCLYNLGDATSHNFTNINPAVIPKFDNSVVSIGTEIWYAARTMSPGLSAALRYSTRSTSTGKPLTMTLAINPIVGHVSSTYTVKTSVASTFCSKYDFNVFSYASNLSLGFELYSYANKKKNSFPSFEHHEIHSSSEENKYLKKHPELQRHHNLHHNLHHQRVPIKSHKYEGNRTIINPIQNLDNVYHINPTLLSSNGSTSTTTNNENTNTSETVTAAFQNLVNESDFSSVFKFSTSLNDKVVKILWEGRLKEFLVSTGVKLSLNPITNTPEFNKLGISFSYAL

Gene
MDM10
Protein
Mitochondrial distribution and morphology protein 10
Organism
Candida albicans (strain WO-1)
Length
473 amino acids
Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
Similarity
Belongs to the MDM10 family.
Mass
53.095 kDa
Sequence
MYTYMEYLQKCLYKSTNWNEDNIYSNITATSQALLDFPIPNGFKIDSSSKTTDYSASSFTLSNHHQINGSLAYLYSSIPLTNTMGTKDVSLQDAIAGFRIIEPSVGLRSKLKNNIMSNRSSLLYGRMYFPGSALEAMIIKRLTKNSQLLIKCVNNPHLEKNGTMIVYLQNNTAKYSRELIYSTNEALIGLRCLYNLGDATSHNFTNINPAVIPKFDNSVVSIGTEIWYAARTMSPGLSAALRYSTRSTSTGKPLTMTLAINPIVGHVSSTYTVKTSVASTFCSKYDFNVFSYASNLSLGFELYSYANKKKNSFPSFEHHEIHSSSEENKYLKKHPELQRHHNLHHNLHHQRVPIKSHKYEGNRTIINPIQNLDNVYHINPTLLSSNGSTSTTTNNENTNTSETVTAAFQNLVNESDFSSVFKFSTSLNDKVVKILWEGRLKEFLVSTGVKLSLNPITNTPEFNKLGISFSYAL

Gene
mdm10
Protein
Mitochondrial distribution and morphology protein 10
Organism
Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)
Length
472 amino acids
Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. mdm10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the tom40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of tom40 with the receptor tom22 and small TOM proteins. Can associate with the SAM(core) complex as well as the mdm12-mmm1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the tom40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
Similarity
Belongs to the MDM10 family.
Mass
50.462 kDa
Sequence
MLEFMDYVQLAFAEATRWNQDNSYSSLTAIAESLLDFHVPERLQVHLSSLSTPHFATSYTLGTVGLIDGSVSYLFSTVPLNNTPSQSGVIPLRRLVRGYRQIEAPVPPIRNWGWDAIPSHDSSQIIDSADINQDDIVRKATLLHATLHLPPPSTLNALFQRRISPTTQITAALVSTQGPPLIKSAPSAALLAQISHDTGTFSNEYLFSTDNALFGWRGLWNIGLDPSPGKQSTDKVSLLSAGAEAYYSPISSLVGLSTGLKFTTLPAAGRALSSSSSSSPGSNPSPISSFPYTLTLTLTPLTGSLSTTYSARASPNLAFSSRFGFNVYSWESEMVAGCEIWRKSPRTQPAEADDGLDWARRKMGIVKERAAEKISALSSSSSTPQAVEESEGDSVVKIRVDQSWNVRLLWEGRVKSLLVTAGVSLGPGTFTALSSGPASPTSSSAPVAMAGAPPTSRPSYWQGVGVSILYSS

Gene
MDM10
Protein
Mitochondrial distribution and morphology protein 10
Organism
Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968)
Length
471 amino acids
Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
Similarity
Belongs to the MDM10 family.
Mass
52.585 kDa
Sequence
MYTYMEYLQKCFYKTTNWNEDNIFSNITATSSALLEFPIPNGCKVDLSSKATEHSASSFTLSNYHSINGSLAYLYSSIPLRNTMGTKDISLQDAISGFKMLELNSSTTNALQNPVYKNTHDSLLYGRMYFPGSALEAMIIKRISPQTQLLIKCINNPHLDKNGTMIVYLQKNAPKLSREFIYSTNEALFGFRCLYNMGSSESNLNRSINNSNLIPKFDNSVISIGTEIWYAALSMSPGLSTAFRYSTRSTSTGKPLTMTFACNPILGHISSAYTVKTSVASTFCSKYDFNVFSYASNLSLGFEIYNYSSSNTSNSAATPPRIKNSDSQVLSNNSTDSKGTVHIRSPDVLDYKNHSNVIISPIQTFDNYYHINPTLLPSTKNEFEEVRPPPLESQVDSNNETAMTAFENLVNESDFSSVIKLSTSLNDKMLKLLWKGRCKDFLVTTGVKMILNPITNTPEFNRFGISFSYAC

Gene
MDM10
Protein
Mitochondrial distribution and morphology protein 10
Organism
Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)
Length
469 amino acids
Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
Similarity
Belongs to the MDM10 family.
Mass
52.747 kDa
Sequence
MYTYMEYLQKCFYKSTNWNEDNIFSNITASSSAILDFPIPTGFKLDSSNKSTEYSASSFTLSNYHSINGSLAYLYSSVPLRNTMGTKEISLQDALVGFRIIEPSSNNHKQLSSSKRHDRSSLLYGRMYFPGSALEAMIIKRISAHTQLLIKCINNPHMDKNGTMIVYLQKNAPKYSREFIYSTNESLIGFRCLYNLGNSDNSLNTALIPKFDNSVISIGTELWYAARTMSPGLSTAFRYSTRSTSTGKPLTMTLAVNPILGHLSSTYTVKTSVASTFSSRYDFNFFSYASNLSLGFELYNYSRENPVHSFANRSVNLSSEENRFLSHQDRKVRGQHGGNTIPIRSHTSIAQKDHSNMIINPIQNLDNYYHINPTLLPEKKKLLDEVELAAHLSSENSESVTTAFQNLVNESDFASVVKFSTSLNDRMVKILWEGRVKDFLVSTGVKVGMNPVTNAPEFNRFGVSFSYAC

Gene
MDM10
Protein
Mitochondrial distribution and morphology protein 10
Organism
Blastomyces gilchristii (strain SLH14081)
Length
468 amino acids
Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
Similarity
Belongs to the MDM10 family.
Mass
51.029 kDa
Sequence
MRDFMDYIQLAFYDASKWNRDNSYSQLTTTANALLDFSTPERLKVNLSSLSTPHFATTYTLGTVGLIDGSISYLFTTIPLHDTPSRSTLIPLRKLVPGYRQIYPPSLPPAFPAADGRDGDLAIGGTEGDLKKKATLLHATLHLPPPTTLTGSFLRRLSPTTQLSLAFCSSRAPASKSAPQATLVTQILYDTGKYNSEFLFSTDNALFGFKGLWNFGPDPRKQNQNGGDPAREPCRSLLSLLSAGGEVYYSPVSSVVGLSTGLRFTTLPAATENPHSTFPYTLTLTLTPLTGSMSTTYSLLASPNLAFSSRFGFNVYSWESEMVAGCELWRRSKKLHTLQRNSSPLFAVDDLTWARRKMGLQDAAVSVHSERDDLPGIQRYDHDMHHHTQRPHASDSVIKVRVDQSWNIRALWEGRVKELVVSAGIALGPKSRSSLSYASSLAASGPGAAGGLSSYGWKSVGVSVLYSS

Gene
MDM10
Protein
Mitochondrial distribution and morphology protein 10
Organism
Ajellomyces capsulatus (strain G186AR / H82 / ATCC MYA-2454 / RMSCC 2432)
Length
467 amino acids
Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
Similarity
Belongs to the MDM10 family.
Mass
50.898 kDa
Sequence
MLGFLDYIQLAFSDASKWNRDNSYSQLTTTANALLDFSTPERLKVNLSSLSTPHFATTYTLGTVGLIDGSISYLFTTVPLRDTPSRSTLIPLRKLVPGYRQISAPSLPPELPTVDGRDGDLAIGETQGILKKKPTLLHATLHLPPPTTLTGLFLRRLSPTTQLSLAFCSSRASTPKSAPQAALVTQILHDTGKYSSEFLFSTDNALFGFKGLWNFGPDPRKQNQQGDLARDSRRSLLSLLSAGAEAYYSPVSSVVGLSTGLRFTTLPAATESPHFTFPYTLTLTLTPLTGSMSTTYSLLASPNVSFSSRFGFNVYSWESEMVAGCELWRRSSNNRLHDDKSQRDSALFGVDDLTWARRKMGLPDTAPSRNRECDDLPPPRYDNYYHQRSPHASDSVIKVRVDQSWNIRALWEGRVKELLVSAGVALGPTPRSSLSYASSSAVGGVGAAGGLSSYGWKSVGVSVLYSS

Gene
MDM10
Protein
Mitochondrial distribution and morphology protein 10
Organism
Ajellomyces capsulatus (strain NAm1 / WU24)
Length
467 amino acids
Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
Similarity
Belongs to the MDM10 family.
Mass
50.838 kDa
Sequence
MLDFLDYIQFAFSDASKWNRDNSYSQLTMTANALLDFSTPERLKVNLSSLSTPHFATTYTLGTVGLIDGSISYLFTTVPLRDTPSRGTLIPLRKLVPGYRQISAPSLPPGLPTVDGRDGDLAIGDTQGILKKKPTLLHATLHLPPPTTLTGLFLRRLSPTTQLSLAFCSSRASTPKSAPQAALVTQILHDTGKYSSEFLFSTDNALFGFKGLWNFGPDPRKQNQQGDPARESCRPLLSLLSAGAEAYYSPVSSVVGLSTGLRFTTLPAATESPHFTFPYTLTLTLTPLTGSMSTTYSLLASPNVSFSSRFGFNVYSWESEMVAGCELWRRSSNNRLHDDKSQRDSPLFAVDDLTWARRKMGLPDTAPSRNRECDDLPPPRRDNYHHQRSPHASDSVIKVRVDQSWNIRALWEGRVKELLVSAGVALGPTPRSSLSYASSSAAGGVGAAGGLSSYGWKSVGVSVLYSS

Gene
MDM10
Protein
Mitochondrial distribution and morphology protein 10
Organism
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
Length
465 amino acids
Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
Similarity
Belongs to the MDM10 family.
Mass
52.26 kDa
Sequence
MIEYMEYVLRQFERTTSWDRDYSYENITATSDNLLQFEIPDSLNLQISNQSTPNTFNTFELSNRSIINGSLSYLYTDCGQLDKIVQNSLKVPLQQRVDTYQCLRPGRTLGTSFRSQMLLYGRMYWPGSILEAMYCKRLTPQSQLVLKSLLSAAGESSILTLYWQRNAPWGSQDIVFSTNELLLGYRFLHNLSPGRSHEGSPHGQSTLSLGAEFWLGISNLLPGCSTALRYCTHATNTGKPITLTLSLNPLFGHISSSYSVKFSPGTTFCSKYDFNVYSIESNLSFGCEFWKSSAAAHKQATNEEETSIEVATETPVSDPRYCGAVPGARSFDQIRPFAELPSDNQLYHQLMMPNSSNALIDNVNLPFPSPLLRYPPEKSVTDKFAAMIDATQFTSVLKMSSSLRDKNLRLLWEGKYKGFLVSAGAELTTIPLEAPKTINEITAQQVPRPLWLRPAKFGIQIQYST

Gene
MDM10
Protein
Mitochondrial distribution and morphology protein 10
Organism
Candida dubliniensis (strain CD36 / ATCC MYA-646 / CBS 7987 / NCPF 3949 / NRRL Y-17841)
Length
463 amino acids
Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
Similarity
Belongs to the MDM10 family.
Mass
51.921 kDa
Sequence
MYTYMEYLQKCFYKSTNWNEDNIYSNITATSQALLDFPIPNGFKIDSSSKTTDYSASSFTLSNHHQINGSLAYLYSSIPLTNTMGTKDVSLQDAIAGFRIIEPSVGLSSKLTNNIIQNRSSLLYGRMYFPGSALEAMIIKRITKNSQLLIKCVNNPHLEKNGTMIVYLQNNTAKYSRELIYSTNEALIGLRCLYNLGNDATSHNFPHVNPAVIPKFDNSVISIGTELWYAARTMSPGLSAALRYSTRSTSTGKPLTMTLAINPIVGHISSTYTVKTSVASTFCSKYDFNVFSYASNLSLGFELYSYANKKKNTFPSFEHHEIYSSSEENKYLKKHPELQRHHRVPIKSHKYQGNRTIINPIQNLDNVYHINPTLLSSTTNSPTNNDNSNTSETVTAAFQNLVNESDFSSVFKFSTSLNDKVVKILWEGRLKDFLVSTGVKLSLNPITNTPEFNKLGISFSYAL

Gene
MDM10
Protein
Mitochondrial distribution and morphology protein 10
Organism
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)
Length
460 amino acids
Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
Similarity
Belongs to the MDM10 family.
Mass
52.995 kDa
Sequence
MLDYMDYVQQCFDSAGRWKRQNSYGEVTQTPRNLIDFKIPDAVNLQVSNRSTKYSYNSLQLSTRQSINGSLTYLYTNLDAVEGLVKNTEELPLHDIVQTYELPAVTHHRKEKTNFHKCSLFYGKIFYPSSDVEAMMIKRFSPMNQVIVKCLSSLKENVNIFTAYFQRNSEKNFQELIVSSNDLLCGYRISHHFLRTPSKLNSSLYNNSSLFFGAEFWLGMISLNPGCSTSLKYCTHSANTGRPLTLTLSWNPLFGHISTTYSAMTSSSSTFCAKYDFNIYSIESNLSFGIELWRKTGALFKSEDSVEANRKEYEQNFYISHDHNLLPSKYGYDHEYNISDGKLSKEHKRNKIIKDLNHAFSTSLQKIDKEKTRIENFGNIIRNSHFTSVFKASTSLRERNLKFLWEGEYKNFLLSAGTELRVLKAEESELRRTSGQSSNSLLNEFSLQPLKFGVQIQFSS

Gene
MDM10
Protein
Mitochondrial distribution and morphology protein 10
Organism
Clavispora lusitaniae (strain ATCC 42720)
Length
459 amino acids
Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
Similarity
Belongs to the MDM10 family.
Mass
51.285 kDa
Sequence
MYTHMEYLQRCFYKSTSWNEDNIYANVTATSQALLDFSIPSGAKLDVSTQATDHSASSMSLSNMHTINGSLAYLFSSTPLKNTMGTRDVSLQDAVAGFRIIEPFFSGTHTKTDSSDVNRASLLYGRMYFPGTALEAMLIKRISASAQLLVKCINNPHIRKGGTMIVYLQENTPRFSREYIYSTNEALFGFRCLYNFGKPTKISPALIPKFDNSVVSVGAEFWYAALGMSPGLSTAVRYSTRSTSTGKPLTMTLACNPILGHISSTYNVKTSVSSTVCSKYDFNWFSYASNLSIGFELYNFFKPSHVFKHYHADQRRNPSIHHDTLAPVADPYVLGTRPTNNSVSYAFPEKPRKRVVNSIQNLDDYYHINPSRLHRSPAYDVDDDVSGRSVMEAFQNSVNESNFSSVLKGSTSLSDRMVKLLWVGRYKDFLVSTGIKVNLNPFTNLPEINKIGVTFSYAC

Gene
MDM10
Protein
Mitochondrial distribution and morphology protein 10
Organism
Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)
Length
458 amino acids
Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
Similarity
Belongs to the MDM10 family.
Mass
51.173 kDa
Sequence
MIDYMEHVLRSFEQCTGWNRDNSYENVTATSENLLSFRVPSGVKFQVSNKSTPNTFTTFELSNNKVINGSLAYLYTNCQGLENYVSNSRDILLQEASETYRQIRPLYPCHSLRSSSDGAKEFGPSSLWYGRMYYPTSTLEAMVVSRSSAQTQFVAKCISSLANASVLTLYWQKDSGQNCQEWVASTNEGLLGYRILHNFVGSQSKLNTSLYNDSSLSVGGELWFGVLNTTPACSTTLRYCTHSANTGKPLTLTLSWNPLFGHVSSTYSVKTSSGATFSSKYDFNLYSIESNLSFGCDLWRRGHTKQLDQRRTEPLDAPNTNSSVFSKERVQKKQGPKEDSPMFYHLMAGSTSSQKLIEDLNVTFASSLQKLTKEKSTIQRFENSLIDANFASVWKLSTSLRHKNLRVLWEGKYKGFLISAGAEFTGAPLELPSNLAGESKTPALIRPGKFGIQLQYST

Gene
MDM10
Protein
Mitochondrial distribution and morphology protein 10
Organism
Coprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003)
Length
455 amino acids
Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
Similarity
Belongs to the MDM10 family.
Mass
50.205 kDa
Sequence
MHPFASYVLRTYYKATGWNEDNLYANLTRSSNAVLDFTVPRGLHFTVSKSPNPLFKTTYSMTAMPSLSGSLGYIFTSCDLNVLSSGTVRFKDMLDRFKVYDQPRRPEGKEEEWLAGERVDTRDYLLYGRFYLPSGRLDALYSTRLSPTVQLSVAAISDPISGTPVDGRRRTDPSNIMLNLQHDVGKWCTEYTYSAEDSMWGVRFLHNFGRLAPSSWETTNGENGTNTSAPGNASNSRAGVKRVDEEDAVEGGLRGRVSVGAELYFSAKERSAGVSTGIRFSTMPDATPPSAQIPPPSPFTPDPTTSGPSPALLNPRPYPQPPTTITALFNPMLGHIQSAYTARVSRDLALATRFDFNVYSYDSEWTMGAEWWLRRSPRSSTDSGEEGAEKPSYPSPLGEVHGVVKARASTNNDVSLMWEGRIRQMLVSLGVVSDLSSRAKPIKAIGIEVSYFSSE

Gene
MDM10
Protein
Mitochondrial distribution and morphology protein 10
Organism
Candida tropicalis (strain ATCC MYA-3404 / T1)
Length
454 amino acids
Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
Similarity
Belongs to the MDM10 family.
Mass
51.077 kDa
Sequence
MYTYMEYLQKCFYKSTNWNEDNIFSNITATSQAILEFPIPNGFKIDSSSKTTDYSASSFTLSNNHQINGSLAYLYSSVPLKNTMGTKDVSLQDAIAGFRIIEPMVRLQPKFNNKAPHSKSSLLYGRMYFPGSALEAMIIKRISENTQLLIKCVNNPHLSKNGTMIVYLQNNTAKYSREFIYSTNESLIGLRCLYNLGTPTSSSTVSSFNPRTIPKFDNSVVSIGTELWFATRSMSPGLSGALRYSTRSTSTGKPLTMTLAINPILGHISSTYTVKTSVASTFCSRYDFNVFSYASNLSLGFELYSYANKKRSDFYNHEIYSSSEENKYLKQHPELQKHHRVPIRAYKHHDNRTIINPIHNLDNVYHINPTLLSTTSGSGHTSETVTTAFQNLVNESDFSSVLKFSTSLNDKVVKILWEGRLRDFLVSTGVKLSLNPVTNTPEFNKLGISFSYAL

Gene
MDM10
Protein
Mitochondrial distribution and morphology protein 10
Organism
Uncinocarpus reesii (strain UAMH 1704)
Length
452 amino acids
Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
Similarity
Belongs to the MDM10 family.
Mass
49.118 kDa
Sequence
MIDFIDYIQLSFSDATRWNRDNSYTALTDTANALLDFSIPERLRVHLSSLSTPQFATTYTLGTVGLIDGSISYLFSTLPLQTTQSRSTLIPLRKLVPGYRQIHPPLAPESWDSDGPGHEGSDGQEDETTPWKRRRETLLHAILHLPPPTTLNGLFLRRLSPTTQLSVAVCSTQAKPLSKSTPQASILTQLSHDTGKYSAEFLFSTDNALLGFKGLYNFGPDPRDRTNAQRPQRASQSVSLLSAGGEMYYSPLSSVVGLSTGLRFTTLPAASETLHSPSSSAYPAPSPISTFPYTLTLTLTPLTGSLSTTYSLLASPNLAFSSRFGFNVYSWESEMVAGCELWRQKRKPYPYVSGEKDDLAWAKRKMGLLPPLPAPPTPAKRMDLTAGAGESVESDSVIKLRVDQSLNIRLLWEGRVKDLLVSAGVGLGPTSLSTGGAAYGWTGVGVSVLYST

Gene
MDM10
Protein
Mitochondrial distribution and morphology protein 10
Organism
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
Length
452 amino acids
Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
Similarity
Belongs to the MDM10 family.
Mass
51.784 kDa
Sequence
MLEYMDYVLRQFEECTSWNKDNSYENIVGTSRNILQFDIPTALKVQVSNRATPYSYNTLELTNNKTINGSLTYLYTNCENLDQFIEGSSSVHLQQMTQSFRYIEPYYHHYKNNSKLEVPKVPELPISLAYGRMFYPSSSLEAMYIRRFPNYYQFILKCSSSKSGSSILTMYLQKNTGINCQELIFSTNEALLGYRFVHNFVSAGSKSNLSLYNNSSLSIGSEIWCALLNLSPGCSTTLRYCSHATNTGKPLIFTLSLNPLYGHVSSTYSIKTHENLTFCTKYDFNIYSIQSNLTLGMELWKNSSSIPVERPSEPVETIEDWPQLSHDKTPMYYHLLTRTENSGASSQRLLKDLNLTFQSSLQKINKERNVIENFNERYSEANFTQVFKVSTSLRDMNLRLLWEGKIRGFLISAGAELTQPPEISTNGLDSLEHQNWSLISPSKFGIQLQYSA

Gene
MDM10
Protein
Mitochondrial distribution and morphology protein 10
Organism
Paracoccidioides lutzii (strain ATCC MYA-826 / Pb01)
Length
450 amino acids
Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
Similarity
Belongs to the MDM10 family.
Mass
48.876 kDa
Sequence
MCDFMDYIQLAFYDASKWNRDNSYSRLTTTANALLDFSTPERLKVNLSSLSTPHFATTYTLGTVGLIDGSISYLFTTIPLHNTPSRSSLIPLRKLVPGYRQIYPPSIPIEYPTANDHSGIPAAVRSKADNPKMKPTLLHATLHLPPPTTLTGLFICRLSSTTQLSLAVCSSRAPASKSAPQATLLTQIFHDTGKYSSEFLFSTDNALLGFKGLWNFGPDPRKPTRGDPASQRSRPLLSLLSAGGEVYYSPVSSVVGLSTGLRFATLPAATENAHSAFPYTLTLTLTPLTGSMSTTYSLLASPNLAFSSRFGFNVYSWESEMVAGCELWRRSKSKSQNIYPSAVDNLAWARLKMGVPDTAVSVNPEHELSYFHKEGHNSSHASDSVIKVRVDQSWNIRALWEGRVKELLISAGVALGPASRSTLSYASPVAPGGLSSYGWKSVGVSVLYAS

Gene
MDM10
Protein
Mitochondrial distribution and morphology protein 10
Organism
Ajellomyces dermatitidis (strain ER-3 / ATCC MYA-2586)
Length
449 amino acids
Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
Similarity
Belongs to the MDM10 family.
Mass
48.708 kDa
Sequence
MRDFMDYIQLAFYDASKWNRDNSYSQLTTTANALLDFSTPERLKVNLSSLSTPHFATTYTLGTVGLIDGSISYLFTTIPLHDTPSRSTLIPLRKLVPGYRQIYPPSLPPAFPAADGRDGDLAIGGTEGDLKKKATLLHATLHLPPPTTLTGSFLRRLSPTTQLSLAFCSSRAPASKSAPQATTDNALFGFKGLWNFGPDPRKQNQNGGDPAREPCRSLLSLLSAGGEVYYSPVSSVVGLSTGLRFTTLPAATENPHSTFPYTLTLTLTPLTGSMSTTYSLLASPNLAFSSRFGFNVYSWESEMVAGCELWRRSKKLHTLQRNSSPLFAVDDLTWARRKMGLQDAAVSVHPERDGLPGIQRDDHDMHHHPQRPHASDSVIKVRVDQSWNIRALWEGRVKELVVSAGIALGPKSRSSLSYASSLAASGPGAAGGLSSYGWKSVGVSVLYSS

Gene
MDM10
Protein
Mitochondrial distribution and morphology protein 10
Organism
Postia placenta (strain ATCC 44394 / Madison 698-R)
Length
449 amino acids
Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
Similarity
Belongs to the MDM10 family.
Mass
49.24 kDa
Sequence
MHPFASYVLRSYYRGTGWNEDNLYANLTRSSNAILDFSVPRGLHFSISKSPNPLFKTTYSMNALPSLNGSIGYIFTSCELDVKGSGDVRFKDMVDRFRVYDQPRRPEGKEEEWLAGERVDTRDYLLYGRVYIPTGRLDALYSTRLSPTLQAMVAAISDPRSSLFAESPRGIAAPSSNIMFSLQHDTGKWCTEYTWSAEDGMWGVRCLHNFGKVGGPSEPVEDSEKSTAAPTKTRSGVKRIDEEDAMEGGLKGRISAGAEFYFSAKEKSAGVSTGIRFTTLPDATPPSFQLPSSSPTQPSLLAHGAPSQPPTTITALFNPMLGHMSGAYSARVSRDLSMSSRFDFNVYSYESEWSIGAEWWTRRGRGMFTSNPPAADTSEKTPSSPPALEAVGDVTGVVKARASTTTDFSLMWEGRLHNMLVSLGIVSNLTSRSKPIKAIGLELSYFSSG

Gene
MDM10
Protein
Mitochondrial distribution and morphology protein 10
Organism
Zygosaccharomyces rouxii (strain ATCC 2623 / CBS 732 / NBRC 1130 / NCYC 568 / NRRL Y-229)
Length
448 amino acids
Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
Similarity
Belongs to the MDM10 family.
Mass
51.684 kDa
Sequence
MLDYMDYVQRQFEKSTDWNYDNSYANILASSRNILDFPVPNQFKFQLSNNSTPHTFNTMEVFSRKIFNGSMTYLYTDAENMDKLVHDSNSISLQDVTDTYRYVQPYYTHKPSSNGDNHVRSLYYGKMSYPSPNLEAMLIKRLNESTQLTLQCVSSFNGFNILTGYWQHDTGRNRHEVIMSTNDLLCGYRYLHNFLGTPSKLKTSLYNNFSLSLGGEVWLGIVTLSPGCSTTLRYCTHSPTTGRPQTLTLTWNPLFGHISSTYTAKTSSSSTFSTKYDFNLYSIESNLSFGCEFWRRGYQESSPQLQEQINGHASEPKDRIMYYHMMAPDSRNSISPRANSPQERQLLEDLTIAFSSSLKKIDKEKSMIEQFENRINQSNFTSVWKLSTSSKDKNLRLLWEGKFKGFLLSAGTEFCKTNPRNEINEVPSTENKLTFYPNKFGIQLQYST

Gene
MDM10
Protein
Mitochondrial distribution and morphology protein 10
Organism
Coccidioides immitis (strain RS)
Length
448 amino acids
Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
Similarity
Belongs to the MDM10 family.
Mass
48.648 kDa
Sequence
MIDFMDYIQLTFSDATHWNRDNSYTALTDTANALLDFSIPERLRVHLSSLSTPQFATTYTLGTVGLIDGSISYLFSTLPLESTPSRSTLIPLRRLVPGYRQIHPPLAPESPNESRHAEPNERSEKALQSWRKETMLHATLHLPPPTTLNGLFLRRISPTTQLSLAVCSTQATPLSKSTPQASILTQLSHDTGKYSAEFLFSTDNALLGFKGLWNFGPDPRHAATAQRPRTASQSVSLLSAGGEMYYSPLSSVVGLSTGLRFTTLPAASESTHSSSSTHPAQSPISTFPYTLTLTLTPLTGSLSTTYSLLASPNLAFSSRFGFNVYSWESEMVAGCELWRRKKKRHASTLSDKDDLSWAKRKMGLLPPLPPSPVKGTSASAVTPAGEQKESDSVIKLRVDQSLNVRLLWEGRVKDLLVSAGVGLGPSLPSIGGTTYGWTGVGVSVLYST

Gene
MDM10
Protein
Mitochondrial distribution and morphology protein 10
Organism
Podospora anserina (strain S / ATCC MYA-4624 / DSM 980 / FGSC 10383)
Length
448 amino acids
Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
Similarity
Belongs to the MDM10 family.
Mass
48.963 kDa
Sequence
MREFMQYVRNAFYGATGWSEDNSYKDLNVTARELIDFPLPRGIRLSLSSLATPHFATSYQLCNVGVVDGSISYLHSSVPLAAVPAQSNKIPLGALMRSYRGLHQLGSRGGTPWSWETGPQIGTIPQVPAVADMGQIPNKDKSSLLYGRLYLPQSLLEAMVIKRFSPALQVQISAVSEQSLRNGGTMLSVVQYDRGKYGVEGLYSTDGGLLGLRGLYNFGGDASVAVMSSQNGTGSPESTEKERIYGRFSAGGEMYYGTLNKSGGMSLGARFATLPTHKGTPLTATLTINPLMGNINTTYAVLAKDFLAMATRMEFNAYSYESDWAVGLELWSNRRPAGFLLGAEPSLDLESDQPELPSKKERSFQAKMEWRLDDPEPEPEPVKIAEKPTEGKEEYLGVFKARLSSNLDLGLVWEGRAKSLIFSLGTGVDLQRLGEPFRSLGLEVQYSS

Gene
MDM10
Protein
Mitochondrial distribution and morphology protein 10
Organism
Komagataella phaffii (strain GS115 / ATCC 20864)
Length
445 amino acids
Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
Similarity
Belongs to the MDM10 family.
Mass
50.755 kDa
Sequence
MLEYMEYLEQCFAKNSQWDYNNLYEHVLDSSASILQFKIPHGFKFSVSSSSSPYNYNSISFENRGKGRLNGSLAYFYTTQELSNYKTSKNIPLQDVIDSYRLVNIPKNDRSYTDNEESKRPWLLYGRMYLPSQSMEAMAIKRLTANTQLMLKGVNILNPTPTPFNNKLTSLSFYLQSNYYKWSREAIFLSSDALFGLRFLYNFGNSTNPQCTPSIDSNNISTLSLGTELWYGAMNMTPGLSTTLRYTSFSVTGNPLTFTLACNPILGSVSTTYSIKTNVFTTLCSKFDFNFYSYESDLTIGCDLWRFGNNEDVPDSNPTPLPSKERELFIPLHDHQLVFPEQEKAKTISNEPKDYESDLLLKFLEIQGIKTARQSVATINNFTQKIKNAPFTSALKLNTSLKNHTVNLMWEGKYNDFLLSTGCSLNLDLKRPNVDGFGLQIQYSS

Gene
MDM10
Protein
Mitochondrial distribution and morphology protein 10
Organism
Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
Length
443 amino acids
Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
Similarity
Belongs to the MDM10 family.
Mass
48.792 kDa
Sequence
MRQFEDYVLESFDHTTGWYQDNSYESLNRTADQLMQFRLPTGLKLSFSSLATPNFSTSYHLGAGGRFDGSICYLFSSVPLKNVVSSSESIPLTALLRSYRQVQDLPPFQPSHGAVPPAPTPTPGERLQEFVKQPWLVFGRMFLPESMLEAQVVKRASPNLRFQVKGVSQADLPNGGTILGSVQYTKPRYGVAGLLSTDGGLLGFRGLYNFGGDTTPTTSSPRAVGGDENGGANGCDERERIYGRFSAGGELYYGVLNKSAGASLGVRFATLPAHSGTPLTATFTLAPLMGNISSSFAVMARQSCSLATRFDFNVYSYESDWTIGMELWGKGRMAGLIDRRLEEEEAQIVPVDMGPAEKKRERSFQAKMEWRLDEDDETEPPLPNKREEEFSGVLKARMDQHSKVGLLWEGRLKSLIFSLGTSVNLSKPEQSFRSLGLAIQYSS

Gene
MDM10
Protein
Mitochondrial distribution and morphology protein 10
Organism
Laccaria bicolor (strain S238N-H82 / ATCC MYA-4686)
Length
439 amino acids
Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
Similarity
Belongs to the MDM10 family.
Mass
48.646 kDa
Sequence
MHPFASYVLRSYYKATGWNEDNLYANLTRSSNAILDFTVPRGLHLTVSKSPNALFKTTYSMTAMPSLHGSVGYIFTSCDLDVKSSGNVRFKNMIERFKVYDQPRRPEPKEEEWLAGEQVQKRDYLLYGRFYLPTGRLDALYSTRLSPTVQALVAAISDPPSNIPSELRDRNGDPSNIMLNLQHDVGKWCTEYTWSAEDGMWGVRVLHNFGRLGMSDAVEDGGGGKGDRTVKVKRVDEEDAVEGGLKGRVSMGAELYFSAKERSAGVSTGIRFTTLPDATPPSFQVPSSSSSSSNPVSPSTSQPPTTITALFNPMLGHMSGAYTARVSRDLALSSRFDFNVYSYESEWTMGAEWWLRRSLTPRPSEDGEIHPPTPPPFPPPVEDVQGVVKARASTNNDVSLMWEGRLRNMLVSLGVVSDFSSRSKPIKAIGLEVSYFSSE

Gene
MDM10
Protein
Mitochondrial distribution and morphology protein 10
Organism
Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)
Length
430 amino acids
Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
Similarity
Belongs to the MDM10 family.
Mass
46.853 kDa
Sequence
MREFMHYVTNAFYGATGWNDDNTYKELNVTARELIDFPLPRGLRLTLSSLATPHFATSYQLGSVGIVDGSISYLHSSVPLTGIAARSDRIPLPALLRSYRRLHDLGSKDQQQYVGAEHAPTESTPPAVAKVDGSSLLYGRLYLPQSLLEGMVVRRFTPALQVQLSAVSERSLRNGGTLLGLVQYDKRKYGVEGLASTDGGLLGVRGLYNFGGDASSSAMNPPSGTSASETNGSGPSVEKERIYGRFSAGAELYYGTLNKSGGMSLGARFATLPAHRGTPLTATLTINPLMGNINATYAVLAREYCSLATKMEFNVYSYESEWAVGVELWSNRRPAGFLLGANPNDQAEPAPEPPRKSNERSFQAKMEWRLDDPEPEPQSPVAGEKSADDGPKEEYKGVLKARFDQNFRFGLLWEGRVKSLIFSLGTGRSD

Gene
MDM10
Protein
Mitochondrial distribution and morphology protein 10
Organism
Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294)
Length
421 amino acids
Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
Similarity
Belongs to the MDM10 family.
Mass
48.486 kDa
Sequence
MIEYMNYVIKSLQSNNDYEHLTLSSRSLLNFKIPNAFKFQLSNKSTPYTYNTIDISTNKVINGSITYLYTDAKGLDKLIKDSHNINIQSIVETYNHHCKTLNINKQNVDFKSLYYGRMYYPNSHLEGMIIKKFTTNTQVVLKWVSSFNSCNIITGYFQKYGKRNFQELIVSSNDFLCGYRFLHNFIEQPSKLNNSLYNNSYISLGGEFWLAISTLSPTCATTLRYCTHSATTGRPLTLTLSFNPLFGHLSSTYSAKTSSNSAFCVQYDFNLYSIDSNLSLGCELWKQNELIQNVSQEKSKKQEIQVPPNFYNNNSNDAKQKRILNDLNTTFESSLKKIDKERAVIENFETDLYNKDFTSVWKFSTSLRDKNLCILWDGKFKGFLLSAGTELIRINTNNENNSQSLVKFYPAKLGLQLQFST

Gene
MDM10
Protein
Mitochondrial distribution and morphology protein 10
Organism
Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)
Length
418 amino acids
Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
Similarity
Belongs to the MDM10 family.
Mass
46.383 kDa
Sequence
MYTYMEYLQKCFFHATRWNEDNIYSNITASSHALLEFLVPSGLKMDVSSRSSPNSASSFTLSNHHSLNGSLAYMYSSTQLKGTPGTRRIPLQDAIAGFKIVEPNEMRPSASGTIAPSSLLYGRMYFPGAALEAMVIRRFSPHTQLLIKCIHNPQLDKNGTLIAYFQKNTQRYSREVIYSTNDALVGFRGLYNIGSTPSWSPSPPNFDRSVVSVGAELWYAARTMSPGLSTGLRYSTRSTSTGKPLTMTLACNPILGHISSTYTVKTSVASTFCSRYDFNLFSYASNLSLGFELFNFDKNAAVERNPQLPTPTTNPSASKQNLINPIRDHSYYQTTPSTNATTYQSSQTISDSFQKLVNRSEFSSVVKVSTSLNDRLVRLLWEGRFKDFLVSSGVKVSLNPATNAVELNRFGISFSYAS

Gene
mdm10
Protein
Mitochondrial distribution and morphology protein 10
Organism
Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)
Length
400 amino acids
Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. mdm10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the tom40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of tom40 with the receptor tom22 and small TOM proteins. Can associate with the SAM(core) complex as well as the mdm12-mmm1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the tom40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
Similarity
Belongs to the MDM10 family.
Mass
45.271 kDa
Sequence
MLEFMDYVQFAFYNATKWNYENSYSQLTATAKGLLDFETPGGLRFNLSSLSSPNFATSYALGSVGLVDGSLSYLYSSLPLRTTAQSAKIDLHEIIRGYRQIQELRRVDEPWMLEQWHGGRRIDKRDTLLYGRLYLPQSTLEALYLRRITPTQQVRITAVSDSRLRNGGTILALHQYDTGKYSTETLYSTDGGLLGLRGLYNFGPDPRKEVTEPPKQMPRIDDKFYGRFSAGAELYYGTLNKSGGVSVGGRFATLPAHRGIPLTATLTLNPLMGNISSTYAVRAGKNLSLCSRLDFNVYSYESDLVLGCELWKMRAPVEERRERSMEAKLAWRLDEVDLEKEKKPEEVAGVLKARVDQNLKVGLVWEGRVKELLFTLGTSIDMKRRDQPFRALGLELQYSS

Gene
MDM10
Protein
Mitochondrial distribution and morphology protein 10
Organism
Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)
Length
392 amino acids
Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
Similarity
Belongs to the MDM10 family.
Mass
44.179 kDa
Sequence
MLDFMDNVQHAFYEASHWNVDNSYGALNATARALLDFDSPRGLRLQISSLAAPNFATSYTLGSVGVVDGSVSYLYSSLPLRKDFKSSRIDLHHVIRGFKHLQELRKPDEKWSWEQWHAGRRVDRKDTLLYGRIFLPQSRLEALYLRRLAPTRQLRIAAVSDSNLNNGGTILTLLQTDSGKYSTEYMYSTDSALMGLRGLYNFGPDPRVAPTEPTRPEQVEPVHGRFSAGAELYYGILNKSGGMSTGLRFTTLPNHPGFPYTMTLTLNPLMGNLSSTYAVKAGPSLALCSRFDFNFYSYESELQLGCELWRRRGNTDTEWAVKKLRPDWKRPAASPDDDVAGVLKAKVDQDGRVGLLWEGRIKELLFTLGASLDLKKREQIFRSVGIELQYSS

Gene
mdm10
Protein
Mitochondrial distribution and morphology protein 10
Organism
Schizosaccharomyces japonicus (strain yFS275 / FY16936)
Length
372 amino acids
Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. mdm10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the tom40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of tom40 with the receptor tom22 and small TOM proteins. Can associate with the SAM(core) complex as well as the mdm12-mmm1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the tom40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
Similarity
Belongs to the MDM10 family.
Mass
42.407 kDa
Sequence
MNSFTRALFDEYLRKTGWNRGNLYTNLTQSADEVLNLEIPSGINCDLSSIPSPNFASNWEIQMLPILNGSVSYLYSNVDLRLPQNVFGHFAQHQQKFQHLLPPYRHLKTELTDMGFERKPYLMFGKLHLPTAKLEAIFAKRISPPNNLIIRMCHTKRGILTSTSTLLHWQRDTGRSCTEILYSTDEAMIGFRKLWNSGRLQPSLFESANLTKFDPFWSVGAEVYYGALTKCVGASIGARLYSCANGVHNPYSVTCTLNPIVGHLVSTFATSHNDTRVLCSQFEFNLYSYESRLRLGMELFQRKRLLTNEDNHSDDIRQQGNDGVLRLSVSTDGDLVVAWNGQLRDFLYTVGTKVHMLSINPVFFGIHFQYSH

Gene
mdm10
Protein
Mitochondrial distribution and morphology protein 10
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Length
370 amino acids
Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. mdm10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the tom40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of tom40 with the receptor tom22 and small TOM proteins. Can associate with the SAM(core) complex as well as the mdm12-mmm1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the tom40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
Similarity
Belongs to the MDM10 family.
Mass
42.199 kDa
Sequence
MMSFNDYIFYEYLKKTNWNIHNLYCNLTQTADNILNFEIPSGVSCQLSSLTSSNFASGCKISAMPILNGSMSYVYTNVNLENLNRNITYNLQHFYEGYKHVDVPFVHYVNEFQDKKLPLRPTLLYGRMHLPSQHLDAIFATRLSPWLLFFIQGVNEIEDGVGDNLCFNWQYDTGKRCLEFVYESSGAMLGVRGLWNLNYRELNTKINMENKAPSNMRWSLGFETYYGVLTKCAGASLGMRLHSGPSHPYAPFILTCTLNPIVGHITSTFSTAEPRTKAFSAQYDFNIYSYESQLKLGIELWRSKQEMSQSTNDPTANSMSSLLKGTCSTSGDVSISWQARIRNFLLTIGTEAQLTKIDPLFFGVHFEYSK

Gene
MDM10
Protein
Mitochondrial distribution and morphology protein 10
Organism
Yarrowia lipolytica (strain CLIB 122 / E 150)
Length
353 amino acids
Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
Similarity
Belongs to the MDM10 family.
Mass
39.15 kDa
Sequence
MLTFMEHILYSFYDASGWHRDNLYALLTHSSQNLIDFRVPEGVAMNVSALSTPNSASSYTLTNLGHIQGSVAYLSTSLSLPRPHSGTLDLHTVVPGYHKLDPINSQDRIYDTIWQGGKPIHRQDSLLFGRLALPTNTLEAMYVRRFNPTTQLLVTCVSGAHLKSGGALTLYWQKDCRQYAHELLYSTNEALLGARGLYNFGVDMSKPHIASRLSVGGEFYYGVLNKSPGMSTALRYVTQSAYTGSPLTMTLTCNPIMGEFSSTYSLRTGPSSSFSTRYDFNMYSYLSNLSMGAEVWKSRDSVFKLSSSLQDKTARVLWGGRYKDILVNTGVAFDYGGRVPDVTAIGVEFQYAC